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Our Science – Lazarevic Website

Vanja Lazarevic, Ph.D.

Selected Publications

1)  Hong C, Luckey MA, Ligons DL, Waickman AT, Park JY, Kim GY, Keller HR, Etzensperger R, Tai X, Lazarevic V, Feigenbaum L, Catalfamo M, Walsh ST, Park JH.
Activated T Cells Secrete an Alternatively Spliced Form of Common ?-Chain that Inhibits Cytokine Signaling and Exacerbates Inflammation.
Immunity. 40: 910-23, 2014.
2)  Wang Y, Godec J, Ben-Aissa K, Cui K, Zhao K, Pucsek AB, Lee YK, Weaver CT, Yagi R, Lazarevic V.
The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-?-Producing T Helper 17 Cells.
Immunity. 40: 355-66, 2014.
3)  Lazarevic V, Glimcher LH, Lord GM.
T-bet: a bridge between innate and adaptive immunity.
Nat. Rev. Immunol. 13: 777-89, 2013.
4)  Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH.
Control of bone resorption in mice by Schnurri-3.
Proc. Natl. Acad. Sci. U.S.A. 109: 8173-8, 2012.
5)  Staton TL, Lazarevic V, Jones DC, Lanser AJ, Takagi T, Ishii S, Glimcher LH.
Dampening of death pathways by schnurri-2 is essential for T-cell development.
Nature. 472: 105-9, 2011.
6)  Lazarevic V, Glimcher LH.
T-bet in disease.
Nat. Immunol. 12: 597-606, 2011.
7)  Lazarevic V, Chen X, Shim J, Hwang E, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH.
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORgammat.
Nat. Immunol. 12: 96-104, 2011.
8)  Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M.
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections.
J. Immunol. 184: 1710-20, 2010.
9)  Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH.
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells.
Nat. Immunol. 10: 306-13, 2009.
10)  Lazarevic V, Martinon F.
Linking inflammasome activation and phagosome maturation.
Cell Host Microbe. 3: 199-200, 2008.
11)  Deslouches B, Phadke SM, Lazarevic V, Cascio M, Islam K, Montelaro RC, Mietzner TA.
De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity.
Antimicrob. Agents Chemother. 49: 316-22, 2005.
12)  Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I.
Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production.
J. Immunol. 175: 4593-602, 2005.
13)  Lazarevic V, Yankura DJ, DiVito SJ, Flynn JL.
Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice.
Infect. Immun. 73: 2910-22, 2005.
14)  Lazarevic V, Nolt D, Flynn JL.
Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses.
J. Immunol. 175: 1107-17, 2005.
15)  Lazarevic V, Myers AJ, Scanga CA, Flynn JL.
CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection.
Immunity. 19: 823-35, 2003.
16)  Lazarevic V, Flynn J.
CD8+ T cells in tuberculosis.
Am. J. Respir. Crit. Care Med. 166: 1116-21, 2002.
17)  Phadke SM, Lazarevic V, Bahr CC, Islam K, Stolz DB, Watkins S, Tencza SB, Vogel HJ, Montelaro RC, Mietzner TA.
Lentivirus lytic peptide 1 perturbs both outer and inner membranes of Serratia marcescens.
Antimicrob. Agents Chemother. 46: 2041-5, 2002.
18)  Serbina NV, Lazarevic V, Flynn JL.
CD4(+) T cells are required for the development of cytotoxic CD8(+) T cells during Mycobacterium tuberculosis infection.
J. Immunol. 167: 6991-7000, 2001.
Click Here to View Collapsed Bibliography.

This page was last updated on 7/9/2014.