Our Science – Pommier Website
Yves Pommier, M.D., Ph.D.
Selected Publications |
 |
| 1)
Johnson BC, Métifiot M, Ferris A, Pommier Y, Hughes SH. A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model. J. Mol. Biol. [Epub ahead of print], 2013. [Journal] |
|
| 2)
Métifiot M, Maddali K, Johnson BC, Hare S, Smith SJ, Zhao XZ, Marchand C, Burke TR, Hughes SH, Cherepanov P, Pommier Y. Activities, crystal structures, and molecular dynamics of dihydro-1H-isoindole derivatives, inhibitors of HIV-1 integrase. ACS Chem. Biol. 8: 209-17, 2013. [Journal] |
|
| 3)
Pommier Y. Drugging topoisomerases: lessons and challenges. ACS Chem. Biol. 8: 82-95, 2013. [Journal] |
|
| 4)
Fatoba ST, Tognetti S, Berto M, Leo E, Mulvey CM, Godovac-Zimmermann J, Pommier Y, Okorokov AL. Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation. Nucleic Acids Res. 41: 4065-79, 2013. [Journal] |
|
| 5)
Conda-Sheridan M, Reddy PV, Morrell A, Cobb BT, Marchand C, Agama K, Chergui A, Renaud A, Stephen AG, Bindu LK, Pommier Y, Cushman M. Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1). J. Med. Chem. 56: 182-200, 2013. [Journal] |
|
| 6)
Sirivolu VR, Vernekar SK, Marchand C, Naumova A, Chergui A, Renaud A, Stephen AG, Chen F, Sham YY, Pommier Y, Wang Z. 5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I. J. Med. Chem. 55: 8671-84, 2012. [Journal] |
|
| 7)
Zhao XZ, Maddali K, Smith SJ, Métifiot M, Johnson BC, Marchand C, Hughes SH, Pommier Y, Burke TR. 6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors. Bioorg. Med. Chem. Lett. 22: 7309-13, 2012. [Journal] |
|
| 8)
Seol Y, Zhang H, Pommier Y, Neuman KC. A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 109: 16125-30, 2012. [Journal] |
|
| 9)
Kiselev E, Agama K, Pommier Y, Cushman M. Azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents: a systematic study of structure-activity relationships. J. Med. Chem. 55: 1682-97, 2012. [Journal] |
|
| 10)
Zhao XZ, Maddali K, Metifiot M, Smith SJ, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR. Bicyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors. Chem Biol Drug Des. 79: 157-65, 2012. [Journal] |
|
| Click Here to View Expanded Bibliography. |
This page was last updated on 4/26/2013.
