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Our Science – Blumenthal Website

Robert Blumenthal, Ph.D.

Selected Publications

1)  Blumenthal R, Durell S, Viard M.
HIV viral entry and envelope glycoprotein mediated fusion.
J. Biol. Chem. 2012.
2)  Puri A, Jang H, Yavlovich A, Masood MA, Veenstra TD, Luna C, Aranda-Espinoza H, Nussinov R, Blumenthal R.
Material Properties of Matrix Lipids Determine the Conformation and Intermolecular Reactivity of Diacetylenic Phosphatidylcholine in the Lipid Bilayer.
Langmuir. 27: 15120-8, 2011.
3)  Gupta K, Jang H, Harlen K, Puri A, Nussinov R, Schneider JP, Blumenthal R.
Mechanism of Membrane Permeation Induced by Synthetic ß-Hairpin Peptides.
Biophys. J. 105: 2093-103, 2013.
4)  Raviv Y, Blumenthal R, Tompkins SM, Humberd J, Hogan RJ, Viard M.
Hydrophobic Inactivation of Influenza Viruses confers Preservation of Viral Structure with Enhanced Immunogenicity.
J. Virol. 82: 4612-4619, 2008.
5)  Gallo SA, Puri A, Blumenthal R.
HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process.
Biochemistry. 40: 12231-6, 2001.
6)  Afonin KA, Viard M, Martins AN, Lockett SJ, Maciag AE, Freed EO, Heldman E, Jaeger L, Blumenthal R, Shapiro BA.
Activation of different split functionalities on re-association of RNA-DNA hybrids.
Nat Nanotechnol. 8: 296-304, 2013.
7)  Afonin KA, Desai R, Viard M, Kireeva ML, Bindewald E, Case CL, Maciag AE, Kasprzak WK, Kim T, Sappe A, Stepler M, Kewalramani VN, Kashlev M, Blumenthal R, Shapiro BA.
Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities.
Nucleic Acids Res. 2013.
8)  Kim T, Afonin KA, Viard M, Koyfman AY, Sparks S, Heldman E, Grinberg S, Linder C, Blumenthal RP, Shapiro BA.
In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery.
Mol Ther Nucleic Acids. 2: e80, 2013.
9)  Yavlovich A, Viard M, Gupta K, Sine J, Vu M, Blumenthal R, Tata DB, Puri A.
Low-visibility light-intensity laser-triggered release of entrapped calcein from 1,2-bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine liposomes is mediated through a type I photoactivation pathway.
Int J Nanomedicine. 8: 2575-87, 2013.
10)  Reingewertz TH, Britan-Rosich E, Rotem-Bamberger S, Viard M, Jacobs A, Miller A, Lee JY, Hwang J, Blumenthal R, Kotler M, Friedler A.
Mapping the Vif-A3G interaction using peptide arrays: A basis for anti-HIV lead peptides.
Bioorg. Med. Chem. [Epub ahead of print], 2013.
11)  Sinthuvanich C, Veiga AS, Gupta K, Gaspar D, Blumenthal R, Schneider JP.
Anticancer beta-Hairpin Peptides: Membrane-Induced Folding Triggers Activity.
J. Am. Chem. Soc. 134: 6210-7, 2012.
12)  Lee JH, Oh H, Baxa U, Raghavan SR, Blumenthal R.
Biopolymer-connected liposome networks as injectable biomaterials capable of sustained local drug delivery.
Biomacromolecules. 13: 3388-94, 2012.
13)  Yavlovich A, Viard M, Zhou M, Veenstra TD, Wang JM, Gong W, Heldman E, Blumenthal R, Raviv Y.
Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4+ target cells.
Blood. 120: 1246-53, 2012.
14)  Reuven EM, Dadon Y, Viard M, Manukovsky N, Blumenthal R, Shai Y.
HIV-1 gp41 transmembrane domain interacts with the fusion peptide: implication in lipid mixing and inhibition of virus-cell fusion.
Biochemistry. 51: 2867-78, 2012.
15)  Belanger JM, Raviv Y, Viard M, Baxa U, Blumenthal R.
Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: Towards a novel vaccine strategy.
Virol J. 9: 72, 2012.
16)  Ashkenazi A, Viard M, Unger L, Blumenthal R, Shai Y.
Sphingopeptides: dihydrosphingosine-based fusion inhibitors against wild-type and enfuvirtide-resistant HIV-1.
FASEB J. 2012.
17)  Yavlovich A, Singh A, Blumenthal R, Puri A.
A novel class of photo-triggerable liposomes containing DPPC:DC(8,9)PC as vehicles for delivery of doxorubcin to cells.
Biochim. Biophys. Acta. 1808: 117-26, 2011.
18)  Belanger JM, Raviv Y, Viard M, de la Cruz MJ, Nagashima K, Blumenthal R.
Effects of UVA irradiation, aryl azides, and reactive oxygen species on the orthogonal inactivation of the human immunodeficiency virus (HIV-1).
Virology. 447: 221-228, 2011.
19)  Smith B, Lyakhov I, Loomis K, Needle D, Baxa U, Yavlovich A, Capala J, Blumenthal R, Puri A.
Hyperthermia-triggered intracellular delivery of anticancer agent to HER2(+) cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2(+) affisomes).
J Control Release. 153: 187-194, 2011.
20)  Puri A, Blumenthal R.
Polymeric Lipid Assemblies as Novel Theranostic Tools.
Acc Chem Res. 44: 1071-9, 2011.
21)  Colantonio S, Simpson JT, Fisher RJ, Yavlovich A, Belanger JM, Puri A, Blumenthal R.
Quantitative Analysis of Phospholipids Using Nanostructured Laser Desorption Ionization Targets.
Lipids. 46: 469-477, 2011.
22)  Garg H, Viard M, Jacobs A, Blumenthal R.
Targeting HIV-1 gp41-induced Fusion and Pathogenesis for Anti-viral Therapy.
Curr Top Med Chem. 11: 2947-58, 2011.
23)  Ashkenazi A, Viard M, Wexler-Cohen Y, Blumenthal R, Shai Y.
Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41.
FASEB J. 25: 2156-2166, 2011.
24)  Belanger JM, Raviv Y, Viard M, Jason de la Cruz M, Nagashima K, Blumenthal R.
Characterization of the Effects of Aryl-azido Compounds and UVA Irradiation on the Viral Proteins and Infectivity of Human Immunodeficiency Virus Type 1.
Photochem. Photobiol. 86: 1099-108, 2010.
25)  Garg H, Salcedo R, Trinchieri G, Blumenthal R.
Improved nonviral cancer suicide gene therapy using survivin promoter-driven mutant Bax.
Cancer Gene Ther. 17: 155-63, 2010.
26)  Yavlovich A, Smith B, Gupta K, Blumenthal R, Puri A.
Light-sensitive lipid-based nanoparticles for drug delivery: design principles and future considerations for biological applications.
Mol. Membr. Biol. 27: 364-81, 2010.
27)  Rosa Borges A, Wieczorek L, Johnson B, Benesi AJ, Brown BK, Kensinger RD, Krebs FC, Wigdahl B, Blumenthal R, Puri A, McCutchan FE, Birx DL, Polonis VR, Schengrund CL.
Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1.
Virology. 408: 80-8, 2010.
28)  Loomis K, Smith B, Feng Y, Garg H, Yavlovich A, Campbell-Massa R, Dimitrov DS, Blumenthal R, Xiao X, Puri A.
Specific targeting to B cells by lipid-based nanoparticles conjugated with a novel CD22-ScFv.
Exp Mol Pathol. 88(2): 238-49, 2010.
29)  Wexler-Cohen Y, Ashkenazi A, Viard M, Blumenthal R, Shai Y.
Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain.
FASEB J. 24(11): 4196-202, 2010.
30)  Zielinski R, Lyakhov I, Jacobs A, Chertov O, Kramer-Marek G, Francella N, Stephen A, Fisher R, Blumenthal R, Capala J.
Affitoxin--a novel recombinant, HER2-specific, anticancer agent for targeted therapy of HER2-positive tumors.
J. Immunother. 32(8): 817-25, 2009.
31)  Garg H, Joshi A, Blumenthal R.
Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants.
AIDS Res. Hum. Retroviruses. 25: 811-7, 2009.
32)  Wang PC, Blumenthal RP, Zhao Y, Schneider JA, Miller N, Grodzinski P, Gottesman MM, Tinkle S, Wang K, Wang C, Liang XJ.
Building scientific progress without borders: nanobiology and nanomedicine in China and the U.S.
