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Our Science – Liu Website

Yongmin Liu, M.D., Ph.D.

Selected Publications

1)  Liu Y, Shim E, Nguyen P, Gibbons AT, Mitchell JB, Poirier MC.
Tempol Protects Cardiomyocytes from Nucleoside Reverse Transcriptase Inhibitor-Induced Mitochondrial Toxicity.
Toxicol. Sci. 2014.
[Journal]
2)  Olivero OA, Torres LR, Gorjifard S, Momot D, Marrogi E, Divi RL, Liu Y, Woodward RA, Sowers MJ, Poirier MC.
Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age.
J. Infect. Dis. 208: 244-8, 2013.
[Journal]
3)  Herman EH, Knapton A, Liu Y, Lipshultz SE, Estis J, Todd J, Woodward RA, Cochran T, Zhang J, Poirier MC.
The Influence of Age on Serum Concentrations of Cardiac Troponin I: Results in Rats, Monkeys, and Commercial Sera.
Toxicol Pathol. 2013.
[Journal]
4)  Liu Y, Nguyen P, Baris TZ, Poirier MC.
Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).
Cardiovasc. Toxicol. 12: 123-34, 2012.
[Journal]
5)  Liu Y, Borchert GL, Donald SP, Diwan BA, Anver M, Phang JM.
Proline Oxidase Functions as a Mitochondrial Tumor Suppressor in Human Cancers.
Cancer Res. 69: 6414-22, 2009.
[Journal]
6)  Surazynski A, Donald SP, Cooper SK, Whiteside MA, Salnikow K, Liu Y, Phang JM.
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Int. J. Cancer. 122: 1435-40, 2008.
[Journal]
7)  Phang JM, Pandhare J, Zabirnyk O, Liu Y.
PPARgamma and Proline Oxidase in Cancer.
PPAR Res. 2008: 542694, 2008.
[Journal]
8)  Liu Y, Borchert GL, Surazynski A, Phang JM.
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.
Oncogene. 27: 6729-37, 2008.
[Journal]
9)  Phang JM, Pandhare J, Liu Y.
The metabolism of proline as microenvironmental stress substrate.
J. Nutr. 138: 2008S-2015S, 2008.
[Journal]
10)  Phang JM, Donald SP, Pandhare J, Liu Y.
The metabolism of proline, a stress substrate, modulates carcinogenic pathways.
Amino Acids. 35: 681-90, 2008.
[Journal]
11)  Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM.
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling.
Oncogene. 25: 5640-7, 2006.
[Journal]
12)  Liu Y, Borchert GL, Donald SP, Surazynski A, Hu CA, Weydert CJ, Oberley LW, Phang JM.
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.
Carcinogenesis. 26: 1335-42, 2005.
[Journal]
13)  Surazynski A, Liu Y, Miltyk W, Phang JM.
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation.
J. Cell. Biochem. 96: 1086-94, 2005.
[Journal]
14)  Liu Y, Lu C, Shen Q, Munoz-Medellin D, Kim H, Brown PH.
AP-1 blockade in breast cancer cells causes cell cycle arrest by suppressing G1 cyclin expression and reducing cyclin-dependent kinase activity.
Oncogene. 23: 8238-46, 2004.
[Journal]
15)  Liu Y, Borchert GL, Phang JM.
Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells.
J. Biol. Chem. 279: 18694-700, 2004.
[Journal]
16)  Liu Y, Ludes-Meyers J, Zhang Y, Munoz-Medellin D, Kim HT, Lu C, Ge G, Schiff R, Hilsenbeck SG, Osborne CK, Brown PH.
Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth.
Oncogene. 21: 7680-9, 2002.
[Journal]
17)  Ludes-Meyers JH, Liu Y, Muñoz-Medellin D, Hilsenbeck SG, Brown PH.
AP-1 blockade inhibits the growth of normal and malignant breast cells.
Oncogene. 20: 2771-80, 2001.
[Journal]
18)  Liu Y, McKalip A, Herman B.
Human papillomavirus type 16 E6 and HPV-16 E6/E7 sensitize human keratinocytes to apoptosis induced by chemotherapeutic agents: roles of p53 and caspase activation.
J. Cell. Biochem. 78: 334-49, 2000.
[Journal]
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This page was last updated on 4/10/2014.