Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health www.cancer.gov
CCR - For Our Staff| Home |

Our Science – Bonner Website

William M. Bonner, Ph.D.

Selected Publications

1)  Moroni M, Maeda D, Whitnall MH, Bonner WM, Redon CE.
Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model.
Int J Mol Sci. 14: 14119-35, 2013.
[Journal]
2)  Dickey JS, Gonzalez Y, Aryal B, Mog S, Nakamura AJ, Redon CE, Baxa U, Rosen E, Cheng G, Zielonka J, Parekh P, Mason KP, Joseph J, Kalyanaraman B, Bonner W, Herman E, Shacter E, Rao VA.
Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model.
PLoS ONE. 8: e70575, 2013.
[Journal]
3)  Weyemi U, Redon CE, Parekh PR, Dupuy C, Bonner WM.
NADPH Oxidases NOXs and DUOXs as Putative Targets for Cancer Therapy.
Anticancer Agents Med Chem. 13: 502-14, 2013.
[Journal]
4)  Talbert PB, Ahmad K, Almouzni G, Ausió J, Berger F, Bhalla PL, Bonner WM, Cande WZ, Chadwick BP, Chan SW, Cross GA, Cui L, Dimitrov SI, Doenecke D, Eirin-López JM, Gorovsky MA, Hake SB, Hamkalo BA, Holec S, Jacobsen SE, Kamieniarz K, Khochbin S, Ladurner AG, Landsman D, Latham JA, Loppin B, Malik HS, Marzluff WF, Pehrson JR, Postberg J, Schneider R, Singh MB, Smith MM, Thompson E, Torres-Padilla ME, Tremethick DJ, Turner BM, Waterborg JH, Wollmann H, Yelagandula R, Zhu B, Henikoff S.
A unified phylogeny-based nomenclature for histone variants.
Epigenetics Chromatin. 5: 7, 2012.
[Journal]
5)  Dickey JS, Baird BJ, Redon CE, Avdoshina V, Palchik G, Wu J, Kondratyev A, Bonner WM, Martin OA.
Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity.
Nucleic Acids Res. 40: 10274-86, 2012.
[Journal]
6)  Ivashkevich A, Redon CE, Nakamura AJ, Martin RF, Martin OA.
Use of the ?-H2AX assay to monitor DNA damage and repair in translational cancer research.
Cancer Lett. 327: 123-33, 2012.
[Journal]
7)  Redon CE, Weyemi U, Parekh PR, Huang D, Burrell AS, Bonner WM.
gamma-H2AX and other histone post-translational modifications in the clinic.
Biochim Biophys Acta. [Epub ahead of print], 2012.
[Journal]
8)  Kinders RJ, Hollingshead M, Lawrence S, Ji J, Tabb B, Bonner WM, Pommier Y, Rubinstein L, Evrard YA, Parchment RE, Tomaszewski J, Doroshow JH.
Development of a validated immunofluorescence assay for gammaH2AX as a pharmacodynamic marker of topoisomerase I inhibitor activity.
Clin. Cancer Res. 16: 5447-57, 2010.
[Journal]
9)  Redon CE, Nakamura AJ, Zhang YW, Ji JJ, Bonner WM, Kinders RJ, Parchment RE, Doroshow JH, Pommier Y.
Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.
Clin. Cancer Res. 16: 4532-42, 2010.
[Journal]
10)  Nakamura AJ, Rao VA, Pommier Y, Bonner WM.
The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks.
Cell Cycle. 9: 389-97, 2010.
[Journal]
11)  Redon CE, Nakamura AJ, Gouliaeva K, Rahman A, Blakely WF, Bonner WM.
The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates.
PLoS ONE. 5: e15544, 2010.
[Journal]
12)  Redon CE, Dickey JS, Nakamura AJ, Kareva IG, Naf D, Nowsheen S, Kryston TB, Bonner WM, Georgakilas AG, Sedelnikova OA.
Tumors induce complex DNA damage in distant proliferative tissues in vivo.
Proc. Natl. Acad. Sci. U.S.A. 107: 17992-7, 2010.
[Journal]
13)  Rogakou EP, Boon C, Redon C, Bonner WM.
Megabase chromatin domains involved in DNA double-strand breaks in vivo.
