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Our Science – Tofilon Website

Philip Tofilon, Ph.D.

Selected Publications

1)  Lü X, de la Peña L, Barker C, Camphausen K, Tofilon PJ.
Radiation-induced changes in gene expression involve recruitment of existing messenger RNAs to and away from polysomes.
Cancer Res. 66: 1052-61, 2006.
2)  Jamal M, Rath BH, Williams ES, Camphausen K, Tofilon PJ.
Microenvironmental regulation of glioblastoma radioresponse.
Clin. Cancer Res. 16: 6049-59, 2010.
3)  Hayman TJ, Williams ES, Jamal M, Shankavaram UT, Camphausen K, Tofilon PJ.
Translation Initiation Factor eIF4E Is a Target for Tumor Cell Radiosensitization.
Cancer Res. 72: 2362-72, 2012.
4)  Rath BH, Fair JM, Jamal M, Camphausen K, Tofilon PJ.
Astrocytes enhance the invasion potential of glioblastoma stem-like cells.
PLoS ONE. 8: e54752, 2013.
5)  Hayman TJ, Wahba A, Rath BH, Bae H, Kramp T, Shankavaram UT, Camphausen K, Tofilon PJ.
The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells.
Clin. Cancer Res. 20: 110-9, 2014.
6)  Kahn J, Hayman TJ, Jamal M, Rath BH, Kramp T, Camphausen K, Tofilon PJ.
The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells.
Neuro-oncology. 16: 29-37, 2014.
7)  Hayman TJ, Kramp T, Kahn J, Jamal M, Camphausen K, Tofilon PJ.
Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity.
Transl Oncol. 6: 355-62, 2013.
8)  Tandle AT, Kramp T, Kil WJ, Halthore A, Gehlhaus K, Shankavaram U, Tofilon PJ, Caplen NJ, Camphausen K.
Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation.
Eur. J. Cancer. 49: 3020-8, 2013.
9)  Arscott WT, Tandle AT, Zhao S, Shabason JE, Gordon IK, Schlaff CD, Zhang G, Tofilon PJ, Camphausen KA.
Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration.
Transl Oncol. 6: 638-48, 2013.
10)  Tandle AT, Shankavaram U, Brown MV, Ho J, Graves C, Lita E, Pfohl J, Mohney R, Tofilon PJ, Camphausen K.
Urinary metabolomic profiling of patients with glioblastoma multiforme.
J Proteomics Bioinform. February 26, 2013.
Full Text Article. [Journal]
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This page was last updated on 6/17/2014.