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Our Science – Young Website

Matthew R. Young, Ph.D.

Selected Publications

1)  Li W, Hua B, Saud SM, Lin H, Hou W, Matter MS, Jia L, Colburn NH, Young MR.
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Mol. Carcinog. [Epub ahead of print], 2014.
2)  Saud SM, Young MR, Jones-Hall YL, Ileva L, Evbuomwan MO, Wise J, Colburn NH, Kim YS, Bobe G.
Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and ß-catenin.
Cancer Res. 73: 5473-84, 2013.
3)  Mitsunaga M, Kosaka N, Choyke PL, Young MR, Dextras CR, Saud SM, Colburn NH, Sakabe M, Nagano T, Asanuma D, Urano Y, Kobayashi H.
Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe.
Gut. 62: 1179-86, 2013.
4)  Young MR, Ileva LV, Bernardo M, Riffle LA, Jones YL, Kim YS, Colburn NH, Choyke PL.
Monitoring of tumor promotion and progression in a mouse model of inflammation-induced colon cancer with magnetic resonance colonography.
Neoplasia. 11: 237-46, 2009.
5)  Urano Y, Sakabe M, Kosaka N, Ogawa M, Mitsunaga M, Asanuma D, Kamiya M, Young MR, Nagano T, Choyke PL, Kobayashi H.
Rapid cancer detection by topically spraying a ?-glutamyltranspeptidase-activated fluorescent probe.
Sci Transl Med. 3: 110ra119, 2011.
6)  Wu L, Jiang H, Chawsheen HA, Mishra M, Young MR, Gerard M, Toledano MB, Colburn NH, Wei Q.
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Carcinogenesis. [Epub ahead of print], 2014.
7)  Hwang S, Baker AR, Young MR, Colburn NH.
Tumor suppressor PDCD4 inhibits NF-?B-dependent transcription in human glioblastoma cells by direct interaction with p65.
Carcinogenesis. [Epub ahead of print], 2014.
8)  Sun L, Mathews LA, Cabarcas SM, Zhang X, Yang A, Zhang Y, Young MR, Klarmann KD, Keller JR, Farrar WL.
Epigenetic Regulation of SOX9 by the NF-?B Signaling Pathway in Pancreatic Cancer Stem Cells.
Stem Cells. 31: 1454-66, 2013.
9)  Wei Q, Jiang H, Baker A, Dodge LK, Gerard M, Young MR, Toledano MB, Colburn NH.
Loss of sulfiredoxin renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis.
Carcinogenesis. 34: 1403-10, 2013.
10)  Camalier CE, Yi M, Yu LR, Hood BL, Conrads KA, Lee YJ, Lin Y, Garneys LM, Bouloux GF, Young MR, Veenstra TD, Stephens RM, Colburn NH, Conrads TP, Beck GR.
An integrated understanding of the physiological response to elevated extracellular phosphate.
J. Cell. Physiol. 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 7/14/2014.