J. Cell Biol. 146: 905-16, 1999.
[Journal]
14)  Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM.
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
J. Biol. Chem. 273: 5858-68, 1998.
[Journal]
15)  Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A.
Genomic instability in mice lacking histone H2AX.
Science. 296: 922-7, 2002.
[Journal]
16)  West MH, Bonner WM.
Histone 2A, a heteromorphous family of eight protein species.
Biochemistry. 19: 3238-45, 1980.
[Journal]
17)  Adams G, Martin OA, Roos DE, Lobachevsky PN, Potter AE, Zacest AC, Bezak E, Bonner WM, Martin RF, Leong T.
Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma.
Radiother Oncol. [Epub ahead of print], 2012.
[Journal]
18)  Weyemi U, Parekh PR, Redon CE, Bonner WM.
SOD2 deficiency promotes aging phenotypes in mouse skin.
Aging. 4: 116-8, 2012.
[Journal]
19)  Redon C, Nakamura A, Sordet O, Dickey J, Gouliaeva K, Tabb B, Lawrence S, Kinders R, Bonner W, Sedelnikova O.
gamma-H2AX Detection in Peripheral Blood Lymphocytes, Splenocytes, Bone Marrow, Xenografts, and Skin. In: DNA Damage Detection In Situ, Ex Vivo, and In Vivo.
Springer Science; 2011. In Press. [Book Chapter]
20)  Redon CE, Nakamura AJ, Sordet O, Dickey JS, Gouliaeva K, Tabb B, Lawrence S, Kinders RJ, Bonner WM, Sedelnikova OA.
gamma-H2AX detection in peripheral blood lymphocytes, splenocytes, bone marrow, xenografts, and skin.
Methods Mol. Biol. 682: 249-70, 2011.
[Journal]
21)  Ivashkevich AN, Martin OA, Smith AJ, Redon CE, Bonner WM, Martin RF, Lobachevsky PN.
gammaH2AX foci as a measure of DNA damage: a computational approach to automatic analysis.
Mutat. Res. 711: 49-60, 2011.
[Journal]
22)  Dickey JS, Zemp FJ, Altamirano A, Sedelnikova OA, Bonner WM, Kovalchuk O.
H2AX phosphorylation in response to DNA double-strand break formation during bystander signalling: effect of microRNA knockdown.
Radiat Prot Dosimetry. 143: 264-9, 2011.
[Journal]
23)  Redon CE, Bonner WM.
High salt and DNA double-strand breaks.
Proc. Natl. Acad. Sci. U.S.A. 108: 20281-2, 2011.
[Journal]
24)  Baird BJ, Dickey JS, Nakamura AJ, Redon CE, Parekh P, Griko YV, Aziz K, Georgakilas AG, Bonner WM, Martin OA.
Hypothermia postpones DNA damage repair in irradiated cells and protects against cell killing.
Mutat. Res. 711: 142-9, 2011.
[Journal]
25)  Martin OA, Redon CE, Dickey JS, Nakamura AJ, Bonner WM.
Para-inflammation mediates systemic DNA damage in response to tumor growth.
Commun Integr Biol. 4: 78-81, 2011.
[Journal]
26)  Redon CE, Nakamura AJ, Gouliaeva K, Rahman A, Blakely WF, Bonner WM.
Q(gamma-H2AX), an analysis method for partial-body radiation exposure using gamma-H2AX in nonhuman primate lymphocytes.
Radiat Meas. 46: 877-881, 2011.
[Journal]
27)  Redon CE, Nakamura AJ, Martin OA, Parekh PR, Weyemi US, Bonner WM.
Recent developments in the use of gamma-H2AX as a quantitative DNA double-strand break biomarker.
Aging. 3: 168-74, 2011.
[Journal]
28)  Martin OA, Redon CE, Nakamura AJ, Dickey JS, Georgakilas AG, Bonner WM.
Systemic DNA damage related to cancer.
Cancer Res. 71: 3437-41, 2011.
[Journal]
29)  Peddi P, Loftin CW, Dickey JS, Hair JM, Burns KJ, Aziz K, Francisco DC, Panayiotidis MI, Sedelnikova OA, Bonner WM, Winters TA, Georgakilas AG.
DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.
Free Radic. Biol. Med. 48: 1435-43, 2010.
