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Our Science – Kashlev Website

Mikhail Kashlev, Ph.D.

Selected Publications

1)  Vitiello CL, Kireeva ML, Lubkowska L, Kashlev M, Gottesman M.
Coliphage HK022 Nun protein inhibits RNA polymerase translocation.
Proc. Natl. Acad. Sci. U.S.A. 2014.
2)  Imashimizu M, Kashlev M.
Unveiling translocation intermediates of RNA polymerase.
Proc. Natl. Acad. Sci. U.S.A. 2014.
3)  Parks AR, Court C, Lubkowska L, Jin DJ, Kashlev M, Court DL.
Bacteriophage lambda N protein inhibits transcription slippage by Escherichia coli RNA polymerase.
Nucleic Acids Res. [Epub ahead of print], 2014.
4)  Afonin KA, Desai R, Viard M, Kireeva ML, Bindewald E, Case CL, Maciag AE, Kasprzak WK, Kim T, Sappe A, Stepler M, Kewalramani VN, Kashlev M, Blumenthal R, Shapiro BA.
Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities.
Nucleic Acids Res. 42: 2085-97, 2014.
5)  Afonin KA, Kasprzak WK, Bindewald E, Kireeva M, Viard M, Kashlev M, Shapiro BA.
In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles.
Acc. Chem. Res. [Epub ahead of print], 2014.
6)  Imashimizu M, Shimamoto N, Oshima T, Kashlev M.
Transcription elongation: Heterogeneous tracking of RNA polymerase and its biological implications.
Transcription. 5, 2014.
7)  Ishibashi T, Dangkulwanich M, Coello Y, Lionberger TA, Lubkowska L, Ponticelli AS, Kashlev M, Bustamante C.
Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics.
Proc. Natl. Acad. Sci. U.S.A. 111: 3419-24, 2014.
8)  Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante CJ.
Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism.
Elife. 2: e00971, 2013.
9)  Imashimizu M, Oshima T, Lubkowska L, Kashlev M.
Direct assessment of transcription fidelity by high-resolution RNA sequencing.
Nucleic Acids Res. 41: 9090-104, 2013.
10)  Kireeva ML, Kashlev M, Burton ZF.
RNA Polymerase Structure, Function, Regulation, Dynamics, Fidelity, and Roles in GENE EXPRESSION.
Chem. Rev. 113: 8325-30, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 5/27/2014.