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Our Science – Schneekloth Website

John 'Jay' Schneekloth Jr., Ph.D.

Selected Publications

1)  Sztuba-Solinska J, Shenoy SR, Gareiss P, Krumpe LR, Le Grice SF, O'Keefe BR, Schneekloth JS.
Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays.
J. Am. Chem. Soc. 2014.
2)  Kim YS, Keyser SG, Schneekloth JS.
Synthesis of 2',3',4'-trihydroxyflavone (2-D08), an inhibitor of protein sumoylation.
Bioorg. Med. Chem. Lett. 24: 1094-7, 2014.
3)  Kim YS, Nagy K, Keyser S, Schneekloth JS.
An electrophoretic mobility shift assay identifies a mechanistically unique inhibitor of protein sumoylation.
Chem. Biol. 20: 604-13, 2013.
4)  Kim J, Schneekloth JS, Sorensen EJ.
A chemical synthesis of 11-methoxy mitragynine pseudoindoxyl featuring the interrupted Ugi reaction.
Chem Sci. 3: 2849-2852, 2012.
5)  Noblin DJ, Page CM, Tae HS, Gareiss PC, Schneekloth JS, Crews CM.
A HaloTag-based Small Molecule Microarray Screening Methodology with Increased Sensitivity and Multiplex Capabilities.
ACS Chem. Biol. 7: 2055-63, 2012.
6)  Schneekloth JS, Crews CM.
Natural Product Inhibitors of the Ubiquitin-Proteasome Pathway.
Curr. Drug Targets. 12: 1581-94, 2011.
7)  Schneekloth JS, Kim J, Sorensen EJ.
An interrupted Ugi reaction enables the preparation of substituted indoxyls and aminoindoles.
Tetrahedron. 65: 3096-3101, 2009.
8)  Petri AF, Schneekloth JS, Mandal AK, Crews CM.
Synthesis of the C3-C18 fragment of amphidinolides G and H.
Org. Lett. 9: 3001-4, 2007.
9)  Schneekloth, Jr. JS, Pucheault M, Crews CM.
Construction of Highly Substituted Stereodefined Dienes by Cross-Coupling of alpha-Allenic Acetates.
European J. Org. Chem. 1: 40-43, 2007.
10)  Schneekloth JS, Sanders JL, Hines J, Crews CM.
Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog.
Bioorg. Med. Chem. Lett. 16: 3855-8, 2006.
Click Here to View Expanded Bibliography.

This page was last updated on 5/30/2014.