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Our Science – Aplan Website

Peter D. Aplan, M.D.

Selected Publications

1)  Bailey EJ, Duffield AS, Greenblatt SM, Aplan PD, Small D.
Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.
Comp. Med. 63: 218-26, 2013.
[Journal]
2)  Lacombe J, Krosl G, Tremblay M, Gerby B, Martin R, Aplan PD, Lemieux S, Hoang T.
Genetic interaction between Kit and Scl.
Blood. 122: 1150-61, 2013.
[Journal]
3)  Goldberg L, Tijssen MR, Birger Y, Hannah RL, Kinston SJ, Schütte J, Beck D, Knezevic K, Schiby G, Jacob-Hirsch J, Biran A, Kloog Y, Marcucci G, Bloomfield CD, Aplan PD, Pimanda JE, Göttgens B, Izraeli S.
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.
Blood. 2013.
[Journal]
4)  Beachy SH, Onozawa M, Silverman D, Chung YJ, Rivera MM, Aplan PD.
Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia.
Exp. Hematol. [Epub ahead of print], 2013.
[Journal]
5)  Levens D, Aplan PD.
Notching up MYC gives a LIC.
Cell Stem Cell. 13: 8-9, 2013.
[Journal]
6)  Chung YJ, Robert C, Gough SM, Rassool FV, Aplan PD.
Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome.
Leuk. Res. 2013.
[Journal]
7)  Métais JY, Winkler T, Geyer JT, Calado RT, Aplan PD, Eckhaus MA, Dunbar CE.
BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.
PLoS ONE. 7: e48267, 2012.
[Journal]
8)  Gough SM, Chung YJ, Aplan PD.
Depletion of Cytotoxic T-Cells Does Not Protect NUP98-HOXD13 Mice from Myelodysplastic Syndrome but Reveals a Modest Tumor Immunosurveillance Effect.
PLoS ONE. 7: e36876, 2012.
[Journal]
9)  Beachy SH, Onozawa M, Chung YJ, Slape C, Bilke S, Francis P, Pineda M, Walker RL, Meltzer P, Aplan PD.
Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines and peripheral T-cell lymphoma.
Blood. 2012.
[Journal]
10)  Novak RL, Harper DP, Caudell D, Slape C, Beachy SH, Aplan PD.
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes.
Exp. Hematol. 40: 1016-27, 2012.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 9/13/2013.