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Our Science – Widemann Website

Brigitte C. Widemann, M.D.

Selected Publications

1)  Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H.
CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.
Am. J. Med. Genet. A. 164A: 563-78, 2014.
2)  Widemann BC, Schwartz S, Jayaprakash N, Christensen R, Pui CH, Chauhan N, Daugherty C, King TR, Rush JE, Howard SC.
Efficacy of glucarpidase (carboxypeptidase g2) in patients with acute kidney injury after high-dose methotrexate therapy.
Pharmacotherapy. 34: 427-39, 2014.
3)  Widemann BC, Dombi E, Gillespie A, Wolters PL, Belasco J, Goldman S, Korf BR, Solomon J, Martin S, Salzer W, Fox E, Patronas N, Kieran MW, Perentesis JP, Reddy A, Wright JJ, Kim A, Steinberg SM, Balis FM.
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
Neuro-oncology. 16: 707-18, 2014.
4)  Widemann BC, Babovic-Vuksanovic D, Dombi E, Wolters PL, Goldman S, Martin S, Goodwin A, Goodspeed W, Kieran MW, Cohen B, Blaney SM, King A, Solomon J, Patronas N, Balis FM, Fox E, Steinberg SM, Packer RJ.
Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
Pediatr Blood Cancer. [Epub ahead of print], 2014.
5)  Dagalakis U, Lodish M, Dombi E, Sinaii N, Sabo J, Baldwin A, Steinberg SM, Stratakis CA, Widemann BC.
Puberty and plexiform neurofibroma tumor growth in patients with neurofibromatosis type I.
J. Pediatr. 164: 620-4, 2014.
6)  Nella A, Lodish M, Fox E, Balis F, Quezado M, Whitcomb P, Derdak J, Kebebew E, Widemann B, Stratakis C.
Vandetanib successfully controls medullary thyroid cancer-related Cushing syndrome in an adolescent patient.
J. Clin. Endocrinol. Metab. jc20134340, 2014.
7)  Plotkin SR, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL, Widemann BC.
Achieving consensus for clinical trials: the REiNS International Collaboration.
Neurology. 81: S1-5, 2013.
8)  Widemann BC, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL, Plotkin SR.
Conclusions and future directions for the REiNS International Collaboration.
Neurology. 81: S41-4, 2013.
9)  McCully CM, Pastakia D, Bacher J, Thomas ML, Steffen-Smith EA, Saleem K, Murphy RF, Walbridge S, Brinster L, Widemann BC, Warren KE.
Model for concomitant microdialysis sampling of the pons and cerebral cortex in rhesus macaques (Macaca mulatta).
Comp. Med. 63: 355-60, 2013.
10)  Koethe Y, Widemann BC, Hajjar F, Wood BJ, Venkatesan AM.
PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1.
Pediatr Blood Cancer. 60: E166-9, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 5/20/2014.