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Our Science – Wickner Website

Sue Wickner, Ph.D.

Selected Publications

1)  Doyle SM, Genest O, Wickner S.
Protein rescue from aggregates by powerful molecular chaperone machines.
Nat. Rev. Mol. Cell Biol. 14: 617-29, 2013.
[Journal]
2)  Genest O, Reidy M, Street TO, Hoskins JR, Camberg JL, Agard DA, Masison DC, Wickner S.
Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast.
Mol. Cell. 49: 464-73, 2013.
[Journal]
3)  Miot M, Reidy M, Doyle SM, Hoskins JR, Johnston DM, Genest O, Vitery MC, Masison DC, Wickner S.
Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.
Proc. Natl. Acad. Sci. U.S.A. 108: 6915-20, 2011.
[Journal]
4)  Genest O, Hoskins JR, Camberg JL, Doyle SM, Wickner S.
Heat shock protein 90 from Escherichia coli collaborates with the DnaK chaperone system in client protein remodeling.
Proc. Natl. Acad. Sci. U.S.A. 108: 8206-11, 2011.
[Journal]
5)  Camberg JL, Hoskins JR, Wickner S.
ClpXP protease degrades the cytoskeletal protein, FtsZ, and modulates FtsZ polymer dynamics.
Proc. Natl. Acad. Sci. U.S.A. 106(26): 10614-9, 2009.
[Journal]
6)  Camberg JL, Viola MG, Rea L, Hoskins JR, Wickner S.
Location of dual sites in E. coli FtsZ important for degradation by ClpXP; one at the C-terminus and one in the disordered linker.
PLoS ONE. 9: e94964, 2014.
[Journal]
7)  Battesti A, Hoskins JR, Tong S, Milanesio P, Mann JM, Kravats A, Tsegaye YM, Bougdour A, Wickner S, Gottesman S.
Anti-adaptors provide multiple modes for regulation of the RssB adaptor protein.
Genes Dev. 27: 2722-35, 2013.
[Journal]
8)  Markovski M, Wickner S.
Preventing bacterial suicide: a novel toxin-antitoxin strategy.
Mol. Cell. 52: 611-2, 2013.
[Journal]
9)  Doyle SM, Hoskins JR, Wickner S.
DnaK-dependent disaggregation by Caseinolytic Peptidase B, ClpB, mutants reveals functional overlap in the N-terminal domain and nucleotide-binding domain-1 pore tyrosine.
J Biol Chem. 287: 28470-9, 2012.
[Journal]
10)  Zhang T, Ploetz EA, Nagy M, Doyle SM, Wickner S, Smith PE, Zolkiewski M.
Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency.
Proteins. 80: 2758-68, 2012.
[Journal]
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This page was last updated on 6/19/2014.