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Our Science – Qasba Website

Pradman K. Qasba, Ph.D.

Selected Publications

1)  Mercer N, Ramakrishnan B, Boeggeman E, Verdi L, Qasba PK.
Use of novel mutant galactosyltransferase for the bioconjugation of terminal N-acetylglucosamine (GlcNAc) residues on live cell surface.
Bioconjug. Chem. 24: 144-52, 2013.
[Journal]
2)  Ramakrishnan B, Qasba P.
In vitro Folding of beta-1,4Galactosyltransferase and Polypeptide-alpha-N-acetylgalactosaminyltransferase from the Inclusion Bodies. In: Methods in Molecular Biology -Glycosyltransferases: Methods and Protocols.
Springer Science, Humana Press; 2012. In Press. [Book Chapter]
3)  Ramakrishnan B, Boeggeman E, Qasba PK.
Binding of GlcNAc beta1-6 branched oligosaccharide acceptors to beta4galactosyltransferase I reveal a new ligand binding mode.
J Biol Chem. 287: 28666-74, 2012.
[Journal]
4)  Pasek M, Ramakrishnan B, Boeggeman E, Mercer N, Dulcey AE, Griffiths GL, Qasba PK.
The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.
Glycobiology. 22: 379-88, 2012.
[Journal]
5)  Mercer N, Ramakrishnan B, Boeggeman E, Qasba PK.
Applications of site-specific labeling to study HAMLET, a tumoricidal complex of alpha-lactalbumin and oleic acid.
PLoS ONE. 6: e26093, 2011.
[Journal]
6)  Ramakrishnan B, Boeggeman E, Pasek M, Qasba PK.
Bioconjugation Using Mutant Glycosyltransferases for the Site-Specific Labeling of Biomolecules with Sugars Carrying Chemical Handles.
Methods Mol Biol. 751: 281-296, 2011.
[Journal]
7)  Dulcey AE, Qasba PK, Lamb J, Griffiths GL.
Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferases.
Tetrahedron. 67: 2013-2017, 2011.
[Journal]
8)  Ramakrishnan B, Qasba PK.
Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
J. Biol. Chem. 285 (20): 15619-26, 2010.
[Journal]
9)  Pasek M, Boeggeman E, Ramakrishnan B, Qasba PK.
Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli.
Biochem. Biophys. Res. Commun. 394: 679-84, 2010.
[Journal]
10)  Ramakrishnan B, Qasba PK.
Structure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate beta1,4-galactosyltransferase, invertebrate beta1,4-N-acetylgalactosaminyltransferase and alpha-polypeptidyl-N-acetylgalactosaminyltransferase.
Curr. Opin. Struct. Biol. 20: 536-42, 2010.
[Journal]
11)  Pasek M, Ramakrishnan B, Boeggeman E, Manzoni M, Waybright TJ, Qasba PK.
Bioconjugation and Detection of Lactosamine Moiety using alpha1,3-Galactosyltransferase Mutants That Transfer C2-Modified Galactose with a Chemical Handle.
Bioconjug. Chem. 20(3): 608-18, 2009.
[Journal]
12)  Brown JR, Yang F, Sinha A, Ramakrishnan B, Tor Y, Qasba PK, Esko JD.
Deoxygenated Disaccharide Analogs as Specific Inhibitors of {beta}1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis.
J. Biol. Chem. 284: 4952-4959, 2009.
[Journal]
13)  Schuyler AD, Jernigan RL, Qasba PK, Ramakrishnan B, Chirikjian GS.
Iterative cluster-NMA: A tool for generating conformational transitions in proteins.
Proteins. 74: 760-76, 2009.
[Journal]
14)  Ramakrishnan B, Boeggeman E, Manzoni M, Zhu Z, Loomis K, Puri A, Dimitrov DS, Qasba PK.
Multiple site-specific in vitro labeling of single-chain antibody.
Bioconjug. Chem. 20(7): 1383-9, 2009.
[Journal]
15)  Boeggeman E, Ramakrishnan B, Pasek M, Manzoni M, Puri A, Loomis KH, Waybright TJ, Qasba PK.
Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection.
Bioconjug. Chem. 20 (6): 1228-36, 2009.
[Journal]
16)  Ramakrishnan B, Boeggeman E, Qasba PK.
Applications of glycosyltransferases in the site-specific conjugation of biomolecules and the development of a targeted drug delivery system and contrast agents for MRI.
