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Our Science – Kashlev Website

Mikhail Kashlev, Ph.D.

Selected Publications

1)  Afonin KA, Desai R, Viard M, Kireeva ML, Bindewald E, Case CL, Maciag AE, Kasprzak WK, Kim T, Sappe A, Stepler M, Kewalramani VN, Kashlev M, Blumenthal R, Shapiro BA.
Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities.
Nucleic Acids Res. 2013.
2)  Dangkulwanich M, Ishibashi T, Liu S, Kireeva ML, Lubkowska L, Kashlev M, Bustamante CJ.
Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism.
Elife. 2: e00971, 2013.
3)  Imashimizu M, Oshima T, Lubkowska L, Kashlev M.
Direct assessment of transcription fidelity by high-resolution RNA sequencing.
Nucleic Acids Res. 2013.
4)  Kireeva ML, Kashlev M, Burton ZF.
RNA Polymerase Structure, Function, Regulation, Dynamics, Fidelity, and Roles in GENE EXPRESSION.
Chem. Rev. 113: 8325-30, 2013.
5)  Afonin KA, Kireeva M, Grabow WW, Kashlev M, Jaeger L, Shapiro BA.
Co-transcriptional assembly of chemically modified RNA nanoparticles functionalized with siRNAs.
Nano Lett. 12: 5192-5, 2012.
6)  Imashimizu M, Kireeva ML, Lubkowska L, Gotte D, Parks AR, Strathern JN, Kashlev M.
Intrinsic Translocation Barrier as an Initial Step in Pausing by RNA Polymerase II.
J. Mol. Biol. [Epub ahead of print], 2012.
7)  Zhou YN, Lubkowska L, Hui M, Court C, Chen S, Court DL, Strathern J, Jin DJ, Kashlev M.
Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in E. coli.
J. Biol. Chem. [Epub ahead of print], 2012.
8)  Kireeva ML, Opron K, Seibold SA, Domecq C, Cukier RI, Coulombe B, Kashlev M, Burton ZF.
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.
BMC Biophys. 5: 11, 2012.
9)  Bintu L, Ishibashi T, Dangkulwanich M, Wu YY, Lubkowska L, Kashlev M, Bustamante C.
Nucleosomal Elements that Control the Topography of the Barrier to Transcription.
Cell. 151: 738-49, 2012.
10)  Arnold JJ, Sharma SD, Feng JY, Ray AS, Smidansky ED, Kireeva ML, Cho A, Perry J, Vela JE, Park Y, Xu Y, Tian Y, Babusis D, Barauskus O, Peterson BR, Gnatt A, Kashlev M, Zhong W, Cameron CE.
Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides.
PLoS Pathog. 8: e1003030, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 11/15/2013.