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Our Science – Gonzalez Website

Frank J. Gonzalez, Ph.D.

Selected Publications

1)  Yao PL, Morales JL, Zhu B, Kang BH, Gonzalez FJ, Peters JM.
Activation of Peroxisome Proliferator-Activated Receptor-ß/d (PPAR-ß/d) Inhibits Human Breast Cancer Cell Line Tumorigenicity.
Mol. Cancer Ther. 13: 1008-17, 2014.
2)  Koh KH, Pan X, Shen H, Arnold SL, Yu A, Gonzalez FJ, Isoherranen N, Jeong H.
Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice.
J. Biol. Chem. 289: 3105-13, 2014.
3)  Qi Y, Jiang C, Cheng J, Krausz KW, Li T, Ferrell JM, Gonzalez FJ, Chiang JY.
Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.
Biochim. Biophys. Acta. 2014.
4)  Manna SK, Tanaka N, Krausz KW, Haznadar M, Xue X, Matsubara T, Bowman ED, Fearon ER, Harris CC, Shah YM, Gonzalez FJ.
Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans.
Gastroenterology. 146: 1313-24, 2014.
5)  Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C.
Bisphenol A Increases Atherosclerosis in Pregnane X Receptor-Humanized ApoE Deficient Mice.
J Am Heart Assoc. 3: e000492, 2014.
6)  Jennings BL, George LW, Pingili AK, Khan NS, Estes AM, Fang XR, Gonzalez FJ, Malik KU.
Estrogen Metabolism by Cytochrome P450 1B1 Modulates the Hypertensive Effect of Angiotensin II in Female Mice.
Hypertension. 64: 134-40, 2014.
7)  Liu A, Krausz KW, Fang Z, Brocker C, Qu A, Gonzalez FJ.
Gemfibrozil disrupts lysophosphatidylcholine and bile acid homeostasis via PPARalpha and its relevance to hepatotoxicity.
Arch. Toxicol. 88: 983-96, 2014.
8)  Kim J, Qu A, Reddy JK, Gao B, Gonzalez FJ.
Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3.
Hepatology. 59: 695-704, 2014.
9)  Matsusue K, Aibara D, Hayafuchi R, Matsuo K, Takiguchi S, Gonzalez FJ, Yamano S.
Hepatic PPAR? and LXRa independently regulate lipid accumulation in the livers of genetically obese mice.
FEBS Lett. 588: 2277-81, 2014.
10)  Bonzo JA, Brocker C, Jiang C, Wang RH, Deng CX, Gonzalez FJ.
Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-a function in vivo.
Am. J. Physiol. Endocrinol. Metab. 306: E824-37, 2014.
Click Here to View Expanded Bibliography.

This page was last updated on 7/15/2014.