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Kyung S. Lee, Ph.D.

Selected Publications

1)  Kang YH, Park JE, Yu LR, Soung NK, Yun SM, Bang JK, Seong YS, Yu H, Garfield S, Veenstra TD, Lee KS.
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation.
Mol. Cell. 24: 409-22, 2006.
2)  Yun S, Moulaei T, Lim D, Bang JK, Park J, Shenoy SR, Liu F, Kang YH, Liao C, Soung N, Lee S, Yoon D, Lim Y, Lee D, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR, Yaffe MB, Wlodawer A, Lee KS.
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Nat. Struct. Mol. Biol. 16: 876-82, 2009.
3)  Soung NK, Park JE, Yu LR, Lee KH, Lee JM, Bang JK, Veenstra TD, Rhee K, Lee KS.
Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells.
Dev. Cell. 16: 539-50, 2009.
4)  Liu F, Park J, Qian W, Lim D, Graber M, Berg T, Yaffe MB, Lee KS, Burke TR.
Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel.
Nat. Chem. Biol. 7: 595-601, 2011.
5)  Park S, Park J, Kim T, Kim J, Kwak M, Ku B, Tian L, Murugan R, Ahn M, Komiya S, Hojo H, Kim N, Kim B, Bang J, Erikson R, Lee K, Kim S, Oh B, Yang W, Lee K.
Molecular basis for unidirectional scaffold switching of Plk4 in centriole biogenesis.
Nat Struct Mol Biol. 2014.
In Press. [Journal]
6)  Zou J, Rezvani K, Wang H, Lee KS, Zhang D.
BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress.
Cell Cycle. 12: 2255-65, 2013.
7)  Qian W, Park J, Liu F, Lee KS, Burke TR.
Effects on polo-like kinase 1 polo-box domain binding affinities of peptides incurred by structural variation at the phosphoamino acid position.
Bioorg Med Chem. 21: 3996-4003, 2013.
8)  Chang J, Seo SG, Lee KH, Nagashima K, Bang JK, Kim BY, Erikson RL, Lee KW, Lee HJ, Park JE, Lee KS.
Essential role of Cenexin1, but not Odf2, in ciliogenesis.
Cell Cycle. 12: 655-62, 2013.
9)  González-Sancho JM, Greer YE, Abrahams CL, Takigawa Y, Baljinnyam B, Lee KH, Lee KS, Rubin JS, Brown AM.
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
J. Biol. Chem. 288: 9428-37, 2013.
10)  Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS.
Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.
Proc. Natl. Acad. Sci. U.S.A. 110: E4849-57, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 7/11/2014.