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Our Science – Brownell Website

Isaac Brownell, M.D., Ph.D.

Selected Publications

1)  Brownell I, Guevara E, Bai CB, Loomis CA, Joyner AL.
Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells.
Cell Stem Cell. 8: 552-65, 2011.
2)  Xiao Y, Woo W, Nagao K, Li W, Terunuma A, Mukouyama Y, Oro AE, Vogel JC, Brownell I.
Perivascular hair follicle stem cells associate with a venule annulus.
J. Invest. Dermatol. 133: 2324-31, 2013.
3)  Lok B, Khan S, Mutter R, Liu J, Fields R, Pulitzer M, Shi W, Zhang Z, Kraus D, Pfister D, Busam KJ, Brownell I, Lee N.
Selective radiotherapy for the treatment of head and neck Merkel cell carcinoma.
Cancer. 118: 3937-44, 2012.
4)  Xiao Y, Williams JS, Brownell I.
Merkel cells and touch domes: More than mechanosensory functions?.
Exp. Dermatol. [Epub ahead of print], 2014.
5)  Stamell EF, Wolchok JD, Gnjatic S, Lee NY, Brownell I.
The Abscopal Effect Associated With a Systemic Anti-melanoma Immune Response.
Int J Radiat Oncol Biol Phys. 85: 293-5, 2012.
6)  Williams JS, Xiao Y, Brownell I.
Low pH reprograms somatic murine cells into pluripotent stem cells: A novel technique with therapeutic implications.
Cancer Biol. Ther. 15, 2014.
7)  Salo-Mullen EE, Shia J, Brownell I, Allen P, Girotra M, Robson ME, Offit K, Guillem JG, Markowitz AJ, Stadler ZK.
Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome.
Fam. Cancer. [Epub ahead of print], 2014.
8)  Turegano MM, Lee CC, Malech HL, De Ravin SS, Cowen EW, Brownell I.
Recurrent erythematous plaques on sun-exposed sites in an African American boy with chronic granulomatous disease.
J. Am. Acad. Dermatol. 70: 576-80, 2014.
9)  Liu L, Kugler MC, Loomis CA, Samdani R, Zhao Z, Chen GJ, Brandt JP, Brownell I, Joyner AL, Rom WN, Munger JS.
Hedgehog Signaling in Neonatal and Adult Lung.
Am. J. Respir. Cell Mol. Biol. 48: 703-10, 2013.
10)  Strazzula L, Brown KK, Brieva JC, Camp BJ, Frankel HC, Kissin E, Mahlberg MJ, Mina MA, Pomeranz MK, Brownell I, Kroshinsky D.
Levamisole toxicity mimicking autoimmune disease.
J. Am. Acad. Dermatol. 69: 954-9, 2013.
11)  Geeraert P, Williams JS, Brownell I.
Targeting the hedgehog pathway to treat basal cell carcinoma.
J Drugs Dermatol. 12: 519-23, 2013.
12)  Firoz EF, Turnbull RK, Loomis CA, Brownell I.
Allergic Contact Dermatitis to Gamma-Irradiated WEBCOL Alcohol Prep Pads.
Pediatr Dermatol. 30: e281-2, 2012.
13)  Kovalyshyn I, Bijal AD, Lacouture ME, Brownell I.
Cyclophosphamide-associated acneiform drug eruption in a patient with multiple myeloma.
J. Am. Acad. Dermatol. 65: 657-9, 2011.
14)  Camp BJ, Busam KJ, Brownell I, Koehne G, Hedvat C, Pulitzer MP.
Donor-derived lymphomatoid papulosis in a stem-cell transplantation recipient.
J. Clin. Oncol. 29: e855-8, 2011.
15)  Brownell I, Rami­rez-Valle F, Sanchez M, Prystowsky S.
Evidence for Mycobacteria in Sarcoidosis.
Am J Respir Cell Mol Biol. 45: 899-905, 2011.
16)  Brooks C, Pulitzer MP, Brownell I.
Longitudinal lift biopsy technique with flat fixation for the diagnosis of mycosis fungoides.
Int. J. Dermatol. 50: 875-6, 2011.
17)  Rush Z, Fields RC, Lee N, Brownell I.
Radiation therapy in the management of Merkel cell carcinoma: current perspectives.
Expert Rev Dermatol. 6: 395-404, 2011.
18)  Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD.
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.
Development. 137: 3753-61, 2010.
19)  Tran TH, Jarrell A, Zentner GE, Welsh A, Brownell I, Scacheri PC, Atit R.
Role of canonical Wnt signaling/beta-catenin via Dermo1 in cranial dermal cell development.
Development. 137: 3973-84, 2010.
20)  Brownell I, Etzel CJ, Yang DJ, Taylor SH, Duvic M.
Increased malignancy risk in the cutaneous T-cell lymphoma patient population.
Clin Lymphoma Myeloma. 8: 100-5, 2008.
21)  Pielop JA, Brownell I, Duvic M.
Mycosis fungoides associated with malignant melanoma and dysplastic nevus syndrome.
Int. J. Dermatol. 42: 116-22, 2003.
Click Here to View Collapsed Bibliography.

This page was last updated on 6/16/2014.