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Our Science – Dimitrov Website

Dimiter S. Dimitrov, Ph.D.

Selected Publications

1)  Chen W, Gong R, Ying T, Prabakaran P, Zhu Z, Feng Y, Dimitrov DS.
Discovery of novel candidate therapeutics and diagnostics based on engineered human antibody domains.
Curr Drug Discov Technol. 11: 28-40, 2014.
2)  Chen W, Feng Y, Prabakaran P, Ying T, Wang Y, Sun J, Macedo CD, Zhu Z, He Y, Polonis VR, Dimitrov DS.
Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.
J. Virol. 88: 1125-39, 2014.
3)  Sun JY, Shen J, Thibodeaux J, Huang G, Wang Y, Gao J, Low PS, Dimitrov DS, Sumer BD.
In vivo optical imaging of folate receptor-ß in head and neck squamous cell carcinoma.
Laryngoscope. [Epub ahead of print], 2014.
4)  Ofek G, Zirkle B, Yang Y, Zhu Z, McKee K, Zhang B, Chuang GY, Georgiev IS, O'Dell S, Doria-Rose N, Mascola JR, Dimitrov DS, Kwong PD.
Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6.
J. Virol. 88: 2426-41, 2014.
5)  Tang Z, Feng M, Gao W, Phung Y, Chen W, Chaudhary A, Croix BS, Qian M, Dimitrov DS, Ho M.
A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface.
Mol. Cancer Ther. 12: 416-26, 2013.
6)  Broder CC, Xu K, Nikolov DB, Zhu Z, Dimitrov DS, Middleton D, Pallister J, Geisbert TW, Bossart KN, Wang LF.
A treatment for and vaccine against the deadly Hendra and Nipah viruses.
Antiviral Res. 100: 8-13, 2013.
7)  Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ.
Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia.
Blood. 121: 1165-74, 2013.
8)  Chen W, Ying T, Dimitrov DS.
Antibody-based candidate therapeutics against HIV-1: implications for virus eradication and vaccine design.
Expert Opin Biol Ther. 13: 657-71, 2013.
9)  Shingai M, Nishimura Y, Klein F, Mouquet H, Donau OK, Plishka R, Buckler-White A, Seaman M, Piatak M, Lifson JD, Dimitrov DS, Nussenzweig MC, Martin MA.
Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia.
Nature. 503: 277-80, 2013.
10)  Xu K, Rockx B, Xie Y, DeBuysscher BL, Fusco DL, Zhu Z, Chan YP, Xu Y, Luu T, Cer RZ, Feldmann H, Mokashi V, Dimitrov DS, Bishop-Lilly KA, Broder CC, Nikolov DB.
Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.
PLoS Pathog. 9: e1003684, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 4/25/2014.