Cancer Res. 69: 5294-5, 2009.
33)  Kang J, Garg H, Sigano DM, Francella N, Blumenthal R, Marquez VE.
Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.
Bioorg. Med. Chem. 17(4): 1498-505, 2009.
34)  Yavlovich A, Singh A, Tarasov S, Capala J, Blumenthal R, Puri A.
Design of Liposomes Containing Photopolymerizable Phospholipids for Triggered Release of Contents.
J Therm Anal Calorim. 98: 97-104, 2009.
35)  Puri A, Blumenthal R.
HIV type 1 Entry Correlates with Plasma Membrane Microdomain Lateral Assemblies of Receptors: Implications in HIV/AIDS Treatment.
J Viral Entry. 3: 103-13, 2009.
36)  Puri A, Loomis K, Smith B, Lee J, Yavlovich A, Heldman E, Blumenthal R.
Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic.
Crit Rev Ther Drug Carrier Syst. 26(6): 523-80, 2009.
37)  Viard M, Garg H, Blumenthal R, Raviv Y.
Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death.
BMC Cell Biol. 10: 21, 2009.
38)  Jacobs A, Blumenthal R.
Understanding the Design Principles of Living Systems at the Nanoscale.
Curr Nanosci. 5: 45-50, 2009.
Full Text Article. [Journal]
39)  Thangapazham RL, Puri A, Tele S, Blumenthal R, Maheshwari RK.
Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells.
Int. J. Oncol. 32: 1119-23, 2008.
40)  Garg H, Francella N, Tony KA, Augustine LA, Barchi JJ, Fantini J, Puri A, Mootoo DR, Blumenthal R.
Glycoside analogs of beta-galactosylceramide, a novel class of small molecule antiviral agents that inhibit HIV-1 entry.
Antiviral Res. 80(1): 54-61, 2008.
41)  Puri A, Kramer-Marek G, Campbell-Massa R, Yavlovich A, Tele SC, Lee S, Clogston JD, Patri AK, Blumenthal R, Capala J.
HER2-specific affibody-conjugated thermosensitive liposomes (Affisomes) for improved delivery of anticancer agents.
J Liposome Res. 18: 293-307, 2008.
42)  Jacobs A, Garg H, Viard M, Raviv Y, Puri A, Blumenthal R.
HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: Implications for therapy and vaccine development.
Vaccine. 26(24): 3026-35, 2008.
43)  Viard M, Ablan SD, Zhou M, Veenstra TD, Freed EO, Raviv Y, Blumenthal R.
Photoinduced Reactivity of the HIV-1 Envelope Glycoprotein with a Membrane-Embedded Probe Reveals Insertion of Portions of the HIV-1 Gp41 Cytoplasmic Tail into the Viral Membrane.
Biochemistry. 47: 1977-1983, 2008.
44)  Rawat SS, Zimmerman C, Johnson BT, Cho E, Lockett SJ, Blumenthal R, Puri A.
Restricted lateral mobility of plasma membrane CD4 impairs HIV-1 envelope glycoprotein mediated fusion.
Mol. Membr. Biol. 25: 83-94, 2008.
45)  Garg H, Blumenthal R.
Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis.
Cell. Mol. Life Sci. 65(20): 3134-44, 2008.
46)  Jacobs A, Quraishi O, Huang X, Bousquet-Gagnon N, Nault G, Francella N, Alvord WG, Pham N, Soucy C, Robitaille M, Bridon D, Blumenthal R.
A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex.
J. Biol. Chem. 282: 32406-13, 2007.
47)  Sharma A, Raviv Y, Puri A, Viard M, Blumenthal R, Maheshwari RK.
Complete inactivation of Venezuelan equine encephalitis virus by 1,5-iodonaphthylazide.
Biochem. Biophys. Res. Commun. 358: 392-8, 2007.
48)  Warfield KL, Swenson DL, Olinger GG, Kalina WV, Viard M, Aitichou M, Chi X, Ibrahim S, Blumenthal R, Raviv Y, Bavari S, Aman MJ.
Ebola virus inactivation with preservation of antigenic and structural integrity by a photoinducible alkylating agent.
J. Infect. Dis. 196 Suppl 2: S276-83, 2007.
49)  Dimitrov AS, Jacobs A, Finnegan CM, Stiegler G, Katinger H, Blumenthal R.
Exposure of the Membrane-Proximal External Region of HIV-1 gp41 in the Course of HIV-1 Envelope Glycoprotein-Mediated Fusion.
Biochemistry. 46: 1398-401, 2007.
50)  Singh A, Lawson G, Shivakrupa R, Johnson B, Blumenthal R, Puri A.
Piroxicam Entrapped In Head-Group Polymerized Liposomes Inhibits Proliferation of IC2 Mast Cells In Vitro (Materials Research Symposium on Engineered Nanoscale Materials for the Diagnosis and Treatment of Diseases).
Volume 1019E. p. 1019-FF02-07. [Meeting Proceeding]
51)  Garg H, Joshi A, Freed EO, Blumenthal R.
Site-specific mutations in HIV-1 GP41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion.
J Biol Chem. 282: 16899-16906, 2007.
52)  Finnegan CM, Rawat SS, Cho EH, Guiffre DL, Lockett S, Merrill AH, Blumenthal R.
Sphingomyelinase Restricts the Lateral Diffusion of CD4 and Inhibits HIV Fusion.
J Virol. 81: 5294-5304, 2007.
53)  Blumenthal R, Dimitrov DS.
Targeting the Sticky Fingers of HIV-1.
Cell. 129: 243-5, 2007.
54)  Sidorov I, Blumenthal R, Dimitrov D.
A model of drug delivery to normal and cancer cells by antibody-targeted nanoliposomes.
J. Comp. & Theor. Nanosci. 3: 405-11, 2006.
55)  Lund N, Branch DR, Mylvaganam M, Chark D, Ma X, Sakac D, Binnington B, Fantini J, Puri A, Blumenthal R, Lingwood CA.
A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection.
AIDS. 20(3): 333-343, 2006.
56)  Finnegan C, Blumenthal R.
Dissecting HIV Fusion: Identifying Novel Targets for Entry Inhibitors.
Infect Disord Drug Targets. 6: 355-67, 2006.
57)  Garg H, Blumenthal R.
HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir.
J Leukoc Biol. 79(2): 351-62, 2006.
58)  Gallo SA, Reeves JD, Garg H, Foley B, Doms RW, Blumenthal R.
Kinetic studies of HIV-1 and HIV-2 Envelope Glycoprotein-Mediated Fusion.
Retrovirology. 3: 90, 2006.
59)  Garg H, Blumenthal R.
Mutational analysis of HIV-1 gp41 mediated apoptosis and its correlation with fusion/hemifusion.
Retrovirology. 3 Suppl 1: S89, 2006.
60)  Rawat SS, Viard M, Gallo SA, Blumenthal R, Puri A.
Sphingolipids, cholesterol, and HIV-1: A paradigm in viral fusion.
Glycoconj J. 23: 189-97, 2006.
61)  Wexler-Cohen Y, Johnson BT, Puri A, Blumenthal R, Shai Y.
Structurally altered peptides reveal an important role for N-terminal heptad repeat binding and stability in the inhibitory action of HIV-1 peptide, Dp178.
J Biol Chem. 281(14): 9005-10, 2006.
62)  Fox TE, Finnegan CM, Blumenthal R, Kester M.
The clinical potential of sphingolipid-based therapeutics.
Cell Mol Life Sci. 63(9): 1017-23, 2006.
63)  Ablan S, Rawat SS, Viard M, Wang JM, Puri A, Blumenthal R.
The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion.
Virol J. 3: 104, 2006.
64)  Gallo SA, Wang W, Rawat SS, Jung G, Waring AJ, Cole AM, Lu H, Yan X, Daly NL, Craik DJ, Jiang S, Lehrer RI, Blumenthal R.
Theta -Defensins prevent HIV-1 env-mediated fusion by binding gp41 and blocking 6-helix bundle formation.
J Biol Chem. 281: 18787-18792, 2006.
65)  Dimitrov AS, Louis JM, Bewley CA, Clore GM, Blumenthal R.
Conformational Changes in HIV-1 gp41 in the Course of HIV-1 Envelope Glycoprotein-Mediated Fusion and Inactivation.
Biochemistry. 44: 12471-12479, 2005.
66)  Finnegan CM, Blumenthal R.
Fenretinide inhibits HIV infection by promoting viral endocytosis.
