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Our Science – Byrd Website

R. Andrew Byrd, Ph.D.

Selected Publications

1)  Das R, Mariano J, Tsai YC, Kalathur RC, Kostova Z, Li J, Tarasov SG, McFeeters RL, Altieri AS, Ji X, Byrd RA, Weissman AM.
Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Mol. Cell. 34: 674-85, 2009.
2)  Das R, Liang YH, Mariano J, Li J, Huang T, King A, Tarasov SG, Weissman AM, Ji X, Byrd RA.
Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
EMBO J. 32: 2504-16, 2013.
3)  Cecchi F, Pajalunga D, Fowler CA, Uren A, Rabe DC, Peruzzi B, Macdonald NJ, Blackman DK, Stahl SJ, Byrd RA, Bottaro DP.
Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling.
Cancer Cell. 22: 250-62, 2012.
4)  Gaponenko V, Sarma SP, Altieri AS, Horita DA, Li J, Byrd RA.
Improving the accuracy of NMR structures of large proteins using pseudocontact shifts as long-range restraints.
J. Biomol. NMR. 28: 205-12, 2004.
5)  Zwahlen C, Gardner KH, Sarma SP, Horita DA, Byrd RA, Kay LE.
An NMR experiment for measuring methyl-methyl NOEs in 13C-labeled proteins with high resolution.
J. Am. Chem. Soc. 120: 7617-25, 1998.
6)  Huang T, Li J, Byrd RA.
Solution structure of lysine-free (K0) ubiquitin.
Protein Sci. 23: 662-7, 2014.
7)  Gruschus JM, Byrd RA, Randazzo PA.
The importance of seeing surface (effects).
Structure. 22: 363-5, 2014.
8)  Metzger MB, Liang YH, Das R, Mariano J, Li S, Li J, Kostova Z, Byrd RA, Ji X, Weissman AM.
A structurally unique E2-binding domain activates ubiquitination by the ERAD E2, Ubc7p, through multiple mechanisms.
Mol. Cell. 50: 516-27, 2013.
9)  Fang X, Wang J, O'Carroll IP, Mitchell M, Zuo X, Wang Y, Yu P, Liu Y, Rausch JW, Dyba MA, Kjems J, Schwieters CD, Seifert S, Winans RE, Watts NR, Stahl SJ, Wingfield PT, Byrd RA, Le Grice SF, Rein A, Wang YX.
An Unusual Topological Structure of the HIV-1 Rev Response Element.
Cell. 155: 594-605, 2013.
10)  Byrd RA, Weissman AM.
Compact Parkin only: insights into the structure of an autoinhibited ubiquitin ligase.
EMBO J. 32: 2087-9, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 6/17/2014.