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Our Science – Bies Website

Juraj Bies, Ph.D.

Selected Publications

1)  Markus J, Garin MT, Bies J, Galili N, Raza A, Thirman MJ, Le Beau MM, Rowley JD, Liu PP, Wolff L.
Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).
Cancer Res. 67: 992-1000, 2007.
[Journal]
2)  Slape C, Hartung H, Lin YW, Bies J, Wolff L, Aplan PD.
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
Cancer Res. 67: 5148-55, 2007.
[Journal]
3)  Sramko M, Markus J, Kabát J, Wolff L, Bies J.
Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins.
J. Biol. Chem. 281: 40065-75, 2006.
[Journal]
4)  Hu X, Bies J, Wolff L.
Interferon beta increases c-Myc proteolysis in mouse monocyte/macrophage leukemia cells.
Leuk. Res. 29: 1307-14, 2005.
[Journal]
5)  Wolff L, Garin MT, Koller R, Bies J, Tessarollo L, Anver MR, Powell D, Perella C.
A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15Ink4b in myeloid cells in vivo.
Blood Cells Mol. Dis. 32: 226-31, 2004.
[Journal]
6)  Ramirez JM, Houzet L, Koller R, Bies J, Wolff L, Mougel M.
Activation of c-myb by 5' retrovirus promoter insertion in myeloid neoplasms is dependent upon an intact alternative splice donor site (SD') in gag.
Virology. 330: 398-407, 2004.
[Journal]
7)  Schmidt M, Bies J, Tamura T, Ozato K, Wolff L.
The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells.
Blood. 103: 4142-9, 2004.
[Journal]
8)  Wolff L, Garin MT, Koller R, Bies J, Liao W, Malumbres M, Tessarollo L, Powell D, Perella C.
Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice.
Oncogene. 22: 9265-74, 2003.
[Journal]
9)  Markus J, Feiková S, Sramko M, Wolff L, Bies J.
Proliferation-linked expression of the novel murine gene m4mbt encoding a nuclear zinc finger protein with four mbt domains.
Gene. 319: 117-26, 2003.
[Journal]
10)  Bies J, Markus J, Wolff L.
Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity.
J. Biol. Chem. 277: 8999-9009, 2002.
[Journal]
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This page was last updated on 11/9/2007.