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Our Science – Meier Website

Jordan L. Meier, Ph.D.

Selected Publications

1)  Meier JL.
Metabolic Mechanisms of Epigenetic Regulation.
ACS Chem. Biol. 8: 2607-2621, 2013.
[Journal]
2)  Kang JS, Meier JL, Dervan PB.
Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition.
J. Am. Chem. Soc. 136: 3687-94, 2014.
[Journal]
3)  Yang F, Nickols NG, Li BC, Szablowski JO, Hamilton SR, Meier JL, Wang CM, Dervan PB.
Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit.
J. Med. Chem. 56: 7449-57, 2013.
[Journal]
4)  Edwards JS, Betts L, Frazier ML, Pollet RM, Kwong SM, Walton WG, Ballentine WK, Huang JJ, Habibi S, Del Campo M, Meier JL, Dervan PB, Firth N, Redinbo MR.
Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.
Proc. Natl. Acad. Sci. U.S.A. 110: 2804-9, 2013.
[Journal]
5)  Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB.
Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing.
J. Am. Chem. Soc. 134: 17814-22, 2012.
[Journal]
6)  Chenoweth DM, Meier JL, Dervan PB.
Pyrrole-Imidazole Polyamides Distinguish Between Double-Helical DNA and RNA.
Angew. Chem. Int. Ed. Engl. 2012.
[Journal]
7)  Hargrove AE, Raskatov JA, Meier JL, Montgomery DC, Dervan PB.
Characterization and solubilization of pyrrole-imidazole polyamide aggregates.
J. Med. Chem. 55: 5425-32, 2012.
[Journal]
8)  Meier JL, Montgomery DC, Dervan PB.
Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.
Nucleic Acids Res. 40: 2345-56, 2012.
[Journal]
9)  Raskatov JA, Meier JL, Puckett JW, Yang F, Ramakrishnan P, Dervan PB.
Modulation of NF-kappa-B-dependent gene transcription using programmable DNA minor groove binders.
Proc. Natl. Acad. Sci. U.S.A. 109: 1023-8, 2012.
[Journal]
10)  van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E.
The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.
Chem. Biol. 19: 559-71, 2012.
[Journal]
11)  Muzikar KA, Meier JL, Gubler DA, Raskatov JA, Dervan PB.
Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.
Org. Lett. 13: 5612-5, 2011.
[Journal]
12)  Meier JL, Patel AD, Niessen S, Meehan M, Kersten R, Yang JY, Rothmann M, Cravatt BF, Dorrestein PC, Burkart MD, Bafna V.
Practical 4"-phosphopantetheine active site discovery from proteomic samples.
J. Proteome Res. 10: 320-9, 2011.
[Journal]
13)  Meier JL, Burkart MD.
Proteomic analysis of polyketide and nonribosomal peptide biosynthesis.
Curr Opin Chem Biol. 15: 48-56, 2011.
[Journal]
14)  Meier JL, Haushalter RW, Burkart MD.
A mechanism based protein crosslinker for acyl carrier protein dehydratases.
Bioorg. Med. Chem. Lett. 20: 4936-9, 2010.
[Journal]
15)  Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, Burkart MD.
An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis.
ACS Chem. Biol. 4: 948-57, 2009.
[Journal]
16)  Meier JL, Burkart MD.
Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes.
Meth. Enzymol. 458: 219-54, 2009.
[Journal]
17)  Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, Burkart MD.
Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis.
Chem. Biol. 16: 372-81, 2009.
[Journal]
18)  Mercer AC, Meier JL, Torpey JW, Burkart MD.
In vivo modification of native carrier protein domains.
Chembiochem. 10: 1091-100, 2009.
[Journal]
19)  Meier JL, Burkart MD.
The chemical biology of modular biosynthetic enzymes.
Chem Soc Rev. 38: 2012-45, 2009.
[Journal]
20)  Mercer AC, Meier JL, Hur GH, Smith AR, Burkart MD.
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli.
Bioorg. Med. Chem. Lett. 18: 5991-4, 2008.
[Journal]
21)  Meier JL, Mercer AC, Burkart MD.
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.
J. Am. Chem. Soc. 130: 5443-5, 2008.
[Journal]
22)  Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD.
Probing the compatibility of type II ketosynthase-carrier protein partners.
Chembiochem. 9: 2096-103, 2008.
[Journal]
23)  Meier JL, Barrows-Yano T, Foley TL, Wike CL, Burkart MD.
The unusual macrocycle forming thioesterase of mycolactone.
Mol Biosyst. 4: 663-71, 2008.
[Journal]
24)  Meier JL, Mercer AC, Rivera H, Burkart MD.
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.
J. Am. Chem. Soc. 128: 12174-84, 2006.
[Journal]
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This page was last updated on 3/10/2014.