[Journal]
30)  Nakamura AJ, Redon CE, Bonner WM.
gammaH2AX: Applications for the evaluation of telomerase-based cancer therapy.
Cell Cycle. 9: 3385-6, 2010.
[Journal]
31)  Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J.
Impact papers on aging in 2009.
Aging. 2: 111-21, 2010.
[Journal]
32)  Kovalchuk O, Zemp FJ, Filkowski J, Altamirano A, Dickey JS, Jenkins-Baker G, Marino SA, Brenner DJ, Bonner WM, Sedelnikova OA.
microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways.
Carcinogenesis. 31: 1882-8, 2010.
[Journal]
33)  Nowsheen S, Wukovich RL, Aziz K, Kalogerinis PT, Richardson CC, Panayiotidis MI, Bonner WM, Sedelnikova OA, Georgakilas AG.
Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
Mutat. Res. 674: 131-6, 2009.
[Journal]
34)  Sordet O, Redon CE, Guirouilh-Barbat J, Smith S, Solier S, Douarre C, Conti C, Nakamura AJ, Das BB, Nicolas E, Kohn KW, Bonner WM, Pommier Y.
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
EMBO Rep. 10: 887-93, 2009.
[Journal]
35)  Redon CE, Dickey JS, Bonner WM, Sedelnikova OA.
gamma-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin.
Adv Space Res. 43: 1171-1178, 2009.
[Journal]
36)  Dickey JS, Redon CE, Nakamura AJ, Baird BJ, Sedelnikova OA, Bonner WM.
H2AX: functional roles and potential applications.
Chromosoma. 118: 683-92, 2009.
[Journal]
37)  Dickey JS, Baird BJ, Redon CE, Sokolov MV, Sedelnikova OA, Bonner WM.
Intercellular Communication of Cellular Stress Monitored by {gamma}-H2AX Induction.
Carcinogenesis. 10: 1686-95, 2009.
[Journal]
38)  Sedelnikova OA, Redon CE, Dickey JS, Nakamura AJ, Georgakilas AG, Bonner WM.
Role of oxidatively induced DNA lesions in human pathogenesis.
Mutat. Res. 704: 152-9, 2009.
[Journal]
39)  Nakamura AJ, Redon CE, Bonner WM, Sedelnikova OA.
Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells.
Aging. 1: 212-8, 2009.
[Journal]
40)  Kumari D, Somma V, Nakamura AJ, Bonner WM, D'Ambrosio E, Usdin K.
The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome.
Nucleic Acids Res. 13: 4385-92, 2009.
[Journal]
41)  Nakamura AJ, Chiang YJ, Hathcock KS, Horikawa I, Sedelnikova OA, Hodes RJ, Bonner WM.
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence.
Epigenetics Chromatin. 1: 6, 2008.
[Journal]
42)  Sedelnikova OA, Horikawa I, Redon C, Nakamura A, Zimonjic DB, Popescu NC, Bonner WM.
Delayed kinetics of DNA double-strand break processing in normal and pathological aging.
Aging Cell. 7: 89-100, 2008.
[Journal]
43)  Bonner WM, Redon CE, Dickey JS, Nakamura AJ, Sedelnikova OA, Solier S, Pommier Y.
GammaH2AX and cancer.
Nat. Rev. Cancer. 8: 957-67, 2008.
[Journal]
44)  Sonoda E, Zhao GY, Kohzaki M, Dhar PK, Kikuchi K, Redon C, Pilch DR, Bonner WM, Nakano A, Watanabe M, Nakayama T, Takeda S, Takami Y.
Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.
DNA Repair (Amst.). 6: 280-92, 2007.
[Journal]
45)  Sedelnikova OA, Nakamura A, Kovalchuk O, Koturbash I, Mitchell SA, Marino SA, Brenner DJ, Bonner WM.
DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models.
Cancer Res. 67: 4295-302, 2007.
[Journal]
46)  Sokolov MV, Dickey JS, Bonner WM, Sedelnikova OA.
gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication.
Cell Cycle. 6: 2210-2, 2007.
[Journal]
47)  Smilenov LB, Hall EJ, Bonner WM, Sedelnikova OA.
A microbeam study of DNA double-strand breaks in bystander primary human fibroblasts.
Radiat Prot Dosimetry. 122: 256-9, 2006.
