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Our Science – Basrai Website

Munira A. Basrai, Ph.D.

Selected Publications

1)  Ainsworth WB, Hughes BT, Au WC, Sakelaris S, Kerscher O, Benton MG, Basrai MA.
Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p-Rnr4p.
Biochem. Biophys. Res. Commun. 2013.
In Press. [Journal]
2)  Mishra PK, Ottmann AR, Basrai MA.
Structural Integrity of Centromeric Chromatin and Faithful Chromosome Segregation Requires Pat1.
Genetics. 2013.
In Press. [Journal]
3)  Au WC, Dawson AR, Rawson DW, Taylor SB, Baker RE, Basrai MA.
A Novel Role of the N-Terminus of Budding Yeast Histone H3 Variant Cse4 in Ubiquitin-Mediated Proteolysis.
Genetics. [Epub ahead of print], 2013.
[Journal]
4)  Choy JS, O'Toole E, Schuster BM, Crisp MJ, Karpova TS, McNally JG, Winey M, Gardner MK, Basrai MA.
Genome-wide haploinsufficiency screen reveals a novel role for ?-TuSC in spindle organization and genome stability.
Mol. Biol. Cell. 24: 2753-63, 2013.
[Journal]
5)  Boeckmann L, Takahashi Y, Au W, Mishra PK, Choy JS, Dawson AR, Szeto MY, Waybright TJ, Heger C, McAndrew C, Goldsmith PK, Veenstra TD, Baker RE, Basrai MA.
Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae.
Mol. Biol. Cell. 24: 2034-44, 2013.
[Journal]
6)  Lai X, Beilharz T, Au WC, Hammet A, Preiss T, Basrai MA, Heierhorst J.
Yeast hEST1A/B (SMG5/6)-like Proteins Contribute to Environment-Sensing Adaptive Gene Expression Responses.
G3 (Bethesda). 2013.
[Journal]
7)  Choy JS, Mishra PK, Au W, Basrai MA.
Insights into assembly and regulation of centromeric chromatin in Saccharomyces cerevisiae.
Biochim Biophys Acta. [Epub ahead of print], 2012.
[Journal]
8)  Stirling PC, Crisp MJ, Basrai MA, Tucker CM, Dunham MJ, Spencer FA, Hieter P.
Mutability and mutational spectrum of chromosome transmission fidelity genes.
Chromosoma. 121: 263-75, 2012.
[Journal]
9)  Choy JS, Acuna R, Au W, Basrai MA.
A Role for Histone H4K16 Hypoacetylation in Saccharomyces cerevisiae Kinetochore Function.
Genetics. 189: 11-21, 2011.
[Journal]
10)  Magtanong L, Ho CH, Barker SL, Jiao W, Baryshnikova A, Bahr S, Smith AM, Heisler LE, Choy JS, Kuzmin E, Andrusiak K, Kobylianski A, Li Z, Costanzo M, Basrai MA, Giaever G, Nislow C, Andrews B, Boone C.
Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.
Nat Biotechnol. 29: 505-11, 2011.
[Journal]
11)  Mishra PK, Au WC, Choy JS, Kuich PH, Baker RE, Foltz DR, Basrai MA.
Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells.
PLoS Genet. 7: e1002303, 2011.
[Journal]
12)  Guo Y, Au WC, Shakoury-Elizeh M, Protchenko O, Basrai M, Prinz WA, Philpott CC.
Phosphatidylserine is involved in the ferrichrome-induced plasma membrane trafficking of Arn1 in Saccharomyces cerevisiae.
J. Biol. Chem. 285: 39564-73, 2010.
[Journal]
13)  Deng Y, Guo Y, Watson H, Au WC, Shakoury-Elizeh M, Basrai MA, Bonifacino JS, Philpott CC.
Gga2 Mediates Sequential Ubiquitin-independent and Ubiquitin-dependent Steps in the Trafficking of ARN1 from the trans-Golgi Network to the Vacuole.
J. Biol. Chem. 284: 23830-41, 2009.
[Journal]
14)  Au WC, Crisp MJ, DeLuca SZ, Rando OJ, Basrai MA.
Altered dosage and mislocalization of histone H3 and Cse4p lead to chromosome loss in Saccharomyces cerevisiae.
Genetics. 179: 263-75, 2008.
[Journal]
15)  Harper NC, Al-Greene NT, Basrai MA, Belanger KD.
Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae.
Curr. Genet. 53: 95-105, 2008.
[Journal]
16)  Kastenmayer JP, Ni L, Chu A, Kitchen LE, Au WC, Yang H, Carter CD, Wheeler D, Davis RW, Boeke JD, Snyder MA, Basrai MA.
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.
Genome Res. 16: 365-73, 2006.
[Journal]
17)  Wang BD, Eyre D, Basrai M, Lichten M, Strunnikov A.
Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome.