Antiviral Res. 69(2): 116-23, 2005.
67)  Ray PE, Soler-Garci­a AA, Xu L, Soderland C, Blumenthal R, Puri A.
Fusion of HIV-1 envelope-expressing cells to human glomerular endothelial cells through an CXCR4-mediated mechanism.
Pediatr Nephrol. 20(10): 1401-9, 2005.
68)  Sun L, Finnegan CM, Kish-Catalone T, Blumenthal R, Garzino-Demo P, La Terra Maggiore GM, Berrone S, Kleinman C, Wu Z, Abdelwahab S, Lu W, Garzino-Demo A.
Human {beta}-Defensins Suppress Human Immunodeficiency Virus Infection: Potential Role in Mucosal Protection.
J Virol. 79: 14318-29, 2005.
69)  Raviv Y, Viard M, Bess JW, Chertova E, Blumenthal R.
Inactivation of retroviruses with preservation of structural integrity by targeting the hydrophobic domain of the viral envelope.
J Virol. 79: 12394-400, 2005.
70)  Wyss S, Dimitrov AS, Baribaud F, Edwards TG, Blumenthal R, Hoxie JA.
Regulation of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Fusion by a Membrane-Interactive Domain in the gp41 Cytoplasmic Tail.
J Virol. 79: 12231-41, 2005.
71)  Jaroniec CP, Kaufman JD, Stahl SJ, Viard M, Blumenthal R, Wingfield PT, Bax A.
Structure and Dynamics of Micelle-Associated Human Immunodeficiency Virus gp41 Fusion Domain(,).
Biochemistry. 44: 16167-16180, 2005.
72)  Puri A, Rawat SS, Lin HM, Finnegan CM, Mikovits J, Ruscetti FW, Blumenthal R.
An inhibitor of glycosphingolipid metabolism blocks HIV-1 infection of primary T-cells.
AIDS. 18: 849-58, 2004.
73)  Finnegan CM, Rawat SS, Puri A, Wang JM, Ruscetti FW, Blumenthal R.
Ceramide, a target for antiretroviral therapy.
Proc Natl Acad Sci U S A. 101: 15452-15457, 2004.
74)  Rawat SS, Gallo SA, Eaton J, Martin TD, Ablan S, KewalRamani VN, Wang JM, Blumenthal R, Puri A.
Elevated Expression of GM3 in Receptor-Bearing Targets Confers Resistance to Human Immunodeficiency Virus Type 1 Fusion.
J Virol. 78: 7360-8, 2004.
75)  Rawat SS, Eaton J, Gallo SA, Martin TD, Ablan S, Ratnayake S, Viard M, KewalRamani VN, Wang JM, Blumenthal R, Puri A.
Functional expression of CD4, CXCR4, and CCR5 in glycosphingolipid-deficient mouse melanoma GM95 cells and susceptibility to HIV-1 envelope glycoprotein-triggered membrane fusion.
Virology. 318: 55-65, 2004.
76)  Gerber D, Pritsker M, Gunther-Ausborn S, Johnson B, Blumenthal R, Shai Y.
Inhibition of HIV-1 envelope glycoprotein-mediated cell fusion by a D,L-amino acid-containing fusion peptide: Possible recognition of the fusion complex.
J Biol Chem. 2004.
77)  Gallo SA, Clore GM, Louis JM, Bewley CA, Blumenthal R.
Temperature-Dependent Intermediates in HIV-1 Envelope Glycoprotein-Mediated Fusion Revealed by Inhibitors that Target N- and C-Terminal Helical Regions of HIV-1 gp41.
Biochemistry. 43: 8230-3, 2004.
78)  Shnaper S, Sackett K, Gallo SA, Blumenthal R, Shai Y.
The C- and the N-terminal regions of gp41 ectodomain fuse membranes enriched and not enriched with cholesterol, respectively.
J Biol Chem. 279: 18526-34, 2004.
79)  Viard M, Parolini I, Rawat SS, Fecchi K, Sargiacomo M, Puri A, Blumenthal R.
The role of glycosphingolipids in HIV signaling, entry and pathogenesis.
Glycoconj J. 20: 213-22, 2004.
80)  Gallo SA, Sackett K, Rawat SS, Shai Y, Blumenthal R.
The Stability of the Intact Envelope Glycoproteins is a Major Determinant of Sensitivity of HIV/SIV to Peptidic Fusion Inhibitors.
J Mol Biol. 340: 9-14, 2004.
81)  Peisajovich SG, Gallo SA, Blumenthal R, Shai Y.
C-terminal octylation rescues an inactive T20 mutant: implications for the mechanism of HIV/SIV-induced membrane fusion.
J Biol Chem. 278: 21012-21017, 2003.
82)  Blumenthal R, Clague MJ, Durell SR, Epand RM.
Membrane fusion.
Chem Rev. 103: 53-69, 2003.
83)  Rawat SS, Viard M, Gallo SA, Rein A, Blumenthal R, Puri A.
Modulation of entry of enveloped viruses by cholesterol and sphingolipids (Review).
Mol Membr Biol. 20: 243-54, 2003.
84)  Lin X, Derdeyn CA, Blumenthal R, West J, Hunter E.
Progressive Truncations C Terminal to the Membrane-Spanning Domain of Simian Immunodeficiency Virus Env Reduce Fusogenicity and Increase Concentration Dependence of Env for Fusion.
J Virol. 77: 7067-7077, 2003.
85)  Dimitrov AS, Rawat SS, Jiang S, Blumenthal R.
Role of the Fusion Peptide and Membrane-Proximal Domain in HIV-1 Envelope Glycoprotein-Mediated Membrane Fusion.
Biochemistry. 42: 14150-14158, 2003.
86)  Gallo SA, Finnegan CM, Viard M, Raviv Y, Dimitrov A, Rawat SS, Puri A, Durell S, Blumenthal R.
The HIV Env-mediated fusion reaction.
Biochim Biophys Acta. 1614: 36-50, 2003.
87)  Remeta DP, Krumbiegel M, Minetti CA, Puri A, Ginsburg A, Blumenthal R.
Acid-induced changes in thermal stability and fusion activity of influenza hemagglutinin.
Biochemistry. 41: 2044-54, 2002.
88)  Blumenthal R, Gallo SA, Viard M, Raviv Y, Puri A.
Fluorescent lipid probes in the study of viral membrane fusion.
Chem Phys Lipids. 116: 39-55, 2002.
89)  Viard M, Blumenthal R, Raviv Y.
Improved separation of integral membrane proteins by continuous elution electrophoresis with simultaneous detergent exchange: application to the purification of the fusion protein of the human immunodeficiency virus type 1.
Electrophoresis. 23: 1659-66, 2002.
90)  Puri A, Paternostre M, Blumenthal R.
Lipids in viral fusion.
Methods Mol Biol. 199: 61-81, 2002.
91)  Raviv Y, Viard M, Bess J, Blumenthal R.
Quantitative measurement of fusion of HIV-1 and SIV with cultured cells using photosensitized labeling.
Virology. 293: 243-51, 2002.
92)  Viard M, Parolini I, Sargiacomo M, Fecchi K, Ramoni C, Ablan S, Ruscetti FW, Wang JM, Blumenthal R.
Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells.
J Virol. 76: 11584-95, 2002.
93)  Reeves JD, Gallo SA, Ahmad N, Miamidian JL, Harvey PE, Sharron M, Pohlmann S, Sfakianos JN, Derdeyn CA, Blumenthal R, Hunter E, Doms RW.
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics.
Proc Natl Acad Sci U S A. 99: 16249-54, 2002.
94)  Dimitrov AS, Xiao X, Dimitrov DS, Blumenthal R.
Early intermediates in HIV-1 envelope glycoprotein-mediated fusion triggered by CD4 and co-receptor complexes.
J Biol Chem. 276: 30335-41, 2001.
95)  Ablan S, Rawat SS, Blumenthal R, Puri A.
Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line.
Arch Virol. 146: 2227-38, 2001.
96)  Kliger Y, Gallo SA, Peisajovich SG, Munoz-Barroso I, Avkin S, Blumenthal R, Shai Y.
Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage.
J Biol Chem. 276: 1391-7, 2001.
97)  Korte T, Epand RF, Epand RM, Blumenthal R.
Role of the Glu residues of the influenza hemagglutinin fusion peptide in the pH dependence of fusion activity.
Virology. 289: 353-61, 2001.
98)  Hug P, Lin HM, Korte T, Xiao X, Dimitrov DS, Wang JM, Puri A, Blumenthal R.
