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Our Science – Waugh Website

David S. Waugh, Ph.D.

Selected Publications

1)  Hogan M, Bahta M, Cherry S, Lountos GT, Tropea JE, Zhao BM, Burke TR, Waugh DS, Ulrich RG.
Biomolecular Interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase.
Chem Biol Drug Des. 81: 323-33, 2013.
2)  Raran-Kurussi S, Tözsér J, Cherry S, Tropea JE, Waugh DS.
Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases.
Anal. Biochem. 436: 142-4, 2013.
3)  Court DL, Gan J, Liang YH, Shaw GX, Tropea JE, Costantino N, Waugh DS, Ji X.
RNase III: Genetics and function; structure and mechanism.
Annu. Rev. Genet. 47: 405-31, 2013.
4)  Lountos GT, Tropea JE, Waugh DS.
Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas" disease.
Mol. Biochem. Parasitol. 187: 1-8, 2013.
5)  Austin BP, Waugh DS.
Isolation of Metarhizium anisopliae carboxypeptidase A with native disulfide bonds from the cytosol of Escherichia coli BL21(DE3).
Protein Expr. Purif. 82: 116-24, 2012.
6)  Lountos GT, Tropea JE, Waugh DS.
Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system.
Acta Crystallogr. D Biol. Crystallogr. 68: 201-9, 2012.
7)  Raran-Kurussi S, Waugh DS.
The ability to enhance the solubility of its fusion partners is an intrinsic property of maltose-binding protein but their folding is either spontaneous or chaperone-mediated.
PLoS ONE. 7: e49589, 2012.
8)  Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J, Saikh KU.
Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88.
PLoS ONE. 7: e40773, 2012.
9)  Waugh DS.
An overview of enzymatic reagents for the removal of affinity tags.
Protein Expr. Purif. 80: 283-93, 2011.
10)  Sun P, Tropea JE, Waugh DS.
Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner.
Methods Mol. Biol. 705: 259-74, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 4/10/2014.