Our Science – Aladjem Website

Mirit I Aladjem, Ph.D.

Selected Publications

1) Aladjem MI.
Replication in Context: Dynamic Regulation of DNA Replication Patterns in Metazoans.
Nature Reviews Genetics. 8: 588-600, 2007. Full Text Article. [Journal]

2) Shimura T, Torres MJ, Martin MM, Rao VA, Pommier Y, Katsura M, Miyagawa K, Aladjem MI.
Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress.
J. Mol. Biol. 375: 1152-64, 2008. [Journal]

3) Shimura T, Martin MM, Torres MJ, Gu C, Pluth JM, DiBernardi MA, McDonald JS, Aladjem MI.
DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication.
J. Mol. Biol. 367: 665-80, 2007. [Journal]

4) Kohn KW, Aladjem MI.
Circuit diagrams for biological networks.
Mol. Syst. Biol. 2: 2006.0002, 2006. [Journal]

5) Feng YQ, Desprat R, Fu H, Olivier E, Lin CM, Lobell A, Gowda SN, Aladjem MI, Bouhassira EE.
DNA methylation supports intrinsic epigenetic memory in mammalian cells.
PLoS Genet. 2: e65, 2006. [Journal]

6) Fu H, Wang L, Lin CM, Singhania S, Bouhassira EE, Aladjem MI.
Preventing gene silencing with human replicators.
Nat. Biotechnol. 24: 572-6, 2006. [Journal]

7) Wang L, Lin CM, Lopreiato JO, Aladjem MI.
Cooperative sequence modules determine replication initiation sites at the human {beta}-globin locus.
Hum. Mol. Genet. 15: 2613-22, 2006. [Journal]

8) Feng YQ, Warin R, Li T, Olivier E, Besse A, Lobell A, Fu H, Lin CM, Aladjem MI, Bouhassira EE.
The human beta-globin locus control region can silence as well as activate gene expression.
Mol Cell Biol. 25: 3864-74, 2005. [Journal]

9) Wang L, Lin CM, Brooks S, Cimbora D, Groudine M, Aladjem MI.
The human beta-globin replication initiation region consists of two modular independent replicators.
Mol Cell Biol. 24: 3373-86, 2004. [Journal]

10) Lin CM, Fu H, Martinovsky M, Bouhassira E, Aladjem MI.
Dynamic Alterations of Replication Timing in Mammalian Cells.
Current Biology. 13: 1019-28, 2003. [Journal]

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This page was last updated on 8/24/2009.