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Our Science – Aplan Website

Peter D. Aplan, M.D.

Selected Publications

1)  Beachy SH, Onozawa M, Silverman D, Chung YJ, Rivera MM, Aplan PD.
Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia.
Exp. Hematol. [Epub ahead of print], 2013.
[Journal]
2)  Métais JY, Winkler T, Geyer JT, Calado RT, Aplan PD, Eckhaus MA, Dunbar CE.
BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.
PLoS ONE. 7: e48267, 2012.
[Journal]
3)  Gough SM, Chung YJ, Aplan PD.
Depletion of Cytotoxic T-Cells Does Not Protect NUP98-HOXD13 Mice from Myelodysplastic Syndrome but Reveals a Modest Tumor Immunosurveillance Effect.
PLoS ONE. 7: e36876, 2012.
[Journal]
4)  Beachy SH, Onozawa M, Chung YJ, Slape C, Bilke S, Francis P, Pineda M, Walker RL, Meltzer P, Aplan PD.
Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines and peripheral T-cell lymphoma.
Blood. 2012.
[Journal]
5)  Novak RL, Harper DP, Caudell D, Slape C, Beachy SH, Aplan PD.
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes.
Exp. Hematol. 40: 1016-27, 2012.
[Journal]
6)  Onozawa M, Aplan PD.
Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.
Genes Chromosomes Cancer. 51: 525-35, 2012.
[Journal]
7)  Slape CI, Saw J, Jowett JB, Aplan PD, Strasser A, Jane SM, Curtis DJ.
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome.
Blood. 2012.
[Journal]
8)  Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D.
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.
Blood. 119: 2883-94, 2012.
[Journal]
9)  Xu H, Menendez S, Schlegelberger B, Bae N, Aplan PD, Göhring G, Deblasio TR, Nimer SD.
Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.
Blood. 120: 3089-97, 2012.
[Journal]
10)  Slape C, Aplan P.
Schwab M, eds.
Retroviral Insertional Mutagenesis. In: Encyclopedia of Cancer. Volume 2.
Berlin: Springer-Verlag; 2011. p. 1767 [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 4/5/2013.