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Our Science – Larson Website

Daniel R. Larson, Ph.D.

Selected Publications

1)  Larson DR, Fritzsch C, Sun L, Meng X, Lawrence DS, Singer RH.
Direct observation of frequency modulated transcription in single cells using light activation.
Elife. 2: e00750, 2013.
[Journal]
2)  Ferguson ML, Larson DR.
Measuring transcription dynamics in living cells using fluctuation analysis.
Methods Mol. Biol. 1042: 47-60, 2013.
[Journal]
3)  Trcek T, Larson DR, Moldón A, Query CC, Singer RH.
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast.
Cell. 147: 1484-97, 2011.
[Journal]
4)  Larson D, Zenklusen D, Wu B, Chao J, Singer R.
Real-time observation of transcription initiation and elongation on an endogenous yeast gene.
Science. 332: 475-8, 2011.
[Journal]
5)  Zenklusen D, Larson DR, Singer RH.
Single-RNA counting reveals alternative modes of gene expression in yeast.
Nat. Struct. Mol. Biol. 15: 1263-71, 2008.
[Journal]
6)  Larson DR, Zipfel WR, Williams RM, Clark SW, Bruchez MP, Wise FW, Webb WW.
Water-soluble quantum dots for multiphoton fluorescence imaging in vivo.
Science. 300: 1434-6, 2003.
[Journal]
7)  Coulon A, Chow CC, Singer RH, Larson DR.
Eukaryotic transcriptional dynamics: from single molecules to cell populations.
Nat. Rev. Genet. 14: 572-84, 2013.
[Journal]
8)  Palangat M, Larson DR.
Complexity of RNA polymerase II elongation dynamics.
Biochim Biophys Acta. 1819: 667-72, 2012.
[Journal]
9)  Trcek T, Chao JA, Larson DR, Park HY, Zenklusen D, Shenoy SM, Singer RH.
Single-mRNA counting using fluorescent in situ hybridization in budding yeast.
Nat Protoc. 7: 408-19, 2012.
[Journal]
10)  Larson DR.
What do expression dynamics tell us about the mechanism of transcription?.
Curr Opin Genet Dev. 5: 591-9, 2011.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 11/25/2013.