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Our Science – Wlodawer Website

Alexander Wlodawer, Ph.D.

Selected Publications

1)  Miller M, Jaskólski M, Rao JK, Leis J, Wlodawer A.
Crystal structure of a retroviral protease proves relationship to aspartic protease family.
Nature. 337: 576-9, 1989.
2)  Wlodawer A, Miller M, Jaskólski M, Sathyanarayana BK, Baldwin E, Weber IT, Selk LM, Clawson L, Schneider J, Kent SB.
Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease.
Science. 245: 616-21, 1989.
3)  Baldwin ET, Weber IT, St Charles R, Xuan JC, Appella E, Yamada M, Matsushima K, Edwards BF, Clore GM, Gronenborn AM.
Crystal structure of interleukin 8: symbiosis of NMR and crystallography.
Proc. Natl. Acad. Sci. U.S.A. 88: 502-6, 1991.
4)  Bujacz G, Jaskólski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA, Skalka AM.
High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J. Mol. Biol. 253: 333-46, 1995.
5)  Li M, Dimaio F, Zhou D, Gustchina A, Lubkowski J, Dauter Z, Baker D, Wlodawer A.
Crystal structure of XMRV protease differs from the structures of other retropepsins.
Nat. Struct. Mol. Biol. 18: 227-9, 2011.
6)  Jaskolski M, Dauter Z, Wlodawer A.
A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits.
FEBS J. [Epub ahead of print], 2014.
7)  Aranko AS, Oeemig JS, Zhou D, Kajander T, Wlodawer A, Iwaï H.
Structure-based engineering and comparison of novel split inteins for protein ligation.
Mol Biosyst. 10: 1023-1034, 2014.
8)  Zheng H, Hou J, Zimmerman MD, Wlodawer A, Minor W.
The future of crystallography in drug discovery.
Expert Opin Drug Discov. 9: 125-37, 2014.
9)  Domagalski MJ, Zheng H, Zimmerman MD, Dauter Z, Wlodawer A, Minor W.
The quality and validation of structures from structural genomics.
Methods Mol. Biol. 1091: 297-314, 2014.
10)  Wlodawer A, Gustchina A, James MN.
Rawlings N, Salvesen G, eds.
Chapter 2 - Catalytic Pathways of Aspartic Peptidases. In: Handbook of Proteolytic Enzymes (Third Edition). Volume 1.
London: Academic Press/Elsevier; 2013. p. 19-26 [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 6/17/2014.