[Journal]
48)  Sedelnikova OA, Bonner WM.
GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence.
Cell Cycle. 5: 2909-13, 2006.
[Journal]
49)  Redon C, Pilch DR, Bonner WM.
Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.
Genetics. 172: 67-76, 2006.
[Journal]
50)  Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bonner WM, Aladjem MI, Kohn KW, Pommier Y.
p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.
Oncogene. 25: 2839-49, 2006.
[Journal]
51)  Nakamura A, Sedelnikova OA, Redon C, Pilch DR, Sinogeeva NI, Shroff R, Lichten M, Bonner WM.
Techniques for gamma-H2AX detection.
Meth. Enzymol. 409: 236-50, 2006.
[Journal]
52)  To KK, Sedelnikova OA, Samons M, Bonner WM, Huang LE.
The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression.
EMBO J. 2006.
[Journal]
53)  Sedelnikova OA, Panyutin IV, Neumann RD, Bonner WM, Panyutin IG.
Assessment of DNA damage produced by 125I-triplex-forming oligonucleotides in cells.
Int. J. Radiat. Biol. 80: 927-31, 2005.
[Journal]
54)  Panyutin IV, Sedelnikova OA, Bonner WM, Panyutin IG, Neumann RD.
DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their successful delivery into cell nuclei.
Ann. N. Y. Acad. Sci. 1058: 140-50, 2005.
[Journal]
55)  Sokolov MV, Smilenov LB, Hall EJ, Panyutin IG, Bonner WM, Sedelnikova OA.
Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts.
Oncogene. 24: 7257-65, 2005.
[Journal]
56)  Shroff R, Arbel-Eden A, Pilch D, Ira G, Bonner WM, Petrini JH, Haber JE, Lichten M.
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break.
Curr. Biol. 14: 1703-11, 2004.
[Journal]
57)  Bonner WM.
Phenomena leading to cell survival values which deviate from linear-quadratic models.
Mutat. Res. 568: 33-9, 2004.
[Journal]
58)  Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC.
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.
Nat. Cell Biol. 6: 168-70, 2004.
[Journal]
59)  Pilch DR, Redon C, Sedelnikova OA, Bonner WM.
Two-dimensional gel analysis of histones and other H2AX-related methods.
Meth. Enzymol. 375: 76-88, 2004.
[Journal]
60)  Pilch DR, Sedelnikova OA, Redon C, Celeste A, Nussenzweig A, Bonner WM.
Characteristics of gamma-H2AX foci at DNA double-strand breaks sites.
Biochem. Cell Biol. 81: 123-9, 2003.
[Journal]
61)  Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A.
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility.
Cell. 114: 371-83, 2003.
[Journal]
62)  Fernandez-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM, Manova K, Burgoyne P, Nussenzweig A.
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis.
Dev. Cell. 4: 497-508, 2003.
[Journal]
63)  Sedelnikova OA, Pilch DR, Redon C, Bonner WM.
Histone H2AX in DNA damage and repair.
Cancer Biol. Ther. 2: 233-5, 2003.
[Journal]
64)  Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A.
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.
Nat. Cell Biol. 5: 675-9, 2003.
[Journal]
65)  Bonner WM.
Low-dose radiation: thresholds, bystander effects, and adaptive responses.
Proc. Natl. Acad. Sci. U.S.A. 100: 4973-5, 2003.
[Journal]
66)  Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, Sedelnikova OA, Pilch DR, Rogakou EP, Celeste A, Chen HT, Nussenzweig A, Aladjem MI, Bonner WM, Pommier Y.
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.
J. Biol. Chem. 278: 20303-12, 2003.
[Journal]
67)  Redon C, Pilch DR, Rogakou EP, Orr AH, Lowndes NF, Bonner WM.
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage.
EMBO Rep. 4: 678-84, 2003.
[Journal]
68)  Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A.
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Nat. Cell Biol. 4: 993-7, 2002.
[Journal]
69)  Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM.
Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody.
Radiat. Res. 158: 486-92, 2002.
[Journal]
70)  Limoli CL, Giedzinski E, Bonner WM, Cleaver JE.
UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization.
Proc. Natl. Acad. Sci. U.S.A. 99: 233-8, 2002.
[Journal]
71)  Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A.
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.
