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Our Science – Mitchell Website

James B. Mitchell, Ph.D.

Selected Publications

1)  Saleh AD, Simone BA, Palazzo J, Savage JE, Sano Y, Dan T, Jin L, Champ CE, Zhao S, Lim M, Sotgia F, Camphausen K, Pestell RG, Mitchell JB, Lisanti MP, Simone NL.
Caloric restriction augments radiation efficacy in breast cancer.
Cell Cycle. 12: 1955-63, 2013.
2)  Friedman JA, Wise SC, Hu M, Gouveia C, Vander Broek R, Freudlsperger C, Kannabiran VR, Arun P, Mitchell JB, Chen Z, Van Waes C.
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Transl Oncol. 6: 429-41, 2013.
3)  Li F, Patterson AD, Krausz KW, Jiang C, Bi H, Sowers AL, Cook JA, Mitchell JB, Gonzalez FJ.
Metabolomics reveals that tumor xenografts induce liver dysfunction.
Mol. Cell Proteomics. 12: 2126-35, 2013.
4)  Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C.
PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer.
Clin. Cancer Res. 19: 3808-19, 2013.
5)  Matsumoto S, Saito K, Yasui H, Morris HD, Munasinghe JP, Lizak M, Merkle H, Ardenkjaer-Larsen JH, Choudhuri R, Devasahayam N, Subramanian S, Koretsky AP, Mitchell JB, Krishna MC.
EPR oxygen imaging and hyperpolarized (13) C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Magn Reson Med. 69: 1443-1450, 2013.
6)  Horton JA, Chung EJ, Hudak KE, Sowers A, Thetford A, White AO, Mitchell JB, Citrin DE.
Inhibition of radiation-induced skin fibrosis with imatinib.
Int. J. Radiat. Biol. 89: 162-70, 2013.
7)  Han G, Bian L, Li F, Cotrim A, Wang D, Lu J, Deng Y, Bird G, Sowers A, Mitchell JB, Gutkind JS, Zhao R, Raben D, Ten Dijke P, Refaeli Y, Zhang Q, Wang XJ.
Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis.
Nat. Med. 19: 421-8, 2013.
8)  Li F, Pang X, Krausz KW, Jiang C, Chen C, Cook JA, Krishna MC, Mitchell JB, Gonzalez FJ, Patterson AD.
Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.
J. Proteome Res. 12: 1369-76, 2013.
9)  Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG.
Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.
Proc. Natl. Acad. Sci. U.S.A. 109: 19403-7, 2012.
10)  Subramanian S, Devasahayam N, Matsumoto S, Saito K, Mitchell JB, Krishna MC.
Echo-based Single Point Imaging (ESPI): A novel pulsed EPR imaging modality for high spatial resolution and quantitative oximetry.
J. Magn. Reson. 218: 105-14, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 8/30/2013.