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Our Science – Wickner Website

Sue Wickner, Ph.D.

Selected Publications

1)  Doyle SM, Genest O, Wickner S.
Protein rescue from aggregates by powerful molecular chaperone machines.
Nat. Rev. Mol. Cell Biol. 14: 617-29, 2013.
2)  Genest O, Reidy M, Street TO, Hoskins JR, Camberg JL, Agard DA, Masison DC, Wickner S.
Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast.
Mol. Cell. 49: 464-73, 2013.
3)  Doyle SM, Hoskins JR, Wickner S.
DnaK-dependent disaggregation by Caseinolytic Peptidase B, ClpB, mutants reveals functional overlap in the N-terminal domain and nucleotide-binding domain-1 pore tyrosine.
J Biol Chem. 287: 28470-9, 2012.
4)  Zhang T, Ploetz EA, Nagy M, Doyle SM, Wickner S, Smith PE, Zolkiewski M.
Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency.
Proteins. 80: 2758-68, 2012.
5)  Reidy M, Miot M, Masison DC.
Prokaryotic Chaperones Support Yeast Prions and Thermotolerance and Define Disaggregation Machinery Interactions.
Genetics. 192: 185-93, 2012.
6)  Camberg JL, Wickner S.
Regulated proteolysis as a force to control the cell cycle.
Structure. 20: 1128-30, 2012.
7)  Evans ML, Schmidt JC, Ilbert M, Doyle SM, Quan S, Bardwell JC, Jakob U, Wickner S, Chapman MR.
E. coli chaperones DnaK, Hsp33 and Spy inhibit bacterial functional amyloid assembly.
Prion. 5: 323-34, 2011.
8)  Genest O, Hoskins JR, Camberg JL, Doyle SM, Wickner S.
Heat shock protein 90 from Escherichia coli collaborates with the DnaK chaperone system in client protein remodeling.
Proc. Natl. Acad. Sci. U.S.A. 108: 8206-11, 2011.
9)  Miot M, Reidy M, Doyle SM, Hoskins JR, Johnston DM, Genest O, Vitery MC, Masison DC, Wickner S.
Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.
Proc. Natl. Acad. Sci. U.S.A. 108: 6915-20, 2011.
10)  Camberg JL, Hoskins JR, Wickner S.
The interplay of ClpXP with the cell division machinery in Escherichia coli.
J. Bacteriol. 193: 1911-8, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 12/12/2013.