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Our Science – Jones Website

Jennifer Clare Jones, M.D., Ph.D.

Selected Publications

1)  Parker JJ, Jones JC, Strober S, Knox SJ.
Characterization of direct radiation-induced immune function and molecular signaling changes in an antigen presenting cell line.
Clin. Immunol. 148: 44-55, 2013.
2)  Jones JC, Freeman GJ.
Costimulatory genes: hotspots of conflict between host defense and autoimmunity.
Immunity. 38: 1083-5, 2013.
3)  Fasola CE, Jones JC, Huang DD, Le QT, Hoppe RT, Donaldson SS.
Low-dose radiation therapy (2 gy × 2) in the treatment of orbital lymphoma.
Int. J. Radiat. Oncol. Biol. Phys. 86: 930-5, 2013.
4)  Hiniker SM, Chen DS, Reddy S, Chang DT, Jones JC, Mollick JA, Swetter SM, Knox SJ.
A systemic complete response of metastatic melanoma to local radiation and immunotherapy.
Transl Oncol. 5: 404-7, 2012.
5)  Yao Z, Jones J, Kohrt H, Strober S.
Selective resistance of CD44hi T cells to p53-dependent cell death results in persistence of immunologic memory after total body irradiation.
J. Immunol. 187: 4100-8, 2011.
6)  Lee HH, Meyer EH, Goya S, Pichavant M, Kim HY, Bu X, Umetsu SE, Jones JC, Savage PB, Iwakura Y, Casasnovas JM, Kaplan G, Freeman GJ, DeKruyff RH, Umetsu DT.
Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity.
J. Immunol. 185: 5225-35, 2010.
7)  Yao Z, Liu Y, Jones J, Strober S.
Differences in Bcl-2 expression by T-cell subsets alter their balance after in vivo irradiation to favor CD4+Bcl-2hi NKT cells.
Eur. J. Immunol. 39: 763-75, 2009.
8)  Bouley DM, McIntire JJ, Harris BT, Tolwani RJ, Otto GM, DeKruyff RH, Hayflick SJ.
Spontaneous murine neuroaxonal dystrophy: a model of infantile neuroaxonal dystrophy.
J. Comp. Pathol. 134: 161-70, 2005.
9)  Umetsu SE, Lee WL, McIntire JJ, Downey L, Sanjanwala B, Akbari O, Berry GJ, Nagumo H, Freeman GJ, Umetsu DT, DeKruyff RH.
TIM-1 induces T cell activation and inhibits the development of peripheral tolerance.
Nat. Immunol. 6: 447-54, 2005.
10)  Umetsu DT, McIntire JJ, DeKruyff RH.
TIM-1, hepatitis A virus and the hygiene theory of atopy: association of TIM-1 with atopy.
J. Pediatr. Gastroenterol. Nutr. 40 Suppl 1: S43, 2005.
11)  TePas EC, Hoyte EG, McIntire JJ, Umetsu DT.
Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals.
Ann. Allergy Asthma Immunol. 92: 25-31, 2004.
12)  McIntire JJ, Umetsu DT, DeKruyff RH.
TIM-1, a novel allergy and asthma susceptibility gene.
Springer Semin. Immunopathol. 25: 335-48, 2004.
13)  McIntire JJ, Umetsu SE, Macaubas C, Hoyte EG, Cinnioglu C, Cavalli-Sforza LL, Barsh GS, Hallmayer JF, Underhill PA, Risch NJ, Freeman GJ, DeKruyff RH, Umetsu DT.
Immunology: hepatitis A virus link to atopic disease.
Nature. 425: 576, 2003.
14)  Umetsu DT, McIntire JJ, Akbari O, Macaubas C, DeKruyff RH.
Asthma: an epidemic of dysregulated immunity.
Nat. Immunol. 3: 715-20, 2002.
15)  Walter DM, McIntire JJ, Berry G, McKenzie AN, Donaldson DD, DeKruyff RH, Umetsu DT.
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity.
J. Immunol. 167: 4668-75, 2001.
16)  McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, Freeman GJ, Umetsu DT, DeKruyff RH.
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.
Nat. Immunol. 2: 1109-16, 2001.
17)  Hansen G, McIntire JJ, Yeung VP, Berry G, Thorbecke GJ, Chen L, DeKruyff RH, Umetsu DT.
CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation.
J. Clin. Invest. 105: 61-70, 2000.
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This page was last updated on 5/2/2014.