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Our Science – Udey Website

Mark C. Udey, M.D., Ph.D.

Selected Publications

1)  Tang A, Amagai M, Granger LG, Stanley JR, Udey MC.
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin.
Nature. 361: 82-5, 1993.
[Journal]
2)  Borkowski TA, Letterio JJ, Farr AG, Udey MC.
A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells.
J. Exp. Med. 184: 2417-22, 1996.
[Journal]
3)  Nagao K, Ginhoux F, Leitner WW, Motegi S, Bennett CL, Clausen BE, Merad M, Udey MC.
Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions.
Proc. Natl. Acad. Sci. U.S.A. 106: 3312-7, 2009.
[Journal]
4)  Gaiser MR, Lämmermann T, Feng X, Igyarto BZ, Kaplan DH, Tessarollo L, Germain RN, Udey MC.
Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo.
Proc. Natl. Acad. Sci. U.S.A. 109: E889-97, 2012.
[Journal]
5)  Wu CJ, Mannan P, Lu M, Udey MC.
Epithelial Cell Adhesion Molecule (EpCAM) Regulates Claudin Dynamics and Tight Junctions.
J. Biol. Chem. 288: 12253-68, 2013.
[Journal]
6)  Hai H, Wang H, Pisitkuni P, Kim J, Tassi I, Tang W, Morasso M, Udey M, Siebenlist U.
IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms.
Proc Natl Acad Sci USA. 2014.
In Press. [Journal]
7)  Colmont CS, Ketah AB, Errington RJ, Reed SH, Udey MC, Patel GK.
Human basal cell carcinoma tumor-initiating cells are resistant to etoposide.
J. Invest. Dermatol. 134: 867-70, 2014.
[Journal]
8)  Uchiyama A, Yamada K, Ogino S, Yokoyama Y, Takeuchi Y, Udey MC, Ishikawa O, Motegi S.
MFG-E8 Regulates Angiogenesis in Cutaneous Wound Healing.
Am. J. Pathol. 184: 1981-90, 2014.
[Journal]
9)  Abe T, Shin J, Hosur K, Udey MC, Chavakis T, Hajishengallis G.
Regulation of Osteoclast Homeostasis and Inflammatory Bone Loss by MFG-E8.
J. Immunol. [Epub ahead of print], 2014.
[Journal]
10)  Colmont CS, Benketah A, Reed SH, Hawk NV, Telford WG, Ohyama M, Udey MC, Yee CL, Vogel JC, Patel GK.
CD200-expressing human basal cell carcinoma cells initiate tumor growth.
Proc. Natl. Acad. Sci. U.S.A. 110: 1434-9, 2013.
[Journal]
11)  Mohammed J, Gunderson AJ, Khong HH, Koubek RD, Udey MC, Glick AB.
TGFß1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity.
J. Invest. Dermatol. 133: 135-43, 2013.
[Journal]
12)  Nagao K, Kobayashi T, Moro K, Ohyama M, Adachi T, Kitashima DY, Ueha S, Horiuchi K, Tanizaki H, Kabashima K, Kubo A, Cho YH, Clausen BE, Matsushima K, Suematsu M, Furtado GC, Lira SA, Farber JM, Udey MC, Amagai M.
Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.
Nat. Immunol. 13: 744-52, 2012.
[Journal]
13)  Hwang J, Kita R, Kwon HS, Choi EH, Lee SH, Udey MC, Morasso MI.
Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation.
Proc. Natl. Acad. Sci. U.S.A. 108: 11566-71, 2011.
[Journal]
14)  Motegi S, Leitner WW, Lu M, Tada Y, Sardy M, Wu C, Chavakis T, Udey MC.
Pericyte-Derived MFG-E8 Regulates Pathologic Angiogenesis.
Arterioscler. Thromb. Vasc. Biol. 31: 2024-34, 2011.
[Journal]
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This page was last updated on 7/22/2014.