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Our Science – Huppi Website

Konrad Huppi, Ph.D.

Selected Publications

1)  Barsotti AM, Beckerman R, Laptenko O, Huppi K, Caplen NJ, Prives C.
p53-Dependent induction of PVT1 and miR-1204.
J. Biol. Chem. 287: 2509-19, 2012.
2)  Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ.
Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Mol. Cancer. 11: 1, 2012.
3)  Huppi K, Pitt JJ, Wahlberg BM, Caplen NJ.
The 8q24 gene desert: an oasis of non-coding transcriptional activity.
Front Genet. 3: 69, 2012.
4)  Huppi K, Pitt J, Wahlberg B, Caplen NJ.
Genomic instability and mouse microRNAs.
Toxicol. Mech. Methods. 21: 325-33, 2011.
5)  Mackiewicz M, Huppi K, Pitt JJ, Dorsey TH, Ambs S, Caplen NJ.
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA.
Breast Cancer Res. Treat. 130: 663-79, 2011.
6)  McKean D, Huppi K, Bell M, Staudt L, Gerhard W, Weigert M.
Pillars article: generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA, 81: 3180-3184, May 1984.
J. Immunol. 180: 5765-9, 2008.
7)  Beck-Engeser GB, Lum AM, Huppi K, Caplen NJ, Wang BB, Wabl M.
Pvt1-encoded microRNAs in oncogenesis.
Retrovirology. 5: 4, 2008.
8)  Huppi K, Volfovsky N, Runfola T, Jones TL, Mackiewicz M, Martin SE, Mushinski JF, Stephens R, Caplen NJ.
The identification of microRNAs in a genomically unstable region of human chromosome 8q24.
Mol. Cancer Res. 6: 212-21, 2008.
9)  Raveche ES, Salerno E, Scaglione BJ, Manohar V, Abbasi F, Lin Y, Fredrickson T, Landgraf P, Ramachandra S, Huppi K, Toro JR, Zenger VE, Metcalf RA, Marti GE.
Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice.
Blood. 109: 5079-86, 2007.
10)  Huppi K, Volfovsky N, Mackiewicz M, Runfola T, Jones TL, Martin SE, Stephens R, Caplen NJ.
MicroRNAs and genomic instability.
Semin. Cancer Biol. 17: 65-73, 2007.
Click Here to View Expanded Bibliography.

This page was last updated on 4/9/2014.