Nature. 414: 660-5, 2001.
[Journal]
72)  Abbott DW, Ivanova VS, Wang X, Bonner WM, Ausió J.
Characterization of the stability and folding of H2A.Z chromatin particles: implications for transcriptional activation.
J. Biol. Chem. 276: 41945-9, 2001.
[Journal]
73)  Mahadevaiah SK, Turner JM, Baudat F, Rogakou EP, de Boer P, Blanco-Rodríguez J, Jasin M, Keeney S, Bonner WM, Burgoyne PS.
Recombinational DNA double-strand breaks in mice precede synapsis.
Nat. Genet. 27: 271-6, 2001.
[Journal]
74)  Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM.
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.
Curr. Biol. 10: 886-95, 2000.
[Journal]
75)  Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM.
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139.
J. Biol. Chem. 275: 9390-5, 2000.
[Journal]
76)  Rogakou EP, Redon C, Boon C, Johnson K, Bonner WM.
Rapid histone extraction for electrophoretic analysis.
BioTechniques. 28: 38-40, 42, 46, 2000.
[Journal]
77)  Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A.
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX.
Science. 290: 1962-5, 2000.
[Journal]
78)  Hatch CL, Bonner WM.
An upstream region of the H2AZ gene promoter modulates promoter activity in different cell types.
Biochim. Biophys. Acta. 1305: 59-62, 1996.
[Journal]
79)  Orr A, Ivanova VS, Bonner WM.
.
BioTechniques. 19: 204-6, 1995.
[Journal]
80)  Hatch CL, Bonner WM.
Characterization of the proximal promoter of the human histone H2A.Z gene.
DNA Cell Biol. 14: 257-66, 1995.
[Journal]
81)  Ivanova VS, Hatch CL, Bonner WM.
Characterization of the human histone H2A.X gene. Comparison of its promoter with other H2A gene promoters.
J. Biol. Chem. 269: 24189-94, 1994.
[Journal]
82)  Ivanova VS, Zimonjic D, Popescu N, Bonner WM.
Chromosomal localization of the human histone H2A.X gene to 11q23.2-q23.3 by fluorescence in situ hybridization.
Hum. Genet. 94: 303-6, 1994.
[Journal]
83)  Ivanova VS, Bonner WM.
Expression of a marked H2A histone protein in mammalian cells.
Exp. Cell Res. 215: 63-7, 1994.
[Journal]
84)  Bonner WM, Mannironi C, Orr A, Pilch DR, Hatch CL.
Histone H2A.X gene transcription is regulated differently than transcription of other replication-linked histone genes.
Mol. Cell. Biol. 13: 984-92, 1993.
[Journal]
85)  Hatch CL, Bonner WM.
The human histone H2A.Z gene. Sequence and regulation.
J. Biol. Chem. 265: 15211-8, 1990.
[Journal]
86)  Mannironi C, Bonner WM, Hatch CL.
H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals.
Nucleic Acids Res. 17: 9113-26, 1989.
[Journal]
87)  Bonner WM, Wu RS, Panusz HT, Muneses C.
Kinetics of accumulation and depletion of soluble newly synthesized histone in the reciprocal regulation of histone and DNA synthesis.
Biochemistry. 27: 6542-50, 1988.
[Journal]
88)  Hatch CL, Bonner WM.
Sequence of cDNAs for mammalian H2A.Z, an evolutionarily diverged but highly conserved basal histone H2A isoprotein species.
Nucleic Acids Res. 16: 1113-24, 1988.
[Journal]
89)  Bonner WM.
Autoradiograms: 35S and 32P.
Meth. Enzymol. 152: 55-61, 1987.
[Journal]
90)  Hatch CL, Bonner WM.
Direct analysis of RNA in whole cell and cytoplasmic extracts by gel electrophoresis.
Anal. Biochem. 162: 283-90, 1987.
[Journal]
91)  D'Incalci M, Allavena P, Wu RS, Bonner WM.
H1 variant synthesis in proliferating and quiescent human cells.
Eur. J. Biochem. 154: 273-9, 1986.
[Journal]
92)  Wu RS, Panusz HT, Hatch CL, Bonner WM.
Histones and their modifications.
CRC Crit. Rev. Biochem. 20: 201-63, 1986.