Expert Opin Drug Deliv. 5: 149-153, 2008.
[Journal]
17)  Qasba PK, Boeggeman E, Ramakrishnan B.
Site-Specific Linking of Biomolecules via Glycan Residues Using Glycosyltransferases.
Biotechnol. Prog. 24(3): 520-6, 2008.
[Journal]
18)  Qasba PK, Ramakrishnan B, Boeggeman E.
Structure and function of beta -1,4-galactosyltransferase.
Current drug targets. 9: 292-309, 2008.
[Journal]
19)  Qasba P, Ramakrishnan B.
Boons G, Lee Y, Suzuki A, Taniguchi N, Voragen A, eds.
X-ray crystal structures of glycosyltransferases. In: Comprehensive Glycosciences: From Chemistry to Systems Biology.
Burlington, MA: Elsevier Ltd.; 2007. p. 251-281 [Book Chapter]
20)  Qasba PK, Ramakrishnan B.
Catalytic domains of glycosyltransferases with.
Glycobiology. 17(5): 7G-9G, 2007.
[Journal]
21)  Boeggeman E, Ramakrishnan B, Kilgore C, Khidekel N, Hsieh-Wilson LC, Simpson JT, Qasba PK.
Direct Identification of Nonreducing GlcNAc Residues on N-Glycans of Glycoproteins Using a Novel Chemoenzymatic Method.
Bioconjug Chem. 3: 806-14, 2007.
[Journal]
22)  Ramakrishnan B, Boeggeman E, Qasba PK.
Novel Method for in Vitro O-Glycosylation of Proteins: Application for Bioconjugation.
Bioconjug Chem. 18(6): 1912-8, 2007.
[Journal]
23)  Ramakrishnan B, Qasba PK.
Role of a single amino acid in the evolution of glycans of invertebrates and vertebrates.
J. Mol. Biol. 365: 570-6, 2007.
[Journal]
24)  Qasba PK, Ramakrishnan B, Boeggeman E.
Mutant glycosyltransferases assist in the development of a targeted drug delivery system and contrast agents for MRI.
AAPS J. 8(1): E190-5, 2006.
[Journal]
25)  Ramakrishnan B, Ramasamy V, Qasba PK.
Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J Mol Biol. 357(5): 1619-33, 2006.
[Journal]
26)  Ramakrishnan B, Boeggeman E, Qasba PK.
Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I(,)(,).
Biochemistry. 44: 3202-10, 2005.
[Journal]
27)  Ramasamy V, Ramakrishnan B, Boeggeman E, Ratner DM, Seeberger PH, Qasba PK.
Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety.
J Mol Biol. 353: 53-67, 2005.
[Journal]
28)  Qasba PK, Ramakrishnan B, Boeggeman E.
Substrate-induced conformational changes in glycosyltransferases.
Trends Biochem Sci. 30: 53-62, 2005.
[Journal]
29)  Ramakrishnan B, Boeggeman E, Qasba PK.
Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose.
Biochemistry. 43: 12513-12522, 2004.
[Journal]
30)  Ramakrishnan B, Boeggeman E, Ramasamy V, Qasba PK.
Structure and catalytic cycle of beta-1,4-galactosyltransferase.
Curr Opin Struct Biol. 14 (5): 593-600, 2004.
[Journal]
31)  Khidekel N, Arndt S, Lamarre-Vincent N, Lippert A, Poulin-Kerstien KG, Ramakrishnan B, Qasba PK, Hsieh-Wilson LC.
A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications.
J Am Chem Soc. 125: 16162-3, 2003.
[Journal]
32)  Ramakrishnan B, Qasba PK.
Comparison of the closed conformation of the beta 1,4-galactosyltransferase-1 (beta 4Gal-T1) in the presence and absence of alpha-lactalbumin (LA).
J Biomol Struct Dyn. 21: 1-8, 2003.
[Journal]
33)  Gunasekaran K, Ma B, Ramakrishnan B, Qasba PK, Nussinov R.
Interdependence of backbone flexibility, residue conservation, and enzyme function: a case study on beta1,4-galactosyltransferase-I.
Biochemistry. 42: 3674-87, 2003.
[Journal]
34)  Boeggeman EE, Ramakrishnan B, Qasba PK.
The N-terminal stem region of bovine and human beta1,4-galactosyltransferase I increases the in vitro folding efficiency of their catalytic domain from inclusion bodies.
Protein Expr Purif. 30: 219-29, 2003.
