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Our Science – Pathak Website

Vinay K. Pathak, Ph.D.

Selected Publications

1)  Burdick R, Hu W, Pathak V.
Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.
Proc Natl Acad Sci USA Plus. 110: E4780-9, 2013.
2)  Paprotka T, Delviks-Frankenberry K, Cingoz O, Martinez A, Kung H, Tepper C, Hu W, Fivash M, Coffin J, Pathak V.
Recombinant origin of the retrovirus XMRV.
Science. 333: 97-101, 2011.
Full Text Article. [Journal]
3)  Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK.
HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision.
Proc. Natl. Acad. Sci. U.S.A. 105: 10943-10948, 2008.
4)  Nikolenko GN, Palmer S, Maldarelli F, Mellors JW, Coffin JM, Pathak VK.
Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision.
Proc Natl Acad Sci U S A. 102: 2093-8, 2005.
5)  Xu H, Svarovskaia ES, Barr R, Zhang Y, Khan MA, Strebel K, Pathak VK.
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion.
Proc Natl Acad Sci U S A. 101: 5652-7, 2004.
6)  Smith JL, Izumi T, Borbet TC, Hagedorn AN, Pathak VK.
HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants.
J Virol. 2014.
In Press. [Journal]
7)  Desimmie BA, Delviks-Frankenberrry KA, Burdick RC, Qi D, Izumi T, Pathak VK.
Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them All.
J. Mol. Biol. 426: 1220-1245, 2014.
8)  Chaipan C, Smith JL, Hu WS, Pathak VK.
APOBEC3G Restricts HIV-1 to a Greater Extent than APOBEC3F and APOBEC3DE in Human Primary CD4+ T Cells and Macrophages.
J. Virol. 87: 444-53, 2013.
9)  Delviks-Frankenberry KA, Lengruber RB, Santos AF, Silveira JM, Soares MA, Kearney MF, Maldarelli F, Pathak VK.
Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance.
Virology. 435: 433-41, 2013.
10)  Nikolaitchik O, Dilley K, Fu W, Gorelick R, Tai S, Soheilian F, Ptak R, Nagashima K, Pathak V, Hu W.
Dimeric RNA recognition regulates HIV-1 genome packaging.
PLoS Pathog. 9(3): e1003249: e1003249, 2013.
Full Text Article. [Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 8/13/2014.