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Our Science – Brechbiel Website

Martin W. Brechbiel, Ph.D.

Selected Publications

1)  Guérard F, Lee Y, Brechbiel MW.
Rational Design, Synthesis, and Evaluation of Tetrahydroxamic Acid Chelators for Stable Complexation of Zirconium(IV).
Chemistry. [Epub ahead of print], 2014.
[Journal]
2)  Yong KJ, Milenic DE, Baidoo KE, Brechbiel MW.
212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint.
Br. J. Cancer. 108: 2013-20, 2013.
[Journal]
3)  Milenic DE, Baidoo KE, Shih JH, Wong KJ, Brechbiel MW.
Evaluation of platinum chemotherapy in combination with HER2-targeted a-particle radiation.
Cancer Biother. Radiopharm. 28: 441-9, 2013.
[Journal]
4)  Yong KJ, Milenic DE, Baidoo KE, Kim YS, Brechbiel MW.
Gene expression profiling upon (212) Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model.
Cancer Med. 2: 646-53, 2013.
[Journal]
5)  Guérard F, Lee YS, Tripier R, Szajek LP, Deschamps JR, Brechbiel MW.
Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.
Chem. Commun. (Camb.). 49: 1002-4, 2013.
[Journal]
6)  Baidoo KE, Milenic DE, Brechbiel MW.
Methodology for labeling proteins and peptides with lead-212 (212Pb).
Nucl. Med. Biol. 40: 592-9, 2013.
[Journal]
7)  Burvenich IJ, Lee FT, Cartwright GA, O'Keefe GJ, Makris D, Cao D, Gong S, Chueh AC, Mariadason JM, Brechbiel MW, Beckman RA, Fujiwara K, von Roemeling R, Scott AM.
Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008.
Clin. Cancer Res. 19: 5984-93, 2013.
[Journal]
8)  Baidoo KE, Yong K, Brechbiel MW.
Molecular pathways: targeted a-particle radiation therapy.
Clin. Cancer Res. 19: 530-7, 2013.
[Journal]
9)  Nayak TK, Bernardo M, Milenic DE, Choyke PL, Brechbiel MW.
Orthotopic Pleural Mesothelioma in Mice: SPECT/CT and MR Imaging with HER1- and HER2-targeted Radiolabeled Antibodies.
Radiology. 267: 173-82, 2013.
[Journal]
10)  Kang CS, Song HA, Milenic DE, Baidoo KE, Brechbiel MW, Chong H.
Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using (212)Bi and (213)Bi: Radiolabeling, serum stability, and biodistribution and tumor uptake studies.
Nucl. Med. Biol. 40: 600-5, 2013.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 4/23/2014.