Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health www.cancer.gov
CCR - For Our Staff| Home |

Our Science – Qasba Website

Pradman K. Qasba, Ph.D.

Selected Publications

1)  Mercer N, Ramakrishnan B, Boeggeman E, Verdi L, Qasba PK.
Use of novel mutant galactosyltransferase for the bioconjugation of terminal N-acetylglucosamine (GlcNAc) residues on live cell surface.
Bioconjug. Chem. 24: 144-52, 2013.
[Journal]
2)  Ramakrishnan B, Qasba P.
In vitro Folding of beta-1,4Galactosyltransferase and Polypeptide-alpha-N-acetylgalactosaminyltransferase from the Inclusion Bodies. In: Methods in Molecular Biology -Glycosyltransferases: Methods and Protocols.
Springer Science, Humana Press; 2012. In Press. [Book Chapter]
3)  Ramakrishnan B, Boeggeman E, Qasba PK.
Binding of GlcNAc beta1-6 branched oligosaccharide acceptors to beta4galactosyltransferase I reveal a new ligand binding mode.
J Biol Chem. 287: 28666-74, 2012.
[Journal]
4)  Pasek M, Ramakrishnan B, Boeggeman E, Mercer N, Dulcey AE, Griffiths GL, Qasba PK.
The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.
Glycobiology. 22: 379-88, 2012.
[Journal]
5)  Mercer N, Ramakrishnan B, Boeggeman E, Qasba PK.
Applications of site-specific labeling to study HAMLET, a tumoricidal complex of alpha-lactalbumin and oleic acid.
PLoS ONE. 6: e26093, 2011.
[Journal]
6)  Ramakrishnan B, Boeggeman E, Pasek M, Qasba PK.
Bioconjugation Using Mutant Glycosyltransferases for the Site-Specific Labeling of Biomolecules with Sugars Carrying Chemical Handles.
Methods Mol Biol. 751: 281-296, 2011.
[Journal]
7)  Dulcey AE, Qasba PK, Lamb J, Griffiths GL.
Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferases.
Tetrahedron. 67: 2013-2017, 2011.
[Journal]
8)  Ramakrishnan B, Qasba PK.
Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
J. Biol. Chem. 285 (20): 15619-26, 2010.
[Journal]
9)  Pasek M, Boeggeman E, Ramakrishnan B, Qasba PK.
Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli.
Biochem. Biophys. Res. Commun. 394: 679-84, 2010.
[Journal]
10)  Ramakrishnan B, Qasba PK.
Structure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate beta1,4-galactosyltransferase, invertebrate beta1,4-N-acetylgalactosaminyltransferase and alpha-polypeptidyl-N-acetylgalactosaminyltransferase.
Curr. Opin. Struct. Biol. 20: 536-42, 2010.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 4/26/2013.