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Our Science – Thiele Website

Carol J. Thiele, Ph.D.

Selected Publications

1)  Liu Z, Rader J, He S, Phung T, Thiele CJ.
CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity.
Cell Cycle. 12, 2013.
2)  Yan S, Li Z, Thiele CJ.
Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo.
Oncotarget. 4: 433-45, 2013.
3)  He S, Liu Z, Oh DY, Thiele CJ.
MYCN and the epigenome.
Front Oncol. 3: 1, 2013.
4)  Liu Z, Thiele CJ.
ALK and MYCN: when two oncogenes are better than one.
Cancer Cell. 21: 325-6, 2012.
5)  Virden RA, Thiele CJ, Liu Z.
Characterization of critical domains within the tumor suppressor CASZ1 required for transcriptional regulation and growth suppression.
Mol. Cell. Biol. 32: 1518-28, 2012.
6)  Li Z, Yan S, Attayan N, Ramalingam S, Thiele CJ.
Combination of an Allosteric Akt Inhibitor MK-2206 with Etoposide or Rapamycin Enhances the Antitumor Growth Effect in Neuroblastoma.
Clin. Cancer Res. 18: 3603-15, 2012.
7)  Lawlor ER, Thiele CJ.
Epigenetic changes in pediatric solid tumors: promising new targets.
Clin. Cancer Res. 18: 2768-79, 2012.
8)  Wang C, Liu Z, Woo CW, Li Z, Wang L, Wei JS, Marquez VE, Bates SE, Jin Q, Khan J, Ge K, Thiele CJ.
EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR.
Cancer Res. 72: 315-24, 2012.
9)  Thiele CJ, Cohn SL.
Genetically InFormed Therapies--A.
Clin. Cancer Res. 18: 2735-9, 2012.
10)  Liu Z, Yang X, Li Z, McMahon C, Sizer C, Barenboim-Stapleton L, Bliskovsky V, Mock B, Ried T, London WB, Maris J, Khan J, Thiele CJ.
CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression.
Cell Death Differ. 18: 1174-83, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 7/17/2013.