[Journal]
35)  Ramasamy V, Ramakrishnan B, Boeggeman E, Qasba PK.
The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I.
J Mol Biol. 331: 1065-76, 2003.
[Journal]
36)  Ramakrishnan B, Boeggeman E, Qasba PK.
Beta-1,4-galactosyltransferase and lactose synthase: molecular mechanical devices.
Biochem Biophys Res Commun. 291: 1113-8, 2002.
[Journal]
37)  Ramakrishnan B, Balaji PV, Qasba PK.
Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site.
J Mol Biol. 318: 491-502, 2002.
[Journal]
38)  Ramakrishnan B, Qasba PK.
Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity.
J Biol Chem. 277: 20833-9, 2002.
[Journal]
39)  Boeggeman E, Qasba PK.
Studies on the metal binding sites in the catalytic domain of beta1,4-galactosyltransferase.
Glycobiology. 12: 395-407, 2002.
[Journal]
40)  Ramakrishnan B, Shah PS, Qasba PK.
alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.
J Biol Chem. 276: 37665-71, 2001.
[Journal]
41)  Ramakrishnan B, Qasba PK.
Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I.
J Mol Biol. 310: 205-18, 2001.
[Journal]
42)  Shah PS, Bizik F, Dukor RK, Qasba PK.
Active site studies of bovine alpha1-->3-galactosyltransferase and its secondary structure prediction.
Biochim Biophys Acta. 1480: 222-34, 2000.
[Journal]
43)  Qasba PK.
Involvement of sugars in protein-protein interactions.
J. Carbohydrate Polymers. 41: 293-309, 2000.
[Journal]
44)  Iyer LK, Qasba PK.
Molecular dynamics simulation of alpha-lactalbumin and calcium binding c-type lysozyme.
Protein Eng. 12: 129-39, 1999.
[Journal]
45)  Rao V, Qasba P, Balaji P, Chandrasekaran R.
Conformation of Carbohydrates.
Amsterdam: Harwood Academic Publishers; 1998. [Book]
46)  Rao VS, Lam K, Qasba PK.
Architecture of the sugar binding sites in carbohydrate binding proteins--a computer modeling study.
Int J Biol Macromol. 23: 295-307, 1998.
[Journal]
47)  Lam K, Rao VS, Qasba PK.
Molecular modeling studies on binding of bFGF to heparin and its receptor FGFR1.
J Biomol Struct Dyn. 15: 1009-27, 1998.
[Journal]
48)  Rao VS, Lam K, Qasba PK.
Three dimensional structure of the soybean agglutinin Gal/GalNAc complexes by homology modeling.
J Biomol Struct Dyn. 15: 853-60, 1998.
[Journal]
49)  Qasba PK, Balaji PV, Rao VSR.
Conformational analysis of Asn-linked oligosaccharides: implications in biological processes.
J. Mol. Struct. (Theochem). 395-396: 333-60, 1997.
[Journal]
50)  Qasba PK, Kumar S.
Molecular divergence of lysozymes and alpha-lactalbumin.
Crit Rev Biochem Mol Biol. 32: 255-306, 1997.
[Journal]
51)  Balaji PV, Qasba PK, Rao VS.
Molecular dynamics simulations of hybrid and complex type oligosaccharides.
Int J Biol Macromol. 18: 101-14, 1996.
[Journal]
52)  Rao VS, Balaji PV, Qasba PK.
Controversial iduronate ring conformation in dermatan sulphate.
Glycobiology. 5: 273-9, 1995.
[Journal]
53)  Boeggeman EE, Balaji PV, Qasba PK.
Functional domains of bovine beta-1,4 galactosyltransferase.
Glycoconj J. 12: 865-78, 1995.
[Journal]
54)  Escalante C, Qasba PK, Yang DC.
Expression of human aspartyl-tRNA synthetase in COS cells.
Mol Cell Biochem. 140: 55-63, 1994.
[Journal]
55)  Balaji PV, Qasba PK, Rao VS.
Molecular dynamics simulations of high-mannose oligosaccharides.
Glycobiology. 4: 497-515, 1994.
[Journal]
56)  Qasba PK, Balaji PV, Rao VS.
Molecular dynamics simulations of oligosaccharides and their conformation in the crystal structure of lectin-carbohydrate complex: importance of the torsion angle psi for the orientation of alpha 1,6-arm.
Glycobiology. 4: 805-15, 1994.
[Journal]
57)  Boeggeman EE, Balaji PV, Sethi N, Masibay AS, Qasba PK.