Mol. Cell. Biol. 25: 7216-25, 2005.
[Journal]
18)  Carter CD, Kitchen LE, Au WC, Babic CM, Basrai MA.
Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors.
Mol. Cell. Biol. 25: 10273-85, 2005.
[Journal]
19)  Brannon AR, Maresca JA, Boeke JD, Basrai MA, McBride AA.
Reconstitution of papillomavirus E2-mediated plasmid maintenance in Saccharomyces cerevisiae by the Brd4 bromodomain protein.
Proc Natl Acad Sci U S A. 102: 2998-3003, 2005.
[Journal]
20)  Kastenmayer JP, Lee MS, Hong AL, Spencer FA, Basrai MA.
The C-Terminal Half of Saccharomyces cerevisiae Mad1p Mediates Spindle Checkpoint Function, Chromosome Transmission Fidelity and CEN Association.
Genetics. 170: 509-17, 2005.
[Journal]
21)  Crotti LB, Basrai MA.
Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae.
EMBO J. 23: 1804-14, 2004.
[Journal]
22)  Kerscher O, Crotti LB, Basrai MA.
Recognizing chromosomes in trouble: Association of the spindle checkpoint protein Bub3-GFP with altered kinetochores and a unique defective centromere.
Mol. Cell. Biol. 23: 6406-6418, 2003.
[Journal]
23)  Iouk T, Kerscher O, Scott RJ, Basrai MA, Wozniak RW.
The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint.
J Cell Biol. 159: 807-19, 2002.
[Journal]
24)  Basrai MA, Hieter P.
Transcriptome analysis of Saccharomyces cerevisiae using serial analysis of gene expression.
Methods Enzymol. 350: 414-444, 2002.
[Journal]
25)  Kerscher O, Hieter P, Winey M, Basrai MA.
Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation.
Genetics. 157: 1543-1553, 2001.
[Journal]
26)  Basrai MA, Velculescu VE, Kinzler KW, Hieter P.
NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.
Mol Cell Biol. 19: 7041-7049, 1999.
[Journal]
27)  Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS.
Characterization of the CHD family of proteins.
Proc Natl Acad Sci U S A. 94: 11472-7, 1997.
[Journal]
28)  Velculescu VE, Zhang L, Zhou W, Vogelstein J, Basrai MA, Bassett DE, Hieter P, Vogelstein B, Kinzler KW.
Characterization of the yeast transcriptome.
Cell. 88: 243-51, 1997.
[Journal]
29)  Basrai MA, Hieter P, Boeke JD.
Small open reading frames: beautiful needles in the haystack.
Genome Res. 7: 768-71, 1997.
[Journal]
30)  Bassett DE, Basrai MA, Connelly C, Hyland KM, Kitagawa K, Mayer ML, Morrow DM, Page AM, Resto VA, Skibbens RV, Hieter P.
Exploiting the complete yeast genome sequence.
Curr Opin Genet Dev. 6: 763-6, 1996.
[Journal]
31)  Basrai MA, Kingsbury J, Koshland D, Spencer F, Hieter P.
Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae.
Mol Cell Biol. 16: 2838-2847, 1996.
[Journal]
32)  Hartzog GA, Basrai MA, Ricupero-Hovasse SL, Hieter P, Winston F.
Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.
Mol Cell Biol. 16: 2848-56, 1996.
[Journal]
33)  Basrai MA, Lubkowitz MA, Perry JR, Miller D, Krainer E, Naider F, Becker JM.
Cloning of a Candida albicans peptide transport gene.
Microbiology (Reading, Engl.). 141 ( Pt 5): 1147-56, 1995.
[Journal]
34)  Basrai MA, Hieter P.
Is there a unique form of chromatin at the Saccharomyces cerevisiae centromeres?.
Bioessays. 17: 669-72, 1995.
[Journal]
35)  Perry JR, Basrai MA, Steiner HY, Naider F, Becker JM.
Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene.
Mol. Cell. Biol. 14: 104-15, 1994.
[Journal]
36)  Basrai MA, Zhang HL, Miller D, Naider F, Becker JM.
Toxicity of oxalysine and oxalysine-containing peptides against Candida albicans: regulation of peptide transport by amino acids.
J. Gen. Microbiol. 138: 2353-62, 1992.
[Journal]
37)  Basrai MA, Naider F, Becker JM.
Internalization of lucifer yellow in Candida albicans by fluid phase endocytosis.
J. Gen. Microbiol. 136: 1059-65, 1990.
[Journal]
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This page was last updated on 9/13/2013.