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Our Science – Restifo Website

Nicholas P. Restifo, M.D.

Selected Publications

1)  Abate-Daga D, Lagisetty KH, Tran E, Zheng Z, Gattinoni L, Yu Z, Burns WR, Miermont AM, Teper Y, Rudloff U, Restifo NP, Feldman SA, Rosenberg SA, Morgan RA.
A Novel Chimeric Antigen Receptor Against Prostate Stem Cell Antigen Mediates Tumor Destruction in a Humanized Mouse Model of Pancreatic Cancer.
Hum. Gene Ther. [Epub ahead of print], 2014.
[Journal]
2)  Farber DL, Yudanin NA, Restifo NP.
Human memory T cells: generation, compartmentalization and homeostasis.
Nat. Rev. Immunol. 14: 24-35, 2014.
[Journal]
3)  Crompton JG, Clever D, Vizcardo R, Rao M, Restifo NP.
Reprogramming antitumor immunity.
Trends Immunol. 35: 178-85, 2014.
[Journal]
4)  Church SE, Jensen SM, Antony PA, Restifo NP, Fox BA.
Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells.
Eur. J. Immunol. 44: 69-79, 2014.
[Journal]
5)  Crompton JG, Sukumar M, Restifo NP.
Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy.
Immunol. Rev. 257: 264-76, 2014.
[Journal]
6)  Restifo NP.
A "big data" view of the tumor "immunome".
Immunity. 39: 631-2, 2013.
[Journal]
7)  Roychoudhuri R, Hirahara K, Mousavi K, Clever D, Klebanoff CA, Bonelli M, Sciumè G, Zare H, Vahedi G, Dema B, Yu Z, Liu H, Takahashi H, Rao M, Muranski P, Crompton JG, Punkosdy G, Bedognetti D, Wang E, Hoffmann V, Rivera J, Marincola FM, Nakamura A, Sartorelli V, Kanno Y, Gattinoni L, Muto A, Igarashi K, O'Shea JJ, Restifo NP.
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.
Nature. 498: 506-10, 2013.
[Journal]
8)  Morgan RA, Chinnasamy N, Abate-Daga D, Gros A, Robbins PF, Zheng Z, Dudley ME, Feldman SA, Yang JC, Sherry RM, Phan GQ, Hughes MS, Kammula US, Miller AD, Hessman CJ, Stewart AA, Restifo NP, Quezado MM, Alimchandani M, Rosenberg AZ, Nath A, Wang T, Bielekova B, Wuest SC, Akula N, McMahon FJ, Wilde S, Mosetter B, Schendel DJ, Laurencot CM, Rosenberg SA.
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
J. Immunother. 36: 133-51, 2013.
[Journal]
9)  Kerkar SP, Leonardi AJ, van Panhuys N, Zhang L, Yu Z, Crompton JG, Pan JH, Palmer DC, Morgan RA, Rosenberg SA, Restifo NP.
Collapse of the Tumor Stroma is Triggered by IL-12 Induction of Fas.
Mol. Ther. 21: 1369-77, 2013.
[Journal]
10)  Hanada K, Restifo NP.
Double or nothing on cancer immunotherapy.
Nat. Biotechnol. 31: 33-4, 2013.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 5/15/2014.