Glycosphingolipids promote entry of a broad range of human immunodeficiency virus type 1 isolates into cell lines expressing CD4, CXCR4, and/or CCR5.
J Virol. 74: 6377-85, 2000.
99)  Puri A, Riley JL, Kim D, Ritchey DW, Hug P, Jernigan K, Rose P, Blumenthal R, Carroll RG.
Influenza virus upregulates CXCR4 expression in CD4+ cells.
AIDS Res Hum Retroviruses. 16: 19-25, 2000.
100)  Kliger Y, Peisajovich SG, Blumenthal R, Shai Y.
Membrane-induced conformational change during the activation of HIV-1 gp41.
J Mol Biol. 301: 905-14, 2000.
101)  Raviv Y, Puri A, Blumenthal R.
P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane.
FASEB J. 14: 511-5, 2000.
102)  Hoover DM, Rajashankar KR, Blumenthal R, Puri A, Oppenheim JJ, Chertov O, Lubkowski J.
The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
J Biol Chem. 275: 32911-8, 2000.
103)  Jernigan KM, Blumenthal R, Puri A.
Varying effects of temperature, Ca(2+) and cytochalasin on fusion activity mediated by human immunodeficiency virus type 1 and type 2 glycoproteins.
FEBS Lett. 474: 246-51, 2000.
104)  Korte T, Ludwig K, Booy FP, Blumenthal R, Herrmann A.
Conformational intermediates and fusion activity of influenza virus hemagglutinin.
J Virol. 73: 4567-74, 1999.
105)  Puri A, Hug P, Jernigan K, Rose P, Blumenthal R.
Role of glycosphingolipids in HIV-1 entry: requirement of globotriosylceramide (Gb3) in CD4/CXCR4-dependent fusion.
Biosci Rep. 19: 317-25, 1999.
106)  Muñoz-Barroso I, Salzwedel K, Hunter E, Blumenthal R.
Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion.
J Virol. 73: 6089-92, 1999.
107)  Blumenthal R, Morris SJ.
The influenza haemagglutinin-induced fusion cascade: effects of target membrane permeability changes.
Mol Membr Biol. 16: 43-7, 1999.
108)  Pritsker M, Jones P, Blumenthal R, Shai Y.
A synthetic all D-amino acid peptide corresponding to the N-terminal sequence of HIV-1 gp41 recognizes the wild-type fusion peptide in the membrane and inhibits HIV-1 envelope glycoprotein-mediated cell fusion.
Proc Natl Acad Sci U S A. 95: 7287-92, 1998.
109)  Jones PL, Korte T, Blumenthal R.
Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors.
J Biol Chem. 273: 404-9, 1998.
110)  Muñoz-Barroso I, Durell S, Sakaguchi K, Appella E, Blumenthal R.
Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41.
J Cell Biol. 140: 315-23, 1998.
111)  Puri A, Hug P, Muñoz-Barroso I, Blumenthal R.
Human erythrocyte glycolipids promote HIV-1 envelope glycoprotein-mediated fusion of CD4+ cells.
Biochem Biophys Res Commun. 242: 219-25, 1998.
112)  Howard OM, Korte T, Tarasova NI, Grimm M, Turpin JA, Rice WG, Michejda CJ, Blumenthal R, Oppenheim JJ.
Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor-mediated function.
J Leukoc Biol. 64: 6-13, 1998.
113)  Puri A, Hug P, Jernigan K, Barchi J, Kim HY, Hamilton J, Wiels J, Murray GJ, Brady RO, Blumenthal R.
The neutral glycosphingolipid globotriaosylceramide promotes fusion mediated by a CD4-dependent CXCR4-utilizing HIV type 1 envelope glycoprotein.
Proc Natl Acad Sci U S A. 95: 14435-40, 1998.
114)  Blumenthal R, Dimitrov DS.
Hoffman JF, Jamieson JC, eds.
Membrane Fusion. In: Handbook of Physiology: Cell Physiology.
New York: Oxford University Press; 1997. p. 563-603 [Book Chapter]
115)  Pak CC, Puri A, Blumenthal R.
Conformational changes and fusion activity of vesicular stomatitis virus glycoprotein: [125I]iodonaphthyl azide photolabeling studies in biological membranes.
Biochemistry. 36: 8890-6, 1997.
116)  Kliger Y, Aharoni A, Rapaport D, Jones P, Blumenthal R, Shai Y.
Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell Fusion. Structure-function study.
J Biol Chem. 272: 13496-505, 1997.
117)  Paternostre M, Viard M, Meyer O, Ghanam M, Ollivon M, Blumenthal R.
Solubilization and reconstitution of vesicular stomatitis virus envelope using octylglucoside.
Biophys J. 72: 1683-94, 1997.
118)  Durell SR, Martin I, Ruysschaert JM, Shai Y, Blumenthal R.
What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review).
Mol Membr Biol. 14: 97-112, 1997.
119)  Blumenthal R, Sarkar DP, Durell S, Howard DE, Morris SJ.
Dilation of the influenza hemagglutinin fusion pore revealed by the kinetics of individual cell-cell fusion events.
J Cell Biol. 135: 63-71, 1996.
120)  Pak CC, Blumenthal R.
Effect of X31 influenza virus fusion on phosphatidylserine asymmetry in erythrocytes.
Biochim Biophys Acta. 1278: 98-104, 1996.
121)  Puri A, Morris SJ, Jones P, Ryan M, Blumenthal R.
Heat-resistant factors in human erythrocyte membranes mediate CD4-dependent fusion with cells expressing HIV-1 envelope glycoproteins.
Virology. 219: 262-7, 1996.
122)  Lowy RJ, Sarkar DP, Whitnall MH, Blumenthal R.
Differences in dispersion of influenza virus lipids and proteins during fusion.
Exp Cell Res. 216: 411-21, 1995.
123)  Morris SJ, Howard DE, Cheng TH, Sarkar DP, Blumenthal R.
Hemagglutinin-catalyzed cell-cell fusion: Kinetics of initial pore formation from video rate, multi-wavelengh, fluorescence microscopy.
J. Microsc. Soc. 1: 59-66, 1995.
124)  Reda T, Blumenthal R, Müller P, Herrmann A.
Influence of the spectrin network on fusion of influenza virus with red blood cells.
Mol Membr Biol. 12: 271-6, 1995.
125)  Burkly L, Mulrey N, Blumenthal R, Dimitrov DS.
Synergistic inhibition of human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies.
J Virol. 69: 4267-73, 1995.
126)  Blumenthal R, Pak CC, Raviv Y, Krumbiegel M, Bergelson LD, Morris SJ, Lowy RJ.
Transient domains induced by influenza haemagglutinin during membrane fusion.
Mol Membr Biol. 12: 135-42, 1995.
127)  Blumenthal R, Pak CC, Krumbiegel M, Lowy HR, Puri A, Elson HF, Dimitrov DS.
Verna R, eds.
How viral envelope glycoproteins negotiate the entry of genetic material into the cell. In: The Challenge of Biotechnology: From Laboratory Diagnosis to Clinical Therapy.
Rome: Ares-Serono Symposia; 1994. p. 151-73 [Book Chapter]
128)  Elson HF, Dimitrov DS, Blumenthal R.
A trans-dominant mutation in human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp41 inhibits membrane fusion when expressed in target cells.
Mol Membr Biol. 11: 165-9, 1994.
129)  Pak CC, Krumbiegel M, Blumenthal R, Raviv Y.
Detection of influenza hemagglutinin interaction with biological membranes by photosensitized activation of [125I]iodonaphthylazide.
J Biol Chem. 269: 14614-9, 1994.
130)  Pak CC, Krumbiegel M, Blumenthal R.
Intermediates in influenza virus PR/8 haemagglutinin-induced membrane fusion.
J Gen Virol. 75 ( Pt 2): 395-9, 1994.
131)  Krumbiegel M, Herrmann A, Blumenthal R.
Kinetics of the low pH-induced conformational changes and fusogenic activity of influenza hemagglutinin.
Biophys J. 67: 2355-60, 1994.
132)  Dimitrov DS, Blumenthal R.
Photoinactivation and kinetics of membrane fusion mediated by the human immunodeficiency virus type 1 envelope glycoprotein.
J Virol. 68: 1956-61, 1994.
133)  Zimmerberg J, Blumenthal R, Sarkar DP, Curran M, Morris SJ.
Restricted movement of lipid and aqueous dyes through pores formed by influenza hemagglutinin during cell fusion.
J Cell Biol. 127: 1885-94, 1994.
