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Kathrin Muegge, M.D.

Selected Publications

1)  Yu W, Briones V, Lister R, McIntosh C, Han Y, Lee EY, Ren J, Terashima M, Leighty RM, Ecker JR, Muegge K.
CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity.
Proc. Natl. Acad. Sci. U.S.A. 111: 5890-5, 2014.
2)  Briones V, Muegge K.
The ghosts in the machine: DNA methylation and the mystery of differentiation.
Biochim Biophys Acta. 1819: 757-62, 2012.
3)  von Eyss B, Maaskola J, Memczak S, Möllmann K, Schuetz A, Loddenkemper C, Tanh MD, Otto A, Muegge K, Heinemann U, Rajewsky N, Ziebold U.
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
EMBO J. 31: 972-85, 2012.
4)  Tao Y, Xi S, Shan J, Maunakea A, Che A, Briones V, Lee EY, Geiman T, Huang J, Stephens R, Leighty RM, Zhao K, Muegge K.
Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences.
Proc. Natl. Acad. Sci. U.S.A. 108: 5626-31, 2011.
5)  Zeng W, Baumann C, Schmidtmann A, Honaramooz A, Tang L, Bondareva A, Dores C, Fan T, Xi S, Geiman T, Rathi R, de Rooij D, De La Fuente R, Muegge K, Dobrinski I.
Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes.
Biol. Reprod. 84: 1235-41, 2011.
6)  Tao Y, Liu S, Briones V, Geiman TM, Muegge K.
Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS.
Nucleic Acids Res. 39: 9508-20, 2011.
7)  Geiman TM, Muegge K.
DNA methylation in early development.
Mol. Reprod. Dev. 77: 105-13, 2010.
8)  Tao Y, Xi S, Briones V, Muegge K.
Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation.
PLoS ONE. 5: e9163, 2010.
9)  Xi S, Geiman TM, Briones V, Tao YG, Xu H, Muegge K.
Lsh Participates in DNA Methylation and Silencing of Stem Cell Genes.
Stem Cells. 27: 2691-702, 2009.
10)  Baumann C, Schmidtmann A, Muegge K, De La Fuente R.
Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia.
BMC Mol. Biol. 9: 29, 2008.
Click Here to View Expanded Bibliography.

This page was last updated on 5/13/2014.