Expression of deletion constructs of bovine beta-1,4-galactosyltransferase in Escherichia coli: importance of Cys134 for its activity.
Protein Eng. 6: 779-85, 1993.
[Journal]
58)  Balaji PV, Qasba PK, Rao VS.
Molecular dynamics simulations of asialoglycoprotein receptor ligands.
Biochemistry. 32: 12599-611, 1993.
[Journal]
59)  Masibay AS, Balaji PV, Boeggeman EE, Qasba PK.
Mutational analysis of the Golgi retention signal of bovine beta-1,4-galactosyltransferase.
J Biol Chem. 268: 9908-16, 1993.
[Journal]
60)  Qasba PK, Masibay AS, Boeggeman EE, Balaji PV.
Study of the functional domains of beta-1-4galactosyltransferase through the expression of the deletion constructs of cDNA in E. coli and mammalian cells: Disulfide bond between Cys124 and Cys247 is required for the folding and enzyme activity while the transmembrane domain is essential for stable expression in mammalian cells.
Protein Engineering Supplement. 6: 99, 1993.
[Journal]
61)  Masibay AS, Boeggeman E, Qasba PK.
Deletion analysis of the NH2-terminal region of beta-1,4-galactosyltransferase.
Mol Biol Rep. 16: 99-104, 1992.
[Journal]
62)  Masibay AS, Damewood GP, Boeggeman E, Qasba PK.
Expression of beta-1,4-galactosyltransferase gene during 3T3 cell growth.
Biochim Biophys Acta. 1090: 230-4, 1991.
[Journal]
63)  Boeggeman E, Masibay AS, Qasba PK, Sreevalsan T.
Identification and partial characterization of genes that are transactivated by different pathways in quiescent mouse cells stimulated with serum.
J Cell Physiol. 145: 286-94, 1990.
[Journal]
64)  Masibay AS, Qasba PK.
Expression of bovine beta-1,4-galactosyltransferase cDNA in COS-7 cells.
Proc Natl Acad Sci U S A. 86: 5733-7, 1989.
[Journal]
65)  Oka K, Yuan JG, Senda M, Masibay AS, Qasba PK, Masuno H, Scow RO, Paterniti JR, Brown WV, Oasba PK.
Expression of lipoprotein lipase gene in combined lipase deficiency.
Biochim Biophys Acta. 1008: 351-4, 1989.
[Journal]
66)  Masibay AS, Qasba PK.
The complex alternative processing of the beta-1-4galactosyltransferasae precusor mRNA.
J. Cell Biology. 4842: 850a, 1989.
[Journal]
67)  Masibay AS, Qasba PK, Sengupta DN, Damewood GP, Sreevalsan T.
Cell-cycle-specific and serum-dependent expression of gamma-actin mRNA in Swiss mouse 3T3 cells.
Mol Cell Biol. 8: 2288-94, 1988.
[Journal]
68)  Nicholas KR, Sankaran L, Kulski JK, Chomczynski P, Qasba P.
Comparison of some biological effects of epidermal growth factor and commercial serum albumin on the induction of alpha-lactalbumin in rat and rabbit mammary explants.
J. Endocrinol. 119: 133-39, 1988.
[Journal]
69)  Ziska SE, Bhattacharjee M, Herber RL, Qasba PK, Vonderhaar BK.
Thyroid hormone regulation of alpha-lactalbumin: differential glycosylation and messenger ribonucleic acid synthesis in mouse mammary glands.
Endocrinology. 123: 2242-8, 1988.
[Journal]
70)  Nieto A, Qasba PK, Nakhasi HL, Dhar R.
Differential regulation of c-Ha-ras and c-Ki-ras gene expression in rat mammary gland.
Carcinogenesis. 8: 1955-8, 1987.
[Journal]
71)  Senda M, Oka K, Brown WV, Qasba PK, Furuichi Y.
Molecular cloning and sequence of a cDNA coding for bovine lipoprotein lipase.
Proc Natl Acad Sci U S A. 84: 4369-73, 1987.
[Journal]
72)  Narimatsu H, Sinha S, Brew K, Okayama H, Qasba PK.
Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.
Proc Natl Acad Sci U S A. 83: 4720-4, 1986.
[Journal]
73)  Daruwalla KR, Nakhasi HL, Qasba PK.
Galactosyltransferase purified from rat milk is distinct from the human and bovine enzyme.
J Dairy Sci. 69: 1806-10, 1986.