134)  Golding H, Manischewitz J, Vujcic L, Blumenthal R, Dimitrov DS.
The phorbol ester phorbol myristate acetate inhibits human immunodeficiency virus type 1 envelope-mediated fusion by modulating an accessory component(s) in CD4-expressing cells.
J Virol. 68: 1962-9, 1994.
135)  Clague MJ, Schoch C, Blumenthal R.
Bentz J, eds.
Towards a dissection of the influenza hemagglutinin mediated membrane fusion pathway. In: Viral Fusion Mechanisms.
Boca Raton: CRC Press; 1993. p. 113-32 [Book Chapter]
136)  Puri A, Krumbiegel M, Dimitrov D, Blumenthal R.
A new approach to measure fusion activity of cloned viral envelope proteins: fluorescence dequenching of octadecylrhodamine-labeled plasma membrane vesicles fusing with cells expressing vesicular stomatitis virus glycoprotein.
Virology. 195: 855-8, 1993.
137)  Dimitrov DS, Broder CC, Berger EA, Blumenthal R.
Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction.
J Virol. 67: 1647-52, 1993.
138)  Golding H, Blumenthal R, Manischewitz J, Littman DR, Dimitrov DS.
Cell fusion mediated by interaction of a hybrid CD4.CD8 molecule with the human immunodeficiency virus type 1 envelope glycoprotein does occur after a long lag time.
J Virol. 67: 6469-75, 1993.
139)  Herrmann A, Clague MJ, Blumenthal R.
Enhancement of viral fusion by nonadsorbing polymers.
Biophys J. 65: 528-34, 1993.
140)  Golding H, Dimitrov DS, Blackburn R, Manischewitz J, Blumenthal R, Golding B.
Fusion of human B cell lines with HIV-1 envelope-expressing T cells is enhanced by antigen-specific Ig receptors. Possible mechanism for elimination of gp120-specific B cells in vivo.
J Immunol. 150: 2506-16, 1993.
141)  Bagai S, Puri A, Blumenthal R, Sarkar DP.
Hemagglutinin-neuraminidase enhances F protein-mediated membrane fusion of reconstituted Sendai virus envelopes with cells.
J Virol. 67: 3312-8, 1993.
142)  Morris SJ, Zimmerberg J, Sarkar DP, Blumenthal R.
Kinetics of cell fusion mediated by viral spike glycoproteins.
Methods Enzymol. 221: 42-58, 1993.
143)  Puri A, Clague MJ, Schoch C, Blumenthal R.
Kinetics of fusion of enveloped viruses with cells.
Methods Enzymol. 220: 277-87, 1993.
144)  Dimitrov DS, Franzoso G, Salman M, Blumenthal R, Tarshis M, Barile MF, Rottem S.
Mycoplasma fermentans (incognitus strain) cells are able to fuse with T lymphocytes.
Clin Infect Dis. 17 Suppl 1: S305-8, 1993.
145)  Dimitrov DS, Willey RL, Sato H, Chang LJ, Blumenthal R, Martin MA.
Quantitation of human immunodeficiency virus type 1 infection kinetics.
J Virol. 67: 2182-90, 1993.
146)  Herrmann A, Clague MJ, Blumenthal R.
Role of target membrane structure in fusion with influenza virus: effect of modulating erythrocyte transbilayer phospholipid distribution.
Membr Biochem. 10: 3-15, 1993.
147)  Schoch C, Blumenthal R.
Role of the fusion peptide sequence in initial stages of influenza hemagglutinin-induced cell fusion.
J Biol Chem. 268: 9267-74, 1993.
148)  Broder CC, Dimitrov DS, Blumenthal R, Berger EA.
The block to HIV-1 envelope glycoprotein-mediated membrane fusion in animal cells expressing human CD4 can be overcome by a human cell component(s).
Virology. 193: 483-91, 1993.
149)  Walter A, Lesieur S, Blumenthal R, Ollivon M.
Gregoriadid G, eds.
Size characterization of liposomes by HPLC. In: Liposome Technology, 2nd Edition.
Boca Raton: CRC Press; 1992. p. 271-90 [Book Chapter]
150)  Schoch C, Blumenthal R, Clague MJ.
A long-lived state for influenza virus-erythrocyte complexes committed to fusion at neutral pH.
FEBS Lett. 311: 221-5, 1992.
151)  Guy HR, Durell SR, Schoch C, Blumenthal R.
Analyzing the fusion process of influenza hemagglutinin by mutagenesis and molecular modeling.
Biophys J. 62: 95-7, 1992.
152)  Dimitrov DS, Hillman K, Manischewitz J, Blumenthal R, Golding H.
Correlation between kinetics of soluble CD4 interactions with HIV-1-Env-expressing cells and inhibition of syncytia formation: implications for mechanisms of cell fusion and therapy for AIDS.
AIDS. 6: 249-56, 1992.
153)  Krumbiegel M, Dimitrov DS, Puri A, Blumenthal R.
Dextran sulfate inhibits fusion of influenza virus and cells expressing influenza hemagglutinin with red blood cells.
Biochim Biophys Acta. 1110: 158-64, 1992.
154)  Franzoso G, Dimitrov DS, Blumenthal R, Barile MF, Rottem S.
Fusion of Mycoplasma fermentans strain incognitus with T-lymphocytes.
FEBS Lett. 303: 251-4, 1992.
155)  Puri A, Dimitrov DS, Golding H, Blumenthal R.
Interactions of CD4+ plasma membrane vesicles with HIV-1 and HIV-1 envelope glycoprotein-expressing cells.
J Acquir Immune Defic Syndr. 5: 915-20, 1992.
156)  Dimitrov DS, Willey RL, Martin MA, Blumenthal R.
Kinetics of HIV-1 interactions with sCD4 and CD4+ cells: implications for inhibition of virus infection and initial steps of virus entry into cells.
Virology. 187: 398-406, 1992.
157)  Dimitrov DS, Hillman K, Manischewitz J, Blumenthal R, Golding H.
Kinetics of soluble CD4 binding to cells expressing human immunodeficiency virus type 1 envelope glycoprotein.
J Virol. 66: 132-8, 1992.
158)  Golding H, Dimitrov DS, Blumenthal R.
LFA-1 adhesion molecules are not involved in the early stages of HIV-1 env-mediated cell membrane fusion.
AIDS Res Hum Retroviruses. 8: 1593-8, 1992.
159)  Puri A, Grimaldi S, Blumenthal R.
Role of viral envelope sialic acid in membrane fusion mediated by the vesicular stomatitis virus envelope glycoprotein.
Biochemistry. 31: 10108-13, 1992.
160)  Blumenthal R, Puri A, Dimitrov DS.
Verna R, Nishizuka Y, eds.
Initial steps of enveloped virus entry into animal cells. In: Biotechnology of Cell Regulation.
New York: Raven Press; 1991. p. 115-33 [Book Chapter]
161)  Herrmann A, Zachowski A, Devaux PF, Blumenthal R.
Ohki S, eds.
Control of fusion of biological membranes by phospholipid asymmetry. In: Cell and Model Membrane Interactions.
New York: Plenum; 1991. p. 113-8 [Book Chapter]
162)  Dimitrov DS, Blumenthal R.
Ohki S, eds.
Kinetics of intermembrane interactions leading to fusion. In: Cell and Model Membrane Interactions.
New York: Plenum; 1991. p. 229-47 [Book Chapter]
163)  Blumenthal R, Schoch C, Puri A, Clague MJ.
A dissection of steps leading to viral envelope protein-mediated membrane fusion.
Ann N Y Acad Sci. 635: 285-96, 1991.
164)  Clague MJ, Schoch C, Blumenthal R.
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface density.
J Virol. 65: 2402-7, 1991.
165)  Dimitrov DS, Golding H, Blumenthal R.
Initial stages of HIV-1 envelope glycoprotein-mediated cell fusion monitored by a new assay based on redistribution of fluorescent dyes.
AIDS Res Hum Retroviruses. 7: 799-805, 1991.
166)  Clague MJ, Knutson JR, Blumenthal R, Herrmann A.
Interaction of influenza hemagglutinin amino-terminal peptide with phospholipid vesicles: a fluorescence study.
Biochemistry. 30: 5491-7, 1991.
167)  Blumenthal R, Loyter A.
Reconstituted viral envelopes--'Trojan horses' for drug delivery and gene therapy.
Trends Biotechnol. 9: 41-5, 1991.
168)  Kaplan D, Zimmerberg J, Puri A, Sarkar DP, Blumenthal R.
