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Our Science – Lipkowitz Website

Stanley Lipkowitz, M.D., Ph.D.

Selected Publications

1)  Keane MM, Ettenberg SA, Nau MM, Russell EK, Lipkowitz S.
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines.
Cancer Res. 59: 734-41, 1999.
2)  Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, Lipkowitz S, Yarden Y.
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.
Mol. Cell. 4: 1029-40, 1999.
3)  Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, Penninger JM.
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
Nature. 403: 211-6, 2000.
4)  Ettenberg SA, Magnifico A, Cuello M, Nau MM, Rubinstein YR, Yarden Y, Weissman AM, Lipkowitz S.
Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex.
J Biol Chem. 276: 27677-84, 2001.
5)  Rahman M, Davis SR, Pumphrey JG, Bao J, Nau MM, Meltzer PS, Lipkowitz S.
TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype.
Breast Cancer Res. Treat. 113: 217-230, 2009.
6)  Qiao G, Ying H, Zhao Y, Liang Y, Guo H, Shen H, Li Z, Solway J, Tao E, Chiang YJ, Lipkowitz S, Penninger JM, Langdon WY, Zhang J.
E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation.
Cell Rep. 6: 709-23, 2014.
7)  Kales SC, Nau MM, Merchant AS, Lipkowitz S.
Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A.
PLoS ONE. 9: e87116, 2014.
8)  Garimella SV, Gehlhaus K, Dine JL, Pitt JJ, Grandin M, Chakka S, Nau MM, Caplen NJ, Lipkowitz S.
Identification of novel molecular regulators of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.
Breast Cancer Res. 16: R41, 2014.
9)  Veselits M, Tanaka A, Lipkowitz S, O'Neill S, Sciammas R, Finnegan A, Zhang J, Clark MR.
Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes.
PLoS ONE. 9: e89792, 2014.
10)  Wedam S, Lipkowitz S.
Yang S, Dancey J, eds.
HER-2 as a prognostic and predictive biomarker in cancer. In: Handbook of therapuetic biomarkers in cancer.
Singapore: Pan Stanford Publishing; 2013. p. 77-120 [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 6/20/2014.