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Our Science – Mitchell Website

James B. Mitchell, Ph.D.

Selected Publications

1)  Mitchell JB, Anver MR, Sowers A, Rosenberg PS, Figueroa M, Thetford A, Krishna MC, Albert PS, Cook JA.
The Antioxidant Tempol Reduces Carcinogenesis and Enhances Survival in Mice when Administered After Non-Lethal Total Body Radiation.
Cancer Res. 72: 4846-55, 2012.
2)  Davis RM, Sowers AL, Degraff W, Bernardo M, Thetford A, Krishna MC, Mitchell JB.
A novel nitroxide is an effective brain redox imaging contrast agent and in vivo radioprotector.
Free Radic. Biol. Med. 51: 780-90, 2011.
3)  Mitchell JB, Choudhuri R, Fabre K, Sowers AL, Citrin D, Zabludoff SD, Cook JA.
In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762.
Clin. Cancer Res. 16: 2076-84, 2010.
4)  Cotrim AP, Yoshikawa M, Sunshine AN, Zheng C, Sowers AL, Thetford AD, Cook JA, Mitchell JB, Baum BJ.
Pharmacological Protection from Radiation ± Cisplatin-induced Oral Mucositis.
Int. Radiat. Oncol. Biol. Phys. 83: 1284-90, 2012.
5)  Li F, Jiang C, Krausz KW, Li Y, Albert I, Hao H, Fabre KM, Mitchell JB, Patterson AD, Gonzalez FJ.
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity.
Nat Commun. 4: 2384, 2013.
6)  Dan T, Hewitt SM, Ohri N, Ly D, Soule BP, Smith SL, Matsuda K, Council C, Shankavaram U, Lippman ME, Mitchell JB, Camphausen K, Simone NL.
CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up.
Breast Cancer Res. Treat. 143: 11-8, 2014.
7)  Matsumoto S, Saito K, Takakusagi Y, Matsuo M, Munasinghe JP, Morris HD, Lizak MJ, Merkle H, Yasukawa K, Devasahayam N, Suburamanian S, Mitchell JB, Krishna MC.
In Vivo Imaging of Tumor Physiological, Metabolic, and Redox Changes in Response to the Anti-Angiogenic Agent Sunitinib: Longitudinal Assessment to Identify Transient Vascular Renormalization.
Antioxid. Redox Signal. [Epub ahead of print], 2014.
8)  Salem GH, Dennis JU, Krynitsky J, Garmendia-Cedillos M, Swaroop K, Malley JD, Pajevic S, Abuhatzira L, Bustin M, Gillet J, Gottesman MM, Mitchell JB, Pohida TJ.
SCORHE: A novel and practical approach to video monitoring of laboratory mice housed in vivarium cage racks.
Behav Res Methods. [Epub ahead of print], 2014.
9)  Liu Y, Shim E, Nguyen P, Gibbons AT, Mitchell JB, Poirier MC.
Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.
Toxicol. Sci. 139: 133-41, 2014.
10)  Saleh AD, Simone BA, Palazzo J, Savage JE, Sano Y, Dan T, Jin L, Champ CE, Zhao S, Lim M, Sotgia F, Camphausen K, Pestell RG, Mitchell JB, Lisanti MP, Simone NL.
Caloric restriction augments radiation efficacy in breast cancer.
Cell Cycle. 12: 1955-63, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 6/30/2014.