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Our Science – Samelson Website

Lawrence E. Samelson, M.D.

Selected Publications

1)  Kortum RL, Rouquette-Jazdanian AK, Miyaji M, Merrill RK, Markegard E, Pinski JM, Wesselink A, Nath NN, Alexander CP, Li W, Kedei N, Roose JP, Blumberg PM, Samelson LE, Sommers CL.
A Phospholipase C-gamma1-Independent, RasGRP1-ERK-Dependent Pathway Drives Lymphoproliferative Disease in Linker for Activation of T Cells-Y136F Mutant Mice.
J. Immunol. 190: 147-58, 2013.
[Journal]
2)  Balagopalan L, Barr VA, Kortum RL, Park AK, Samelson LE.
Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling.
J. Immunol. 190: 3849-53, 2013.
[Journal]
3)  Kunii N, Zhao Y, Jiang S, Liu X, Scholler J, Balagopalan L, Samelson LE, Milone MC, June CH.
Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.
Hum. Gene Ther. 24: 27-37, 2013.
[Journal]
4)  Kortum RL, Rouquette-Jazdanian AK, Samelson LE.
Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells.
Trends Immunol. [Epub ahead of print], 2013.
[Journal]
5)  Sherman E, Barr V, Samelson LE.
Super-resolution characterization of TCR-dependent signaling clusters.
Immunol. Rev. 251: 21-35, 2013.
[Journal]
6)  Kortum RL, Sommers CL, Pinski JM, Alexander CP, Merrill RK, Li W, Love PE, Samelson LE.
Deconstructing Ras signaling in the thymus.
Mol Cell Biol. 32: 2748-59, 2012.
[Journal]
7)  Lesourne R, Zvezdova E, Song KD, El-Khoury D, Uehara S, Barr VA, Samelson LE, Love PE.
Interchangeability of themis1 and themis2 in thymocyte development reveals two related proteins with conserved molecular function.
J. Immunol. 189: 1154-61, 2012.
[Journal]
8)  Rouquette-Jazdanian AK, Sommers CL, Kortum RL, Morrison DK, Samelson LE.
LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.
Mol. Cell. 48: 298-312, 2012.
[Journal]
9)  Sherman E, Barr VA, Samelson LE.
Resolving multi-molecular protein interactions by photoactivated localization microscopy.
Methods. 59: 261-9, 2012.
[Journal]
10)  Balagopalan L, Ashwell BA, Bernot KM, Akpan IO, Quasba N, Barr VA, Samelson LE.
Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation.
Proc. Natl. Acad. Sci. U.S.A. 108: 2885-90, 2011.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 4/29/2013.