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Our Science – Lazarevic Website

Vanja Lazarevic, Ph.D.

Selected Publications

1)  Wang Y, Godec J, Ben-Aissa K, Cui K, Zhao K, Pucsek AB, Lee YK, Weaver CT, Yagi R, Lazarevic V.
The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-?-Producing T Helper 17 Cells.
Immunity. 40: 355-66, 2014.
2)  Lazarevic V, Glimcher LH, Lord GM.
T-bet: a bridge between innate and adaptive immunity.
Nat. Rev. Immunol. 13: 777-89, 2013.
3)  Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH.
Control of bone resorption in mice by Schnurri-3.
Proc. Natl. Acad. Sci. U.S.A. 109: 8173-8, 2012.
4)  Staton TL, Lazarevic V, Jones DC, Lanser AJ, Takagi T, Ishii S, Glimcher LH.
Dampening of death pathways by schnurri-2 is essential for T-cell development.
Nature. 472: 105-9, 2011.
5)  Lazarevic V, Glimcher LH.
T-bet in disease.
Nat. Immunol. 12: 597-606, 2011.
6)  Lazarevic V, Chen X, Shim J, Hwang E, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH.
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORgammat.
Nat. Immunol. 12: 96-104, 2011.
7)  Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M.
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections.
J. Immunol. 184: 1710-20, 2010.
8)  Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH.
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells.
Nat. Immunol. 10: 306-13, 2009.
9)  Lazarevic V, Martinon F.
Linking inflammasome activation and phagosome maturation.
Cell Host Microbe. 3: 199-200, 2008.
10)  Deslouches B, Phadke SM, Lazarevic V, Cascio M, Islam K, Montelaro RC, Mietzner TA.
De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity.
Antimicrob. Agents Chemother. 49: 316-22, 2005.
11)  Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I.
Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production.
J. Immunol. 175: 4593-602, 2005.
12)  Lazarevic V, Yankura DJ, DiVito SJ, Flynn JL.
Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice.
Infect. Immun. 73: 2910-22, 2005.
13)  Lazarevic V, Nolt D, Flynn JL.
Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses.
J. Immunol. 175: 1107-17, 2005.
14)  Lazarevic V, Myers AJ, Scanga CA, Flynn JL.
CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection.
Immunity. 19: 823-35, 2003.
15)  Lazarevic V, Flynn J.
CD8+ T cells in tuberculosis.
Am. J. Respir. Crit. Care Med. 166: 1116-21, 2002.
16)  Phadke SM, Lazarevic V, Bahr CC, Islam K, Stolz DB, Watkins S, Tencza SB, Vogel HJ, Montelaro RC, Mietzner TA.
Lentivirus lytic peptide 1 perturbs both outer and inner membranes of Serratia marcescens.
Antimicrob. Agents Chemother. 46: 2041-5, 2002.
17)  Serbina NV, Lazarevic V, Flynn JL.
CD4(+) T cells are required for the development of cytotoxic CD8(+) T cells during Mycobacterium tuberculosis infection.
J. Immunol. 167: 6991-7000, 2001.
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This page was last updated on 4/1/2014.