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Our Science – Kelly Siebenlist Website

Kathleen Kelly Siebenlist, Ph.D.

Selected Publications

1)  Abou-Kheir WG, Hynes PG, Martin PL, Pierce R, Kelly K.
Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.
Stem Cells. 28: 2129-40, 2010.
[Journal]
2)  Martin P, Liu YN, Pierce R, Abou-Kheir W, Casey O, Seng V, Camacho D, Simpson RM, Kelly K.
Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.
Am. J. Pathol. 179: 422-35, 2011.
[Journal]
3)  Ward Y, Lake R, Yin JJ, Heger CD, Raffeld M, Goldsmith PK, Merino M, Kelly K.
LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells.
Cancer Res. 71: 7301-11, 2011.
[Journal]
4)  Liu YN, Abou-Kheir W, Yin JJ, Fang L, Hynes P, Casey O, Hu D, Wan Y, Seng V, Sheppard-Tillman H, Martin P, Kelly K.
Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition.
Mol. Cell. Biol. 32: 941-53, 2012.
[Journal]
5)  Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng S, Santoro M, Garcia-Rostan G, Kelly K.
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.
Oncogene. 32: 2726-38, 2013.
[Journal]
6)  Ying X, Xiang T, Li L, Su X, Shu X, Luo X, Huang J, Yuan Y, Peng W, Oberst M, Kelly K, Ren G, Tao Q.
DACT1, an antagonist to Wnt/beta-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer.
Breast Cancer Res. 15: R23, 2013.
[Journal]
7)  Liu Y, Yin JJ, Abou-Kheir W, Hynes PG, Casey OM, Fang L, Yi M, Stephens RM, Seng V, Sheppard-Tillman H, Martin P, Kelly K.
MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms.
Oncogene. 32: 296-306, 2013.
[Journal]
8)  Hynes PG, Kelly K.
Prostate cancer stem cells: The case for model systems.
J Carcinog. 11: 6, 2012.
[Journal]
9)  Xiang T, Li L, Yin X, Yuan C, Tan C, Su X, Xiong L, Putti TC, Oberst M, Kelly K, Ren G, Tao Q.
The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer.
PLoS ONE. 7: e29783, 2012.
[Journal]
10)  Casey OM, Fang L, Hynes PG, Abou-Kheir WG, Martin PL, Tillman HS, Petrovics G, Awwad HO, Ward Y, Lake R, Zhang L, Kelly K.
TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and Maintains Expression in a Castration Resistant Subpopulation.
PLoS ONE. 7: e41668, 2012.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 6/30/2014.