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Our Science – Meier Website

Jordan L. Meier, Ph.D.

Selected Publications

1)  Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB.
Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing.
J. Am. Chem. Soc. 134: 17814-22, 2012.
[Journal]
2)  Chenoweth DM, Meier JL, Dervan PB.
Pyrrole-Imidazole Polyamides Distinguish Between Double-Helical DNA and RNA.
Angew. Chem. Int. Ed. Engl. 2012.
[Journal]
3)  Hargrove AE, Raskatov JA, Meier JL, Montgomery DC, Dervan PB.
Characterization and solubilization of pyrrole-imidazole polyamide aggregates.
J. Med. Chem. 55: 5425-32, 2012.
[Journal]
4)  Meier JL, Montgomery DC, Dervan PB.
Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.
Nucleic Acids Res. 40: 2345-56, 2012.
[Journal]
5)  Raskatov JA, Meier JL, Puckett JW, Yang F, Ramakrishnan P, Dervan PB.
Modulation of NF-kappa-B-dependent gene transcription using programmable DNA minor groove binders.
Proc. Natl. Acad. Sci. U.S.A. 109: 1023-8, 2012.
[Journal]
6)  van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E.
The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.
Chem. Biol. 19: 559-71, 2012.
[Journal]
7)  Muzikar KA, Meier JL, Gubler DA, Raskatov JA, Dervan PB.
Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.
Org. Lett. 13: 5612-5, 2011.
[Journal]
8)  Meier JL, Patel AD, Niessen S, Meehan M, Kersten R, Yang JY, Rothmann M, Cravatt BF, Dorrestein PC, Burkart MD, Bafna V.
Practical 4"-phosphopantetheine active site discovery from proteomic samples.
J. Proteome Res. 10: 320-9, 2011.
[Journal]
9)  Meier JL, Burkart MD.
Proteomic analysis of polyketide and nonribosomal peptide biosynthesis.
Curr Opin Chem Biol. 15: 48-56, 2011.
[Journal]
10)  Meier JL, Haushalter RW, Burkart MD.
A mechanism based protein crosslinker for acyl carrier protein dehydratases.
Bioorg. Med. Chem. Lett. 20: 4936-9, 2010.
[Journal]
11)  Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, Burkart MD.
An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis.
ACS Chem. Biol. 4: 948-57, 2009.
[Journal]
12)  Meier JL, Burkart MD.
Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes.
Meth. Enzymol. 458: 219-54, 2009.
[Journal]
13)  Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, Burkart MD.
Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis.
Chem. Biol. 16: 372-81, 2009.
[Journal]
14)  Mercer AC, Meier JL, Torpey JW, Burkart MD.
In vivo modification of native carrier protein domains.
Chembiochem. 10: 1091-100, 2009.
[Journal]
15)  Meier JL, Burkart MD.
The chemical biology of modular biosynthetic enzymes.
Chem Soc Rev. 38: 2012-45, 2009.
[Journal]
16)  Mercer AC, Meier JL, Hur GH, Smith AR, Burkart MD.
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli.
Bioorg. Med. Chem. Lett. 18: 5991-4, 2008.
[Journal]
17)  Meier JL, Mercer AC, Burkart MD.
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.
J. Am. Chem. Soc. 130: 5443-5, 2008.
[Journal]
18)  Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD.
Probing the compatibility of type II ketosynthase-carrier protein partners.
Chembiochem. 9: 2096-103, 2008.
[Journal]
19)  Meier JL, Barrows-Yano T, Foley TL, Wike CL, Burkart MD.
The unusual macrocycle forming thioesterase of mycolactone.
Mol Biosyst. 4: 663-71, 2008.
[Journal]
20)  Meier JL, Mercer AC, Rivera H, Burkart MD.
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.
J. Am. Chem. Soc. 128: 12174-84, 2006.
[Journal]
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This page was last updated on 11/14/2012.