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Our Science – Brechbiel Website

Martin W. Brechbiel, Ph.D.

Selected Publications

1)  Yong KJ, Milenic DE, Baidoo KE, Brechbiel MW.
212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint.
Br. J. Cancer. 108: 2013-20, 2013.
2)  Milenic DE, Baidoo KE, Shih JH, Wong KJ, Brechbiel MW.
Evaluation of platinum chemotherapy in combination with HER2-targeted a-particle radiation.
Cancer Biother. Radiopharm. 28: 441-9, 2013.
3)  Guérard F, Lee YS, Tripier R, Szajek LP, Deschamps JR, Brechbiel MW.
Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.
Chem. Commun. (Camb.). 49: 1002-4, 2013.
4)  Baidoo KE, Milenic DE, Brechbiel MW.
Methodology for labeling proteins and peptides with lead-212 (212Pb).
Nucl. Med. Biol. 40: 592-9, 2013.
5)  Burvenich IJ, Lee FT, Cartwright GA, O'Keefe GJ, Makris D, Cao D, Gong S, Chueh AC, Mariadason JM, Brechbiel MW, Beckman RA, Fujiwara K, von Roemeling R, Scott AM.
Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008.
Clin. Cancer Res. 19: 5984-93, 2013.
6)  Baidoo KE, Yong K, Brechbiel MW.
Molecular pathways: targeted a-particle radiation therapy.
Clin. Cancer Res. 19: 530-7, 2013.
7)  Nayak TK, Bernardo M, Milenic DE, Choyke PL, Brechbiel MW.
Orthotopic Pleural Mesothelioma in Mice: SPECT/CT and MR Imaging with HER1- and HER2-targeted Radiolabeled Antibodies.
Radiology. 267: 173-82, 2013.
8)  Kang CS, Song HA, Milenic DE, Baidoo KE, Brechbiel MW, Chong H.
Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using (212)Bi and (213)Bi: Radiolabeling, serum stability, and biodistribution and tumor uptake studies.
Nucl. Med. Biol. [Epub ahead of print], 2013.
9)  Guérard F, Gestin JF, Brechbiel MW.
Production of [(211)At]-astatinated radiopharmaceuticals and applications in targeted a-particle therapy.
Cancer Biother. Radiopharm. 28: 1-20, 2013.
10)  Yong KJ, Milenic DE, Baidoo KE, Brechbiel MW.
Sensitization of tumor to (212)pb radioimmunotherapy by gemcitabine involves initial abrogation of g2 arrest and blocked DNA damage repair by interference with rad51.
Int. J. Radiat. Oncol. Biol. Phys. 85: 1119-26, 2013.
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This page was last updated on 11/8/2013.