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Our Science – Pommier Website

Yves Pommier, M.D., Ph.D.

Selected Publications

1)  Singhal G, Leo E, Setty SK, Pommier Y, Thimmapaya B.
Adenovirus E1A oncogene induces rereplication of cellular DNA and alters DNA replication dynamics.
J. Virol. 87: 8767-78, 2013.
2)  Nomura W, Aikawa H, Ohashi N, Urano E, Métifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, Murakami T, Tamamura H.
Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Products.
ACS Chem. Biol. 2013.
3)  Métifiot M, Marchand C, Pommier Y.
HIV Integrase Inhibitors: 20-Year Landmark and Challenges.
Adv. Pharmacol. 67: 75-105, 2013.
4)  Sobek S, Dalla Rosa I, Pommier Y, Bornholz B, Kalfalah F, Zhang H, Wiesner RJ, von Kleist-Retzow JC, Hillebrand F, Schaal H, Mielke C, Christensen MO, Boege F.
Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I.
Nucleic Acids Res. 2013.
5)  Taliani S, Pugliesi I, Barresi E, Salerno S, Marchand C, Agama K, Simorini F, La Motta C, Marini AM, Di Leva FS, Marinelli L, Cosconati S, Novellino E, Pommier Y, Di Santo R, Da Settimo F.
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors.
J. Med. Chem. 2013.
6)  Huang SY, Murai J, Dalla Rosa I, Dexheimer TS, Naumova A, Gmeiner WH, Pommier Y.
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.
Nucleic Acids Res. 2013.
7)  Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS.
The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology.
Cancer Res. 73: 4372-82, 2013.
8)  Johnson BC, Métifiot M, Ferris A, Pommier Y, Hughes SH.
A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model.
J. Mol. Biol. 425: 2133-2146, 2013.
9)  Métifiot M, Maddali K, Johnson BC, Hare S, Smith SJ, Zhao XZ, Marchand C, Burke TR, Hughes SH, Cherepanov P, Pommier Y.
Activities, crystal structures, and molecular dynamics of dihydro-1H-isoindole derivatives, inhibitors of HIV-1 integrase.
ACS Chem. Biol. 8: 209-17, 2013.
10)  Pommier Y.
Drugging topoisomerases: lessons and challenges.
ACS Chem. Biol. 8: 82-95, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 9/6/2013.