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Our Science – Kleiner Website

David E. Kleiner, M.D., Ph.D.

Selected Publications

1)  Noureddin M, Wright EC, Alter H, Clark S, Thomas E, Chen R, Zhao X, Conry-Cantilena C, Kleiner D, Liang TJ, Ghany MG.
Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: A longitudinal analysis.
Hepatology. 2013.
[Journal]
2)  Fricker Z, Levy E, Kleiner D, Taylor JG, Koh C, Holland SM, Heller T.
Case series: biliary leak after transjugular liver biopsy.
Am. J. Gastroenterol. 108: 145-7, 2013.
[Journal]
3)  Noureddin M, Yates KP, Vaughn IA, Neuschwander-Tetri BA, Sanyal AJ, McCullough A, Merriman R, Hameed B, Doo E, Kleiner DE, Behling C, Loomba R.
Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients.
Hepatology. 2013.
[Journal]
4)  Koh C, Turner T, Zhao X, Minniti CP, Feld JJ, Simpson J, Demino M, Conrey AK, Jackson MJ, Seamon C, Kleiner DE, Kato GJ, Heller T.
Liver stiffness increases acutely during sickle cell vaso-occlusive crisis.
Am. J. Hematol. 2013.
[Journal]
5)  Holczbauer A, Factor VM, Andersen JB, Marquardt JU, Kleiner DE, Raggi C, Kitade M, Seo D, Akita H, Durkin ME, Thorgeirsson SS.
Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types.
Gastroenterology. 145: 221-31, 2013.
[Journal]
6)  Osinusi A, Meissner EG, Lee YJ, Bon D, Heytens L, Nelson A, Sneller M, Kohli A, Barrett L, Proschan M, Herrmann E, Shivakumar B, Gu W, Kwan R, Teferi G, Talwani R, Silk R, Kotb C, Wroblewski S, Fishbein D, Dewar R, Highbarger H, Zhang X, Kleiner D, Wood BJ, Chavez J, Symonds WT, Subramanian M, McHutchison J, Polis MA, Fauci AS, Masur H, Kottilil S.
Sofosbuvir and ribavirin for hepatitis C genotype 1 in patients with unfavorable treatment characteristics: a randomized clinical trial.
JAMA. 310: 804-11, 2013.
[Journal]
7)  Hoofnagle JH, Van Natta ML, Kleiner DE, Clark JM, Kowdley KV, Loomba R, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J.
Vitamin E and changes in serum alanine aminotransferase levels in patients with non-alcoholic steatohepatitis.
Aliment. Pharmacol. Ther. 38: 134-43, 2013.
[Journal]
8)  Georgoff P, Thomasson D, Louie A, Fleischman E, Dutcher L, Mani H, Kottilil S, Morse C, Dodd L, Kleiner D, Hadigan C.
Hydrogen-1 MR spectroscopy for measurement and diagnosis of hepatic steatosis.
AJR Am J Roentgenol. 199: 2-7, 2012.
[Journal]
9)  Vanderbeck S, Bockhorst J, Komorowski R, Kleiner DE, Gawrieh S.
Automatic classification of white regions in liver biopsies by supervised machine learning.
Hum. Pathol. 45: 785-92, 2014.
[Journal]
10)  Zhou Q, Yang D, Ombrello AK, Zavialov AV, Toro C, Zavialov AV, Stone DL, Chae JJ, Rosenzweig SD, Bishop K, Barron KS, Kuehn HS, Hoffmann P, Negro A, Tsai WL, Cowen EW, Pei W, Milner JD, Silvin C, Heller T, Chin DT, Patronas NJ, Barber JS, Lee CC, Wood GM, Ling A, Kelly SJ, Kleiner DE, Mullikin JC, Ganson NJ, Kong HH, Hambleton S, Candotti F, Quezado MM, Calvo KR, Alao H, Barham BK, Jones A, Meschia JF, Worrall BB, Kasner SE, Rich SS, Goldbach-Mansky R, Abinun M, Chalom E, Gotte AC, Punaro M, Pascual V, Verbsky JW, Torgerson TR, Singer NG, Gershon TR, Ozen S, Karadag O, Fleisher TA, Remmers EF, Burgess SM, Moir SL, Gadina M, Sood R, Hershfield MS, Boehm M, Kastner DL, Aksentijevich I.
Early-onset stroke and vasculopathy associated with mutations in ADA2.
N. Engl. J. Med. 370: 911-20, 2014.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 8/6/2014.