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Our Science – Ji Website

Xinhua Ji, Ph.D.

Selected Publications

1)  Liang YH, Lavoie M, Comeau MA, Abou Elela S, Ji X.
Structure of a Eukaryotic RNase III Post-Cleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection.
Molecular Cell. 2014.
In Press. [Journal]
2)  Maciag AE, Holland RJ, Kim Y, Kumari V, Luthers CE, Sehareen WS, Biswas D, Morris NL, Ji X, Anderson LM, Saavedra JE, Keefer LK.
Nitric Oxide (NO) Releasing Poly ADP-ribose Polymerase 1 (PARP-1) Inhibitors Targeted to Glutathione S-Transferase P1-Overexpressing Cancer Cells.
J. Med. Chem. 2014.
3)  Nair S, Sanchez-Martinez S, Ji X, Rein A.
Biochemical and Biological Studies on Mouse APOBEC3.
J. Virol. 88: 3850-3860, 2014.
4)  Antony ML, Lee J, Hahm E, Kim S, Marcus AI, Kumari V, Ji X, Yang Z, Vowell CL, Wipf P, Uechi GT, Yates NA, Romero G, Sarkar SN, Singh SV.
Growth Arrest by the Antitumor Steroidal Lactone Withaferin A in Human Breast Cancer Cells Is Associated with Down-regulation and Covalent Binding at Cysteine 303 of beta-Tubulin.
J. Biol. Chem. 289: 1852-65, 2014.
5)  Court DL, Gan J, Liang Y, Shaw GX, Tropea JE, Costantino N, Waugh DS, Ji X.
RNase III: Genetics and Function; Structure and Mechanism.
Annual Review of Genetics. 47: 405-431, 2013.
6)  Das R, Liang YH, Mariano J, Li J, Huang T, King A, Tarasov SG, Weissman AM, Ji X, Byrd RA.
Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
EMBO J. 32: 2504-16, 2013.
7)  Metzger MB, Liang YH, Das R, Mariano J, Li S, Li J, Kostova Z, Byrd RA, Ji X, Weissman AM.
A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms.
Mol. Cell. 50: 516-27, 2013.
8)  Zhao J, Stagno JR, Varticovski L, Nimako E, Rishi V, McKinnon K, Akee R, Shoemaker RH, Ji X, Vinson C.
P6981, an Arylstibonic Acid, is a Novel Low Nanomolar Inhibitor of CREB binding to DNA.
Mol. Pharmacol. 82: 814-23, 2012.
9)  Stagno JR, Ma B, Li J, Altieri AS, Byrd RA, Ji X.
Crystal structure of a plectonemic RNA supercoil.
Nat Commun. 3: 901, 2012.
10)  Shi G, Shaw G, Li Y, Wu Y, Yan H, Ji X.
Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding mode.
Bioorg. Med. Chem. 20: 4303-4309, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 3/5/2014.