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Our Science – Ashwell Website

Jonathan D. Ashwell, M.D.

Selected Publications

1)  Salvador JM, Mittelstadt PR, Guszczynski T, Copeland TD, Yamaguchi H, Appella E, Fornace AJ, Ashwell JD.
Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases.
Nat Immunol. 6: 390-5, 2005.
2)  Jirmanova L, Giardino Torchia ML, Sarma ND, Mittelstadt PR, Ashwell JD.
Lack of the T-cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.
Blood. 118: 3280-9, 2011.
3)  Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD.
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.
Science. 288: 874-7, 2000.
4)  Conze DB, Zhao Y, Ashwell JD.
Non-canonical NF-kappaB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.
PLoS Biol. 8: e1000518, 2010.
5)  Mittelstadt PR, Monteiro JP, Ashwell JD.
Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness.
J. Clin. Invest. 122: 2384-94, 2012.
6)  Kuka M, Ashwell JD.
A method for high purity sorting of rare cell subsets applied to TDC.
J. Immunol. Methods. 2013.
7)  Giardino Torchia ML, Conze DB, Jankovic D, Ashwell JD.
Balance between NF-?B p100 and p52 regulates T cell costimulation dependence.
J. Immunol. 190: 549-55, 2013.
8)  Giardino Torchia ML, Conze DB, Ashwell JD.
c-IAP1 and c-IAP2 redundancy differs between T and B cells.
PLoS ONE. 8: e66161, 2013.
9)  Kugler DG, Mittelstadt PR, Ashwell JD, Sher A, Jankovic D.
CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection.
J. Exp. Med. 210: 1919-27, 2013.
10)  Munitic I, Kuka M, Allam A, Scoville JP, Ashwell JD.
CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus.
J. Immunol. 190: 1169-79, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 11/12/2013.