[Journal]
93)  Mueller RD, Yasuda H, Hatch CL, Bonner WM, Bradbury EM.
Identification of ubiquitinated histones 2A and 2B in Physarum polycephalum. Disappearance of these proteins at metaphase and reappearance at anaphase.
J. Biol. Chem. 260: 5147-53, 1985.
[Journal]
94)  Sariban E, Wu RS, Erickson LC, Bonner WM.
Interrelationships of protein and DNA syntheses during replication of mammalian cells.
Mol. Cell. Biol. 5: 1279-86, 1985.
[Journal]
95)  Wu RS, Bonner WM.
Mechanism for differential sensitivity of the chromosome and growth cycles of mammalian cells to the rate of protein synthesis.
Mol. Cell. Biol. 5: 2959-66, 1985.
[Journal]
96)  West MH, Pantazis P, Bonner WM.
Studies on nuclease digestion of chromatin phosphorylated in vivo.
J. Biol. Chem. 260: 4558-60, 1985.
[Journal]
97)  Bonner WM.
Fluorography for the detection of radioactivity in gels.
Meth. Enzymol. 104: 460-5, 1984.
[Journal]
98)  Pataryas TA, Sekeri-Pataryas KT, Bonner WM, Marinou VA.
Histone variants of the insect Plodia interpunctella during metamorphosis.
Comp. Biochem. Physiol., B. 77: 749-53, 1984.
[Journal]
99)  Pantazis P, West MH, Bonner WM.
Phosphorylation of histones in cells treated with hypertonic and acidic media.
Mol. Cell. Biol. 4: 1186-8, 1984.
[Journal]
100)  Pantazis P, Bonner WM.
Specific alterations in the pattern of histone-3 synthesis during conversion of human leukemic cells to terminally differentiated cells in culture.
Differentiation. 28: 186-90, 1984.
[Journal]
101)  Wu RS, Tsai S, Bonner WM.
Changes in histone H3 composition and synthesis pattern during lymphocyte activation.
Biochemistry. 22: 3868-73, 1983.
[Journal]
102)  Hatch CL, Bonner WM, Moudrianakis EN.
Differential accessibility of the amino and carboxy termini of histone H2A in the nucleosome and its histone subunits.
Biochemistry. 22: 3016-23, 1983.
[Journal]
103)  Filipski J, Kohn KW, Bonner WM.
Differential crosslinking of histones and non-histones in nuclei by cis-Pt(II).
FEBS Lett. 152: 105-8, 1983.
[Journal]
104)  Wu RS, Perry LJ, Bonner WM.
Fate of newly synthesized histones in G1 and G0 cells.
FEBS Lett. 162: 161-6, 1983.
[Journal]
105)  Hatch CL, Bonner WM, Moudrianakis EN.
Minor histone 2A variants and ubiquinated forms in the native H2A:H2B dimer.
Science. 221: 468-70, 1983.
[Journal]
106)  West MH, Bonner WM.
Structural comparisons of mouse histones 2A.X and 2A.Z with 2A.1 and 2A.2.
Comp. Biochem. Physiol., B. 76: 455-64, 1983.
[Journal]
107)  Bonner WM.
Use of fluorography for sensitive isotope detection in polyacrylamide gel electrophoresis and related techniques.
Meth. Enzymol. 96: 215-22, 1983.
[Journal]
108)  Pantazis P, Bonner WM.
Butyrate-induced histone hyperacetylation in human and mouse cells: estimation of putative sites of histone acetylation in vivo.
J. Cell. Biochem. 20: 225-35, 1982.
[Journal]
109)  Wu RS, Nishioka D, Bonner WM.
Differential conservation of histone 2A variants between mammals and sea urchins.
J. Cell Biol. 93: 426-31, 1982.
[Journal]
110)  Wu RS, Stedman JD, West MH, Pantazis P, Bonner WM.
Discontinuous agarose electrophoretic system for the recovery of stained proteins from polyacrylamide gels.
Anal. Biochem. 124: 264-71, 1982.
[Journal]
111)  Wu RS, Tsai S, Bonner WM.
Patterns of histone variant synthesis can distinguish G0 from G1 cells.
Cell. 31: 367-74, 1982.
[Journal]
112)  Wu RS, Kohn KW, Bonner WM.
Metabolism of ubiquitinated histones.
