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Our Science – Ashwell Website

Jonathan D. Ashwell, M.D.

Selected Publications

1)  Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD.
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.
Science. 288: 874-7, 2000.
2)  Salvador JM, Mittelstadt PR, Guszczynski T, Copeland TD, Yamaguchi H, Appella E, Fornace AJ, Ashwell JD.
Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases.
Nat Immunol. 6: 390-5, 2005.
3)  Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD.
NEMO is a sensor of Lys 63-linked polyubiquitination and functions in NF-kappaB activation.
Nat. Cell Biol. 8: 398-406, 2006.
4)  Mittelstadt PR, Monteiro JP, Ashwell JD.
Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness.
J. Clin. Invest. 122: 2384-94, 2012.
5)  Alam MS, Gaida MM, Ogawa Y, Kolios AG, Lasitschka F, Ashwell JD.
Counter-regulation of T cell effector function by differentially activated p38.
J. Exp. Med. 211: 1257-70, 2014.
6)  Allam A, Swiecki M, Vermi W, Ashwell JD, Colonna M.
Dual Function of CD70 in Viral Infection: Modulator of Early Cytokine Responses and Activator of Adaptive Responses.
J. Immunol. 2014.
7)  Presman DM, Ogara MF, Stortz M, Alvarez LD, Pooley JR, Schiltz RL, Grøntved L, Johnson TA, Mittelstadt PR, Ashwell JD, Ganesan S, Burton G, Levi V, Hager GL, Pecci A.
Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.
PLoS Biol. 12: e1001813, 2014.
8)  Guo L, Zheng Z, Ai J, Howatt DA, Mittelstadt PR, Thacker S, Daugherty A, Ashwell JD, Remaley AT, Li XA.
Scavenger Receptor BI and High-Density Lipoprotein Regulate Thymocyte Apoptosis in Sepsis.
Arterioscler. Thromb. Vasc. Biol. 34: 966-75, 2014.
9)  Kuka M, Ashwell JD.
A method for high purity sorting of rare cell subsets applied to TDC.
J. Immunol. Methods. 2013.
10)  Giardino Torchia ML, Conze DB, Jankovic D, Ashwell JD.
Balance between NF-?B p100 and p52 regulates T cell costimulation dependence.
J. Immunol. 190: 549-55, 2013.
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This page was last updated on 6/16/2014.