Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health www.cancer.gov
CCR - For Our Staff| Home |

Our Science – Lubkowski Website

Jacek Tadeusz Lubkowski, Ph.D.

Selected Publications

1)  Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL, Lubkowski J, Spiegel DA.
A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules.
J Am Chem Soc. [Epub ahead of print], 2010.
In Press. [Journal]
2)  Wlodawer A, Lubkowski J, Minor W, Jaskolski M.
Is 'too creative language' acceptable in crystallography?.
Acta Crystallogr. D66: 1041-2, 2010.
[Journal]
3)  Sacha P, Barinka C, Lubkowski J, Hlouchova K, Tykvart J, Starkova J, Mlcochova P, Klusak V, Rulisek V, Konvalinka J.
Beyond proteolysis: glutamate carboxypeptidase II as a neuroprotective and prostate specific membrane antigen.
FEBS J. 276 (Suppl. 1): 17-18, 2009.
[Journal]
4)  Wang H, Byun Y, Barinka C, Pullambhatla M, Bhang HE, Fox JJ, Lubkowski J, Mease RC, Pomper MG.
Bioisosterism of urea-based GCPII inhibitors: Synthesis and structure-activity relationship studies.
Bioorg. Med. Chem. Lett. 20: 392-7, 2010.
[Journal]
5)  Zhang Y, Doherty T, Li J, Lu W, Barinka C, Lubkowski J, Hong M.
Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR.
J. Mol. Biol. 397: 408-22, 2010.
[Journal]
6)  Morales J, Villa K, Gattis J, Castro W, Colon K, Lubkowski J, Sanabria P, Hunter R, Washington AV.
Soluble TLT-1 modulates platelet-endothelial cell interactions and actin polymerization.
Blood Coagul. Fibrinolysis. 21: 229-36, 2010.
[Journal]
7)  Klusák V, Barinka C, Plechanovová A, Mlcochová P, Konvalinka J, Rulísek L, Lubkowski J.
Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods.
Biochemistry. 48: 4126-38, 2009.
[Journal]
8)  Hlouchova K, Barinka C, Konvalinka J, Lubkowski J.
Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.
FEBS J. 276: 4448-62, 2009.
[Journal]
9)  Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW.
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.
J. Clin. Invest. 119: 1489-501, 2009.
[Journal]
10)  Barinka C, Byun Y, Dusich CL, Banerjee SR, Chen Y, Castanares M, Kozikowski AP, Mease RC, Pomper MG, Lubkowski J.
Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: structural characterization.
J. Med. Chem. 51: 7737-43, 2008.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 9/2/2010.