J. Biol. Chem. 256: 5916-20, 1981.
[Journal]
113)  Pantazis P, Bonner WM.
Quantitative determination of histone modification. H2A acetylation and phosphorylation.
J. Biol. Chem. 256: 4669-75, 1981.
[Journal]
114)  Wu RS, Bonner WM.
Separation of basal histone synthesis from S-phase histone synthesis in dividing cells.
Cell. 27: 321-30, 1981.
[Journal]
115)  West MH, Bonner WM.
Histone 2B can be modified by the attachment of ubiquitin.
Nucleic Acids Res. 8: 4671-80, 1980.
[Journal]
116)  Filipski J, Kohn KW, Bonner WM.
The nature of inactivating lesions produced by platinum(II) complexes in phage lambda DNA.
Chem. Biol. Interact. 32: 321-30, 1980.
[Journal]
117)  Bonner WM, West MH, Stedman JD.
Two-dimensional gel analysis of histones in acid extracts of nuclei, cells, and tissues.
Eur. J. Biochem. 109: 17-23, 1980.
[Journal]
118)  Bonner WM, Stedman JD.
Histone 1 is proximal to histone 2A and to A24.
Proc. Natl. Acad. Sci. U.S.A. 76: 2190-4, 1979.
[Journal]
119)  Filipski J, Kohn KW, Prather R, Bonner WM.
Thiourea reverses cross-links and restores biological activity in DNA treated with dichlorodiaminoplatinum (II).
Science. 204: 181-3, 1979.
[Journal]
120)  Thomas CB, Kohn KW, Bonner WM.
Characterization of DNA-protein cross-links formed by treatment of L1210 cells and nuclei with bis(2-chloroethyl)methylamine (nitrogen mustard).
Biochemistry. 17: 3954-8, 1978.
[Journal]
121)  Zinder O, Hoffman PG, Bonner WM, Pollard HB.
Comparison of chemical properties of purified plasma membranes and secretory vesicle membranes from bovine adrenal medulla.
Cell Tissue Res. 188: 153-70, 1978.
[Journal]
122)  Bonner WM, Stedman JD.
Efficient fluorography of 3H and 14C on thin layers.
Anal. Biochem. 89: 247-56, 1978.
[Journal]
123)  Bonner WM.
Proximity and accessibility studies of histones in nuclei and free nucleosomes.
Nucleic Acids Res. 5: 71-85, 1978.
[Journal]
124)  Barker JL, Neale JH, Bonner WM.
Slab gel analysis of rapidly transported proteins in the isolated frog nervous system.
Brain Res. 124: 191-6, 1977.
[Journal]
125)  Hoffman PG, Zinder O, Bonner WM, Pollard HB.
Role of ATP and beta-gamma-iminoadenosinetriphosphate in the stimulation of epinephrine and protein release from isolated adrenal secretory vesicles.
Arch. Biochem. Biophys. 176: 375-88, 1976.
[Journal]
126)  Bonner WM, Jonsson H, Malanos C, Bryant M.
Changes in the lipids of human articular cartilage with age.
Arthritis Rheum. 18: 461-73, 1975.
[Journal]
127)  Bonner WM.
Protein migration into nuclei. I. Frog oocyte nuclei in vivo accumulate microinjected histones, allow entry to small proteins, and exclude large proteins.
J. Cell Biol. 64: 421-30, 1975.
[Journal]
128)  Bonner WM.
Protein migration into nuclei. II. Frog oocyte nuclei accumulate a class of microinjected oocyte nuclear proteins and exclude a class of microinjected oocyte cytoplasmic proteins.
J. Cell Biol. 64: 431-7, 1975.
[Journal]
129)  Bonner WM, Pollard HB.
The presence of F3-F2a1 dimers and F1 oligomers in chromatin.
Biochem. Biophys. Res. Commun. 64: 282-8, 1975.
[Journal]
130)  Bonner WM, Laskey RA.
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.
Eur. J. Biochem. 46: 83-8, 1974.
[Journal]
131)  Bonner WM, Bloch K.
Purification and properties of fatty acyl thioesterase I from Escherichia coli.
J. Biol. Chem. 247: 3123-33, 1972.
[Journal]
Click Here to View Collapsed Bibliography.

This page was last updated on 9/16/2013.