Single cell fusion events induced by influenza hemagglutinin: studies with rapid-flow, quantitative fluorescence microscopy.
Exp Cell Res. 195: 137-44, 1991.
169)  Cao CJ, Lockwich T, Scott TL, Blumenthal R, Shamoo AE.
Uncoupling of Ca2+ transport from ATP hydrolysis activity of sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPase.
Mol Cell Biochem. 103: 97-111, 1991.
170)  Walter A, Eidelman O, Ollivon M, Blumenthal R.
Wilschut J, Hoekstra D, eds.
Functional reconstitution of viral envelopes. In: Cellular Membrane Fusion: Fundamental Mechanisms and Applications of Membrane Fusion Techniques.
New York: Marcel Dekker; 1990. p. 395-418 [Book Chapter]
171)  Puri A, Booy FP, Doms RW, White JM, Blumenthal R.
Conformational changes and fusion activity of influenza virus hemagglutinin of the H2 and H3 subtypes: effects of acid pretreatment.
J Virol. 64: 3824-32, 1990.
172)  Herrmann A, Clague MJ, Puri A, Morris SJ, Blumenthal R, Grimaldi S.
Effect of erythrocyte transbilayer phospholipid distribution on fusion with vesicular stomatitis virus.
Biochemistry. 29: 4054-8, 1990.
173)  Doms RW, Blumenthal R, Moss B.
Fusion of intra- and extracellular forms of vaccinia virus with the cell membrane.
J Virol. 64: 4884-92, 1990.
174)  Clague MJ, Schoch C, Zech L, Blumenthal R.
Gating kinetics of pH-activated membrane fusion of vesicular stomatitis virus with cells: stopped-flow measurements by dequenching of octadecylrhodamine fluorescence.
Biochemistry. 29: 1303-8, 1990.
175)  Lowy RJ, Sarkar DP, Chen Y, Blumenthal R.
Observation of single influenza virus-cell fusion and measurement by fluorescence video microscopy.
Proc Natl Acad Sci U S A. 87: 1850-4, 1990.
176)  Harris HW, Hendler JS, Blumenthal R.
Toad urinary bladder vesicles containing particle aggregates possess very high water premeability.
Am. J. Physiol. 258: F237-43, 1990.
177)  Sarkar DP, Morris SJ, Eidelman O, Zimmerberg J, Blumenthal R.
Initial stages of influenza hemagglutinin-induced cell fusion monitored simultaneously by two fluorescent events: cytoplasmic continuity and lipid mixing.
J Cell Biol. 109: 113-22, 1989.
178)  Morris SJ, Sarkar DP, White JM, Blumenthal R.
Kinetics of pH-dependent fusion between 3T3 fibroblasts expressing influenza hemagglutinin and red blood cells. Measurement by dequenching of fluorescence.
J Biol Chem. 264: 3972-8, 1989.
179)  Blumenthal R, Puri A, Sarkar DP, Chen Y, Eidelman O, Morris SJ.
Membrane fusion mediated by viral spike glycoproteins (UCLA (Univ. Cal., Los. Angel.) Symp. Mol. Cell. Biol. New Ser).
Volume 90. p. 197-217. [Meeting Proceeding]
180)  Chen YD, Blumenthal R.
On the use of self-quenching fluorophores in the study of membrane fusion kinetics. The effect of slow probe redistribution.
Biophys Chem. 34: 283-92, 1989.
181)  Paternostre MT, Lowy RJ, Blumenthal R.
pH-dependent fusion of reconstituted vesicular stomatitis virus envelopes with Vero cells. Measurement by dequenching of fluorescence.
FEBS Lett. 243: 251-8, 1989.
182)  Blumenthal R, Puri A, Walter A, Eidelman O.
Ohki S, Doyle D, Flanagan T, Hui SW, Mayhew E, eds.
pH-dependent fusion of vesicular stomatitis virus with cells: Studies of mechanism based on an allosteric model. In: Molecular Mechanisms of Membrane Fusion.
New York: Plenum; 1988. p. 367-83 [Book Chapter]
183)  Morris SJ, Bradley D, Gibson GC, Smith PD, Blumenthal R.
Loew L, eds.
Use of membrane-associated fluorescence probes to monitor fusion of vesicles: Rapid kinetics of aggregation and fusion using pyrene excimer/monomer fluorescence. In: Spectroscopic Membrane Probes. Volume 1.
Boca Raton: CRC Press; 1988. p. 161-91 [Book Chapter]
184)  Puri A, Winick J, Lowy RJ, Covell D, Eidelman O, Walter A, Blumenthal R.
Activation of vesicular stomatitis virus fusion with cells by pretreatment at low pH.
J Biol Chem. 263: 4749-53, 1988.
185)  Eidelman O, Blumenthal R, Walter A.
Composition of octyl glucoside-phosphatidylcholine mixed micelles.
Biochemistry. 27: 2839-46, 1988.
186)  Blumenthal R.
Cooperativity in viral fusion.
Cell Biophys. 12: 1-12, 1988.
187)  Chejanovsky N, Nussbaum O, Loyter A, Blumenthal R.
Fusion of enveloped viruses with biological membranes. Fluorescence dequenching studies.
Subcell Biochem. 13: 415-56, 1988.
188)  Blumenthal R.
Membrane fusion mediated by viral spike glycoproteins: A model based on cooperativity and conformational changes.
Studia Biophysica. 127: 147-54, 1988.
189)  Ollivon M, Eidelman O, Blumenthal R, Walter A.
Micelle-vesicle transition of egg phosphatidylcholine and octyl glucoside.
Biochemistry. 27: 1695-703, 1988.
190)  Loyter A, Citovsky V, Blumenthal R.
The use of fluorescence dequenching measurements to follow viral membrane fusion events.
Methods Biochem Anal. 33: 129-64, 1988.
191)  Blumenthal R.
Membrane fusion.
Curr. Top. Membr. Transp. 29: 203-54, 1987.
192)  Blumenthal R, Bali-Puri A, Walter A, Covell D, Eidelman O.
pH-dependent fusion of vesicular stomatitis virus with Vero cells. Measurement by dequenching of octadecyl rhodamine fluorescence.
J Biol Chem. 262: 13614-9, 1987.
193)  Sarkar DP, Blumenthal R.
The role of the target membrane structure in fusion with Sendai virus.
Membr Biochem. 7: 231-47, 1987.
194)  Walter A, Margolis D, Mohan R, Blumenthal R.
Apocytochrome c induces pH-dependent vesicle fusion.
Membr Biochem. 6: 217-37, 1986.
195)  Weinstein JN, Blumenthal R, Klausner RD.
Carboxyfluorescein leakage assay for lipoprotein-liposome interaction.
Methods Enzymol. 128: 657-68, 1986.
196)  Blumenthal R, Seth P, Willingham MC, Pastan I.
pH-dependent lysis of liposomes by adenovirus.
Biochemistry. 25: 2231-7, 1986.
197)  Walter A, Steer CJ, Blumenthal R.
Polylysine induces pH-dependent fusion of acidic phospholipid vesicles: a model for polycation-induced fusion.
Biochim Biophys Acta. 861: 319-30, 1986.
198)  Ollivon M, Walter A, Blumenthal R.
Sizing and separation of liposomes, biological vesicles, and viruses by high-performance liquid chromatography.
Anal Biochem. 152: 262-74, 1986.
199)  Levin IW, Vincent JS, Blumenthal R, Steer CJ.
Use of vibrational spectroscopy in defining the role of clathrin in coated vesicle formation.
Biophys J. 49: 111-13, 1986.
200)  Citovsky V, Blumenthal R, Loyter A.
Fusion of Sendai virions with phosphatidylcholine-cholesterol liposomes reflects the viral activity required for fusion with biological membranes.
FEBS Lett. 193: 135-40, 1985.
201)  Spiegel S, Blumenthal R, Fishman PH, Handler JS.
Gangliosides do not move from apical to basolateral plasma membrane in cultured epithelial cells.
Biochim Biophys Acta. 821: 310-8, 1985.
202)  Morris SJ, Gibson CC, Smith PD, Greif PC, Stirk CW, Bradley D, Haynes DH, Blumenthal R.
Rapid kinetics of Ca2+-induced fusion of phosphatidylserine/phosphatidylethanolamine vesicles. The effect of bilayer curvature on leakage.
J Biol Chem. 260: 4122-7, 1985.
203)  Klausner RD, Blumenthal R, Innerarity T, Weinstein JN.