[Journal]
74)  Topper YJ, Sankaran L, Chomczynski P, Prosser C, Qasba P.
Three stages of responsiveness to hormones in the mammary cell.
NY Acad of Sci. 464: 1-10, 1986.
[Journal]
75)  Chomczynski P, Qasba PK.
Alkaline transfer of DNA to GeneScreenPlus membrane.
NEN Product News. 4: 2, 1984.
[Journal]
76)  Chomczynski P, Qasba PK.
Alkaline transfer of DNA to plastic membrane.
Biochem Biophys Res Commun. 122: 340-4, 1984.
[Journal]
77)  Byers SW, Dym M, Hewlett IK, Qasba PK.
Alpha-lactalbumin-like proteins in the male reproductive tract.
Ann N Y Acad Sci. 438: 8-17, 1984.
[Journal]
78)  Sankaran L, Qasba PK, Topper YJ.
Effects of estrogen-depletion on rate casein gene expression.
Biochem. Biophys. Res. Comm. 125: 682-89, 1984.
[Journal]
79)  Chomczynski P, Qasba PK, Topper Y.
Essential role of insulin in transcription of the rate 25,000 molecular weight casein gene.
Science. 226: 1326-28, 1984.
[Journal]
80)  Byers SW, Qasba PK, Paulson HL, Dym M.
Immunocytochemical localization of alpha-lactalbumin in the male reproductive tract.
Biol Reprod. 30: 171-8, 1984.
[Journal]
81)  Qasba PK, Safaya SK.
Similarity of the nucleotide sequences of rat alpha-lactalbumin and chicken lysozyme genes.
Nature. 308: 377-80, 1984.
[Journal]
82)  Kulski JK, Topper YJ, Chomczynski P, Qasba P.
An essential role for glucocorticoid in casein gene expression in rat mammary explants.
Biochem Biophys Res Comm. 114(1): 380-87, 1983.
[Journal]
83)  Kulski JK, Nicholas KR, Topper YJ, Qasba P.
Essentiality of insulin and prolactin for accumulation of rat casein mRNA.
Biochem. Biophys. Res. Comm. 116: 994-99, 1983.
[Journal]
84)  Horn TM, Sodroski J, Qasba PK.
Protein-coding capacities of polyadenylated RNAs from normal and neoplastic rat mammary tissues.
Cancer Res. 43: 1819-26, 1983.
[Journal]
85)  Qasba PK, Hewlett IK, Byers S.
The presence of the milk protein, alpha-lactalbumin and its mRNA in the rat epididymis.
Biochem Biophys Res Commun. 117: 306-12, 1983.
[Journal]
86)  Dandekar AM, Robinson EA, Appella E, Qasba PK.
Complete sequence analysis of cDNA clones encoding rat whey phosphoprotein: homology to a protease inhibitor.
Proc Natl Acad Sci U S A. 79: 3987-91, 1982.
[Journal]
87)  Qasba PK, Dandekar AM, Horn TM, Losonczy I, Siegel M, Sobiech KA, Nakhasi HL, Devinoy E.
Milk protein gene expression in the rat mammary gland.
Crit Rev Food Sci Nutr. 16: 165-86, 1982.
[Journal]
88)  Dandekar AM, Qasba PK.
Rat alpha-lactalbumin has a 17-residue-long COOH-terminal hydrophobic extension as judged by sequence analysis of the cDNA clones.
Proc Natl Acad Sci U S A. 78: 4853-7, 1981.
[Journal]
89)  Dandekar AM, Qasba PK.
Inverse relationship between expression of alpha-lactalbumin and methylation of its gene sequences in rat mammary gland and tumors.
Eur. J. Cell Biol. 22: 10, 1980.
[Journal]
90)  Nakhasi HL, Qasba PK.
Quantitation of milk proteins and their RNA's in rat mammary gland at various stages of gestation and lactation.
J. Biol. Chem. 254: 6016-25, 1979.
[Journal]
91)  Qasba PK, Nakhasi HL.
alpha-Lactalbumin mRNA in 4-day lactating rat mammary gland.
Proc Natl Acad Sci U S A. 75: 4739-43, 1978.
[Journal]
92)  Qasba PK, Chakrabartty PK.
Purification and properties of two forms of rat alpha-lactalbumin.
J Biol Chem. 253: 1167-73, 1978.
[Journal]
93)  Qasba PK, Gullino PM.
alpha-Lactalbumin content of rat mammary carcinomas and the effect of pituitary stimulation.
