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Our Science – Hatfield Website

Dolph L. Hatfield, Ph.D.

Selected Publications

1)  Xu X, Carlson BA, Mix H, Zhang Y, Saira K, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL.
Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes.
PLoS Biol. 5: e4, 2007.
2)  Xu XM, Turanov AA, Carlson BA, Yoo MH, Everley RA, Nandakumar R, Sorokina I, Gygi SP, Gladyshev VN, Hatfield DL.
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery.
Proc. Natl. Acad. Sci. U.S.A. 107: 21430-4, 2010.
3)  Yoo M, Carlson B, Tsuji P, Tobe R, Naranjo-Suarez S, Lee B, Davis C, Gladyshev V, Hatfield D.
Hatfield D, Berry M, Gladyshev V, eds.
Selenoproteins harboring a split personality in both preventing and promoting cancer. In: Selenium: Its molecular biology and role in human health. Volume 3.
New York: Springer Science+Business Media, LLC; 2012. p. 325-334 [Book Chapter]
4)  Carlson BA, Yoo M, Tobe R, Mueller C, Naranjo-Suarez S, Hoffmann VJ, Gladyshev VN, Hatfield DL.
Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis.
Carcinogenesis. [Epub ahead of print], 2012.
5)  Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL.
Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-a-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus.
PLoS ONE. 8: e71427, 2013.
6)  Kasaikina MV, Turanov AA, Avanesov A, Schweizer U, Seeher S, Bronson RT, Novoselov SN, Carlson BA, Hatfield DL, Gladyshev VN.
Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis.
Carcinogenesis. [Epub ahead of print], 2013.
7)  Patterson AD, Carlson BA, Li F, Bonzo JA, Yoo MH, Krausz KW, Conrad M, Chen C, Gonzalez FJ, Hatfield DL.
Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity.
Chem. Res. Toxicol. 2013.
8)  Tobe R, Naranjo-Suarez S, Everley RA, Carlson BA, Turanov AA, Tsuji PA, Yoo MH, Gygi SP, Gladyshev VN, Hatfield DL.
High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin.
J. Biol. Chem. 288: 14709-15, 2013.
9)  Naranjo-Suarez S, Carlson BA, Tobe R, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL.
Regulation of HIF-1a activity by overexpression of thioredoxin is independent of thioredoxin reductase status.
Mol. Cells. 36: 151-7, 2013.
10)  Moustafa ME, Carlson BA, Anver MR, Bobe G, Zhong N, Ward JM, Perella CM, Hoffmann VJ, Rogers K, Combs GF, Schweizer U, Merlino G, Gladyshev VN, Hatfield DL.
Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFa.
PLoS ONE. 8: e57389, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 11/18/2013.