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Our Science – Liu Website

Yongmin Liu, M.D., Ph.D.

Selected Publications

1)  Liu Y, Shim E, Nguyen P, Gibbons AT, Mitchell JB, Poirier MC.
Tempol Protects Cardiomyocytes from Nucleoside Reverse Transcriptase Inhibitor-Induced Mitochondrial Toxicity.
Toxicol. Sci. 2014.
2)  Olivero OA, Torres LR, Gorjifard S, Momot D, Marrogi E, Divi RL, Liu Y, Woodward RA, Sowers MJ, Poirier MC.
Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age.
J. Infect. Dis. 208: 244-8, 2013.
3)  Herman EH, Knapton A, Liu Y, Lipshultz SE, Estis J, Todd J, Woodward RA, Cochran T, Zhang J, Poirier MC.
The Influence of Age on Serum Concentrations of Cardiac Troponin I: Results in Rats, Monkeys, and Commercial Sera.
Toxicol Pathol. 2013.
4)  Liu Y, Nguyen P, Baris TZ, Poirier MC.
Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).
Cardiovasc. Toxicol. 12: 123-34, 2012.
5)  Liu Y, Borchert GL, Donald SP, Diwan BA, Anver M, Phang JM.
Proline Oxidase Functions as a Mitochondrial Tumor Suppressor in Human Cancers.
Cancer Res. 69: 6414-22, 2009.
6)  Surazynski A, Donald SP, Cooper SK, Whiteside MA, Salnikow K, Liu Y, Phang JM.
Extracellular matrix and HIF-1 signaling: the role of prolidase.
Int. J. Cancer. 122: 1435-40, 2008.
7)  Phang JM, Pandhare J, Zabirnyk O, Liu Y.
PPARgamma and Proline Oxidase in Cancer.
PPAR Res. 2008: 542694, 2008.
8)  Liu Y, Borchert GL, Surazynski A, Phang JM.
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.
Oncogene. 27: 6729-37, 2008.
9)  Phang JM, Pandhare J, Liu Y.
The metabolism of proline as microenvironmental stress substrate.
J. Nutr. 138: 2008S-2015S, 2008.
10)  Phang JM, Donald SP, Pandhare J, Liu Y.
The metabolism of proline, a stress substrate, modulates carcinogenic pathways.
Amino Acids. 35: 681-90, 2008.
11)  Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM.
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling.
Oncogene. 25: 5640-7, 2006.
12)  Liu Y, Borchert GL, Donald SP, Surazynski A, Hu CA, Weydert CJ, Oberley LW, Phang JM.
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.
Carcinogenesis. 26: 1335-42, 2005.
13)  Surazynski A, Liu Y, Miltyk W, Phang JM.
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation.
J. Cell. Biochem. 96: 1086-94, 2005.
14)  Liu Y, Lu C, Shen Q, Munoz-Medellin D, Kim H, Brown PH.
AP-1 blockade in breast cancer cells causes cell cycle arrest by suppressing G1 cyclin expression and reducing cyclin-dependent kinase activity.
Oncogene. 23: 8238-46, 2004.
15)  Liu Y, Borchert GL, Phang JM.
Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells.
J. Biol. Chem. 279: 18694-700, 2004.
16)  Liu Y, Ludes-Meyers J, Zhang Y, Munoz-Medellin D, Kim HT, Lu C, Ge G, Schiff R, Hilsenbeck SG, Osborne CK, Brown PH.
Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth.
Oncogene. 21: 7680-9, 2002.
17)  Ludes-Meyers JH, Liu Y, Muñoz-Medellin D, Hilsenbeck SG, Brown PH.
AP-1 blockade inhibits the growth of normal and malignant breast cells.
Oncogene. 20: 2771-80, 2001.
18)  Liu Y, McKalip A, Herman B.
Human papillomavirus type 16 E6 and HPV-16 E6/E7 sensitize human keratinocytes to apoptosis induced by chemotherapeutic agents: roles of p53 and caspase activation.
J. Cell. Biochem. 78: 334-49, 2000.
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This page was last updated on 4/10/2014.