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Our Science – Hodes Website

Richard J. Hodes, M.D.

Selected Publications

1)  Bowen S, Sun P, Livak F, Sharrow S, Hodes RJ.
A novel T cell subset with trans-rearranged V?-Cß TCRs shows Vß expression is dispensable for lineage choice and MHC restriction.
J. Immunol. 192: 169-77, 2014.
[Journal]
2)  Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ.
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
J. Immunol. 192: 630-40, 2014.
[Journal]
3)  Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ.
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.
Proc. Natl. Acad. Sci. U.S.A. 110: 21107-12, 2013.
[Journal]
4)  Bowen S, Wangsa D, Ried T, Livak F, Hodes RJ.
Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes.
Nucleic Acids Res. [Epub ahead of print], 2013.
[Journal]
5)  Hathcock KS, Bowen S, Livak F, Hodes RJ.
ATM influences the efficiency of TCRß rearrangement, subsequent TCRß-dependent T cell development, and generation of the pre-selection TCRß CDR3 repertoire.
PLoS ONE. 8: e62188, 2013.
[Journal]
6)  Chiang YJ, Hemann MT, Hathcock KS, Tessarollo L, Feigenbaum L, Hahn WC, Hodes RJ.
Expression of telomerase RNA template (mTR), but not telomerase reverse transcriptase (mTERT), is limiting for telomere length maintenance in vivo.
Molecular and Cellular Biology. 24: 7024-7031, 2004.
[Journal]
7)  Chiang YJ, Calado RT, Hathcock KS, Lansdorp PM, Young NS, Hodes RJ.
Telomere length is inherited with resetting of the telomere set-point.
Proceedings of the National Academy of Sciences of the United States of America. 2010.
[Journal]
8)  Vacchio MS, Hodes RJ.
CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells.
J Exp Med. 197: 19-26, 2003.
[Journal]
9)  Vacchio MS, Olaru A, Livak F, Hodes RJ.
ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor {alpha} locus coding end breaks.
Proc Natl Acad Sci U S A. 2007.
[Journal]
10)  Hodes RJ, Hathcock KS, Weng NP.
Telomeres in T and B cells.
Nat Rev Immunol. 2: 699-706, 2002.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 4/5/2014.