The interaction of apolipoprotein A-I with small unilamellar vesicles of L-alpha-dipalmitoylphosphatidylcholine.
J Biol Chem. 260: 13719-27, 1985.
204)  Henkart P, Henkart M, Millard P, Frederikse P, Bluestone J, Blumenthal R, Yue C, Reynolds C.
The role of cytoplasmic granules in cytotoxicity by large granular lymphocytes and cytotoxic T lymphocytes.
Adv Exp Med Biol. 184: 121-38, 1985.
205)  Morris SJ, Bradley D, Blumenthal R.
The use of cobalt ions as a collisional quencher to probe surface charge and stability of fluorescently labeled bilayer vesicles.
Biochim Biophys Acta. 818: 365-72, 1985.
206)  Weinstein JN, Ralston E, Leserman LD, Klausner RD, Dragsten P, Henkart P, Blumenthal R.
Gregoriadis G, eds.
Self-quenching of carboxyfluorescein: Fluorescence: Uses in studying liposome stability and liposome-cell interaction. In: Liposome Technology.
Boca Raton: CRC Press; 1984. p. 183-204 [Book Chapter]
207)  Blumenthal R, Kempf C, Renswoude JV, Weinstein JN, Klausner RD.
Oxender DL, eds.
Voltage-dependent orientation of membrane proteins. In: Protein Transport and Secretion.
New York: Alan R. Liss; 1984. p. 1-13 [Book Chapter]
208)  Klausner RD, van Renswoude J, Blumenthal R, Rivnay B.
Venter JC, Harrison LC, eds.
Reconstitution of membrane receptors. In: Receptor Biochemistry and Methodology. Volume 3, Molecular and Chemical Characterization of Membrane Receptors.
New York: Alan Liss; 1984. p. 209-39 [Book Chapter]
209)  Steer CJ, Bisher M, Blumenthal R, Steven AC.
Detection of membrane cholesterol by filipin in isolated rat liver coated vesicles is dependent upon removal of the clathrin coat.
J Cell Biol. 99: 315-9, 1984.
210)  Blumenthal R, Millard PJ, Henkart MP, Reynolds CW, Henkart PA.
Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors.
Proc Natl Acad Sci U S A. 81: 5551-5, 1984.
211)  Blumenthal R, Habig WH.
Mechanism of tetanolysin-induced membrane damage: studies with black lipid membranes.
J Bacteriol. 157: 321-3, 1984.
212)  Eidelman O, Schlegel R, Tralka TS, Blumenthal R.
pH-dependent fusion induced by vesicular stomatitis virus glycoprotein reconstituted into phospholipid vesicles.
J Biol Chem. 259: 4622-8, 1984.
213)  Blumenthal R, Henkart M, Steer CJ.
Clathrin-induced pH-dependent fusion of phosphatidylcholine vesicles.
J Biol Chem. 258: 3409-15, 1983.
214)  Sutcliffe J, Blumenthal R, Walter A, Foulds J.
Escherichia coli outer membrane protein K is a porin.
J Bacteriol. 156: 867-72, 1983.
215)  Katz Y, Hoffman ME, Blumenthal R.
Parametric analysis of membrane characteristics and membrane structure.
J. Theor. Biol. 105: 493-510, 1983.
216)  Klausner RD, Kempf C, Weinstein JN, Blumenthal R, Van Renswoude J.
The folding of ovalbumin. Renaturation in vitro versus biosynthesis in vitro.
Biochem J. 212: 801-10, 1983.
217)  Kempf C, Klausner RD, Blumenthal R, van Renswoude J.
Transport of proteins from the sites of genetic expression to their sites of functional expression: protein conformation and thermodynamic aspects.
Horiz Biochem Biophys. 7: 155-70, 1983.
218)  Blumenthal R, Kempf C, Van Renswoude J, Weinstein JN, Klausner RD.
Voltage-dependent orientation of membrane proteins.
J Cell Biochem. 22: 55-67, 1983.
219)  Dragsten PR, Handler JS, Blumenthal R.
Bolis S, Hoffman JF, Giebisch G, eds.
Asymmetry in epithelial cells: Is the tight junction a barrier to lateral diffusion in the plasma membrane?. In: Membranes in Growth and Development.
New York: Alan R. Liss; 1982. p. 525-36 [Book Chapter]
220)  Weinstein JN, Leserman LD, Henkart PA, Blumenthal R.
Senior J, Trouet A, eds.
Antibody- mediated targeting of liposomes. In: Targeting of Drugs.
New York: Plenum; 1982. p. 185-202 [Book Chapter]
221)  Kumar N, Blumenthal R, Henkart M, Weinstein JN, Klausner RD.
Aggregation and calcium-induced fusion of phosphatidylcholine vesicle-tubulin complexes.
J Biol Chem. 257: 15137-44, 1982.
222)  Dragsten PR, Handler JS, Blumenthal R.
Asymmetry in epithelial cells: is the tight junction a barrier to lateral diffusion in the plasma membrane.
Prog Clin Biol Res. 91: 525-36, 1982.
223)  Weinstein JN, Blumenthal R, van Renswoude J, Kempf C, Klausner RD.
Charge clusters and the orientation of membrane proteins.
J Membr Biol. 66: 203-12, 1982.
224)  Klausner RD, Berman M, Blumenthal R, Weinstein JN, Caplan SR.
Compartmental analysis of light-induced proton movement in reconstituted bacteriorhodopsin vesicles.
Biochemistry. 21: 3643-50, 1982.
225)  Dragsten PR, Handler JS, Blumenthal R.
Fluorescent membrane probes and the mechanism of maintenance of cellular asymmetry in epithelia.
Fed Proc. 41: 48-53, 1982.
226)  Steer CJ, Klausner RD, Blumenthal R.
Interaction of liver clathrin coat protein with lipid model membranes.
J Biol Chem. 257: 8533-40, 1982.
227)  Blumenthal R, Ralston E, Dragsten P, Leserman LD, Weinstein JN.
Lipid vesicle-cell interactions: analysis of a model for transfer of contents from adsorbed vesicles to cells.
Membr Biochem. 4: 283-303, 1982.
228)  Blumenthal R, Klausner RD.
The intreraction of membrane proteins with black lipid membranes.
Cell Surface Reviews. 8: 43-82, 1982.
229)  Blumenthal RP, Klausner RD, Weinstein JN.
Voltage-dependent changes of a membrane protein in lipid model membranes: Studies with the hepatic asialoglycoprotein receptor.
Biophys. J. 37: 122-24, 1982.
230)  Kempf C, Klausner RD, Weinstein JN, Van Renswoude J, Pincus M, Blumenthal R.
Voltage-dependent trans-bilayer orientation of melittin.
J Biol Chem. 257: 2469-76, 1982.
231)  Blumenthal R.
Colombetti LG, eds.
Transport mechanisms for radiotracers. In: Advances in Radiopharmacology.
Chicago: Univ. of Chicago Press; 1981. p. 150-6 [Book Chapter]
232)  Ralston E, Hjelmeland LM, Klausner RD, Weinstein JN, Blumenthal R.
Carboxyfluorescein as a probe for liposome-cell interactions: Effect of impurities and purification of the dye.
Biochim. Biophys. Acta. 649: 133-37, 1981.
233)  Klausner RD, Kumar N, Weinstein JN, Blumenthal R, Flavin M.
Interaction of tubulin with phospholipid vesicles. I. Association with vesicles at the phase transition.
J Biol Chem. 256: 5879-85, 1981.
234)  Kumar N, Klausner RD, Weinstein JN, Blumenthal R, Flavin M.
Interaction of tubulin with phospholipid vesicles. II. Physical changes of the protein.
J Biol Chem. 256: 5886-9, 1981.
235)  Dragsten PR, Blumenthal R, Handler JS.
Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane.
Nature. 294: 718-22, 1981.
236)  Weinstein JN, Klausner RD, Innerarity T, Ralston E, Blumenthal R.
Phase transition release, a new approach to the interaction of proteins with lipid vesicles. Application to lipoproteins.
Biochim Biophys Acta. 647: 270-84, 1981.
237)  Ralston E, Blumenthal R, Weinstein JN, Sharrow SO, Henkart P.
Lysophosphatidylcholine in liposomal membranes: enhanced permeability but little effect on transfer of a water-soluble fluorescent marker into human lymphocytes.
Biochim Biophys Acta. 597: 543-51, 1980.
238)  Leserman LD, Weinstein JN, Blumenthal R, Terry WD.
Receptor-mediated endocytosis of antibody-opsonized liposomes by tumor cells.