Cancer Res. 37: 3792-5, 1977.
[Journal]
94)  Chakrabartty PK, Qasba PK.
Partial purification of rat alpha-lactalbumin mRNA.
Nucleic Acids Res. 4: 2065-74, 1977.
[Journal]
95)  Aposhian HV, Thayer RE, Qasba PK.
Formation of nucleoprotein complexes between polyoma empty capsides and DNA.
J Virol. 15: 645-53, 1975.
[Journal]
96)  Qasba PK.
Synthesis of simian virus 40 DNA in isolated nuclei.
Biochem Biophys Res Commun. 60: 1338-44, 1974.
[Journal]
97)  Qasba PK.
Synthesis of simian virus 40 DNA in isolated nuclei.
Proc Natl Acad Sci U S A. 71: 1045-9, 1974.
[Journal]
98)  Aposhian HV, Qasba PK, Yelton DB, Pletsch QA, Sethi VS.
The polyoma pseudovirion--its properties, production, and use in transferring DNA to mouse and human cells.
Johns Hopkins Med J Suppl. 2: 35-45, 1973.
[Journal]
99)  Aposhian HV, Qasba PK, Osterman JV, Waddell A.
Polyoma pseudovirions: an experimental model for the development of DNA for gene therapy.
Fed Proc. 31: 1310-4, 1972.
[Journal]
100)  Qasba PK, Aposhian HV.
DNA and gene therapy: transfer of mouse DNA to human and mouse embryonic cells by polyoma pseudovirions.
Proc Natl Acad Sci U S A. 68: 2345-9, 1971.
[Journal]
101)  Thies H, Schönenberger H, Qasba PK.
[Adduct formation and dimerisation of alpha-piperidinoacetonitrile during conversion with n-butylmagnesium chloride. V. Conversion of alpha-aminonitriles.
Arch Pharm Ber Dtsch Pharm Ges. 302: 168-74, 1969.
[Journal]
102)  Thies H, Schönenberger H, Qasba PK.
[Conversions of aliphatic substituted alpha-aminonitriles with metallic sodium in toluol. VI. Conversion of alpha-aminonitriles.
Arch Pharm Ber Dtsch Pharm Ges. 302: 610-7, 1969.
[Journal]
103)  Thies H, Schönenberger H, Qasba PK.
[Dimer exchange products of aromatic substituted alpha-aminonitriles. VII. Conversion of alpha-aminonitriles.
Arch Pharm Ber Dtsch Pharm Ges. 302: 803-7, 1969.
[Journal]
104)  Thies H, Schönenberger H, Qasba PK.
[Dimerization of alpha-piperidinoacetonitrile with t-butylmagnesium chloride. IV. Conversion of alpha-aminonitriles.
Arch Pharm Ber Dtsch Pharm Ges. 302: 161-8, 1969.
[Journal]
105)  Thies H, Schönenberger H, Qasba PK.
[Reactions of alpha-aminonitrils with Grignard-compounds. 3. Conversion of alpha-aminonitrils. Effect of ramification degree and chain length on the reaction course.
Arch Pharm Ber Dtsch Pharm Ges. 302: 30-42, 1969.
[Journal]
106)  Seifert W, Qasba PK, Walter G, Palm P, Schachner M, Zillig W.
Kinetics of the alteration and modification of DNA-dependent RNA polymerase in T4 phage infected E. coli cells.
Eur. J. Biochem. 9: 319-24, 1969.
[Journal]
107)  Qasba PK, Zillig W.
Nature of RNA synthesized at low and high ionic strength by DNA-dependent RNA-polymerase from Escherichia coli.
Eur J Biochem. 7: 315-7, 1969.
[Journal]
108)  Thies H, Schonenberger H, Qasba PK.
Uber die Reaktionweise von a-aminoacetonitrilen mit metallishem Natrium in flussigem Ammoniak.
Archive der Pharmazie. 302: 897-900, 1969.
[Journal]
109)  Thies H, Schonenberger H, Qasba PK.
Reduction of a-amino nitriles with metallic sodium in Toluene.
Tetrahedron Lett. 3: 163-66, 1965.
[Journal]
110)  Thies H, Schonenberger H, Qasba PK.
Dimerization of piperidioneacetonitrile under the influence of Grignard Reagents.
Angewandte Chemie (International Editiion). 1: 660-61, 1962.
[Journal]
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This page was last updated on 4/26/2013.