Proc Natl Acad Sci U S A. 77: 4089-93, 1980.
239)  Klausner RD, Bridges K, Tsunoo H, Blumenthal R, Weinstein JN, Ashwell G.
Reconstitution of the hepatic asialoglycoprotein receptor with phospholipid vesicles.
Proc Natl Acad Sci U S A. 77: 5087-91, 1980.
240)  Van Renswoude AJ, Blumenthal R, Weinstein JN.
Thin-layer chromatography with agarose gels. A quick, simple method for evaluating liposome size.
Biochim Biophys Acta. 595: 151-6, 1980.
241)  Blumenthal R, Klausner RD, Weinstein JN, Bridges K, Tsunoo H, Ashwell G.
Voltage-dependent translocation of hepatic binding protein.
Ann N Y Acad Sci. 358: 368-9, 1980.
242)  Blumenthal R, Klausner RD, Weinstein JN.
Voltage-dependent translocation of the asialoglycoprotein receptor across lipid membranes.
Nature. 288: 333-8, 1980.
243)  DeLisi C, Blumenthal R, eds.
Physical Chemical Aspects of Cell Surface Events in Cellular Regulation.
New York: Elsevier/North-Holland; 1979. [Book (Editor)]
244)  Blumenthal R, Shamoo AE.
O'Brien RD, eds.
Incorporation of transport molecules into black lipid membranes. In: The Receptors: A Comprehensive Treatise.
New York: Plenum; 1979. p. 215-45 [Book Chapter]
245)  Leserman LD, Weinstein JN, Blumenthal R, Sharrow SO, Terry WD.
Binding of antigen-bearing fluorescent liposomes to the murine myeloma tumor MOPC 315.
J Immunol. 122: 585-91, 1979.
246)  Dragsten P, Henkart P, Blumenthal R, Weinstein J, Schlessinger J.
Lateral diffusion of surface immunoglobulin, Thy-1 antigen, and a lipid probe in lymphocyte plasma membranes.
Proc Natl Acad Sci U S A. 76: 5163-7, 1979.
247)  Weinstein JN, Blumenthal R, Sharrow SO, Henkart PA.
Antibody-mediated targeting of liposomes: Binding to lymphocytes without incorporation of vesicle contents into cells.
Biochim. Biophys. Acta. 509: 272-88, 1978.
248)  Yatvin MB, Weinstein JN, Dennis WH, Blumenthal R.
Design of liposomes for enhanced local release of drugs by hyperthermia.
Science. 202: 1290-93, 1978.
249)  Kafka MS, Blumenthal R, Walker GA, Pollard HB.
The effect of Dopamine-B-hydroxylase on the electrical conductance of bimolecular lipid membranes.
Membr. Biochem. 1: 279-95, 1978.
250)  Yatvin MB, Weinstein JN, Dennis WH, Blumenthal R.
Use of hyperthermia to promote selective local release of drugs from liposomes (Conference on Clinical Prospects for Hypoxic Cell Sensitizers and Hyperthermia).
. p. 105-12. [Meeting Proceeding]
251)  Wolf DE, Schlessinger J, Elson EL, Webb WW, Blumenthal R, Henkart P.
Diffusion and patching of macromolecules on planar lipid bilayer membranes.
Biochemistry. 16: 3476-83, 1977.
252)  Rosenstreich DL, Blumenthal R.
Ionophorous activity and murine B lymphocyte mitogens.
J Immunol. 118: 129-36, 1977.
253)  Blumenthal R, Weinstein JN, Henkart P.
Lipid model membrane studies on immune cytotoxic mechanisms.
Adv Exp Med Biol. 84: 495-507, 1977.
254)  Blumenthal R, Weinstein JN, Henkart P.
Lipid model membrane studies on immune cytotoxic mechanisms (9th Rochester International Conference on Environmental Toxicity-Membrane Toxicity).
Miller MW, Shamoo AE, eds.
. p. 495-507. [Meeting Proceeding]
255)  Blumenthal R, Weinstein JN, Sharrow SO, Henkart P.
Liposome--lymphocyte interaction: saturable sites for transfer and intracellular release of liposome contents.
Proc Natl Acad Sci U S A. 74: 5603-7, 1977.
256)  Weinstein JN, Yoshikami S, Henkart P, Blumenthal R, Hagins WA.
Liposome-cell interaction: transfer and intracellular release of a trapped fluorescent marker.
Science. 195: 489-92, 1977.
257)  Blumenthal R.
Pattern formation in a model for cooperative membrane carrier transport.
Adv Biol Med Phys. 16: 165-76, 1977.
258)  Blumenthal R.
Schmitt FO, Schneider DM, Crothers DM, eds.
Thermodynamic and kinetic analysis of functional linkage in transmembrane transport. In: Functional Linkage in Biomolecular Systems.
New York: Raven Press; 1975. p. 149-62 [Book Chapter]
259)  Blumenthal R.
Instabilities, oscillations and chemical waves in an oligomeric model for membrane transport.
J Theor Biol. 49: 219-39, 1975.
260)  Henkart P, Blumenthal R.
Interaction of lymphocytes with lipid bilayer membranes: a model for lymphocyte-mediated lysis of target cells.
Proc Natl Acad Sci U S A. 72: 2789-93, 1975.
261)  Blumenthal R.
The interaction of hemocyanin and lymphocytes with lipid bilayer membranes.
Ann N Y Acad Sci. 264: 476-82, 1975.
262)  Blumenthal R.
The lipid bilayer membrane as an assay for ion-conductance-inducing materials isolated from biological membranes.
Ann N Y Acad Sci. 264: 483-5, 1975.
263)  Katchalsky A, Rowland V, Blumenthal R.
Dynamic patterns of brain cell assemblies.
Neurosci Res Program Bull. 12: 1-112, 1974.
264)  Blumenthal R.
Dynamic patterns of brain cell assemblies. 3. Continuity-discontinuity problems. Discontinuous systems.
Neurosci Res Program Bull. 12: 65-77, 1974.
265)  Shamoo AE, Myers MM, Blumenthal R, Albers RW.
Ionophoric material derived from eel membrane preparation. I. Chemical characteristics.
J Membr Biol. 19: 129-40, 1974.
266)  Blumenthal R, Shamoo AE.
Ionophoric material derived from eel membrane preparations. II. Electrical characteristics.
J Membr Biol. 19: 141-62, 1974.
267)  Ehrenstein G, Blumenthal R, Latorre R, Lecar H.
Kinetics of the opening and closing of individual excitability-inducing material channels in a lipid bilayer.
J Gen Physiol. 63: 707-21, 1974.
268)  Blumenthal R.
Dynamic patterns in active transport.
Israel J. Chem. 11: 341, 1973.
269)  Changeux JP, Podeleski T, Kasai M, Blumenthal R.
Anderson P, Jensen J, eds.
Some molecular aspects of membrane excitation studied with the eel electroplax. In: Excitatory Synaptic Mechanisms.
Oslo: University Press; 1970. p. 123-36 [Book Chapter]
270)  Blumenthal R, Changeux JP, Lefever R.
[A theory of electric excitation of biological membranes.
C R Acad Sci Hebd Seances Acad Sci D. 270: 389-92, 1970.
271)  Blumenthal R, Changeux JP.
About the changes of internal ionic concentration in the isolated electroplax during chemical excitation.
Biochim Biophys Acta. 219: 398-404, 1970.
272)  Podleski T, Changeux JP, Blumenthal R, Kasai M.
Conformational transitions in the course of membrane excitation.
In: Molecular properties of drug receptors. Ciba Found Symp: 197-228, 1970.
273)  Blumenthal R, Changeux JP, Lefever R.
Membrane excitability and dissipative instabilities.
J. Membr. Biol. 2: 351-74, 1970.
274)  Blumenthal R, Kedem O.
Flux ratio and driving forces in a model of active transport.
Biophys J. 9: 432-46, 1969.
275)  Blumenthal R, Katchalsky A.
The effect of the carrier association-dissociation rate on membrane permeation.
Biochim Biophys Acta. 173: 357-69, 1969.
276)  Blumenthal R, Kedem O.
The coupling of an enzymatic reaction to transmembrane flow of electriccurent in a synthetic 'active transport' system.
Biophys. J. 7: 735, 1967.
277)  Blumenthal R, Ginsburg BZ, Katchalsky A.
Thermodynamic and model treatment of active ion transport in erythrocytes (Proceedings 1st Intern Conference on Hemorheology).
Copley AL, eds.
. p. 91-110. [Meeting Proceeding]
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