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Our Science – Bernal Website

Federico Bernal, Ph.D.

Selected Publications

1)  Yang Y, Schmitz R, Mitala JJ, Whiting A, Xiao W, Ceribelli M, Wright GW, Zhao H, Yang Y, Xu W, Rosenwald A, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Wiestner A, Kruhlak MJ, Iwai K, Bernal F, Staudt LM.
Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms.
Cancer Discov. 4: 480-93, 2014.
2)  de Lange J, Teunisse AF, Vries MV, Lodder K, Lam S, Luyten GP, Bernal F, Jager MJ, Jochemsen AG.
High levels of Hdmx promote cell growth in a subset of uveal melanomas.
Am J Cancer Res. 2: 492-507, 2012.
3)  Gembarska A, Luciani F, Fedele C, Russell EA, Dewaele M, Villar S, Zwolinska A, Haupt S, de Lange J, Yip D, Goydos J, Haigh JJ, Haupt Y, Larue L, Jochemsen A, Shi H, Moriceau G, Lo RS, Ghanem G, Shackleton M, Bernal F, Marine J.
MDM4 is a key therapeutic target in cutaneous melanoma.
Nat Med. 18: 1239-1247, 2012.
Full Text Article. [Journal]
4)  Bernal F, Wade M, Godes M, Davis TN, Whitehead DG, Kung AL, Wahl GM, Walensky LD.
A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53.
Cancer Cell. 18: 411-422, 2010.
Full Text Article. [Journal]
5)  Pitter K, Bernal F, Labelle J, Walensky LD.
Dissection of the BCL-2 family signaling network with stabilized alpha-helices of BCL-2 domains.
Meth. Enzymol. 446: 387-408, 2008.
6)  Bernal F, Raman JD.
Exploration of treatment options for the management of stage I testicular seminoma.
Expert Rev Anticancer Ther. 8: 1081-90, 2008.
7)  Bird GH, Bernal F, Pitter K, Walensky LD.
Synthesis and biophysical characterization of stabilized alpha-helices of BCL-2 domains.
Meth. Enzymol. 446: 369-86, 2008.
8)  Bernal F, Tyler AF, Korsmeyer SJ, Walensky LD, Verdine GL.
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.
J. Am. Chem. Soc. 129: 2456-7, 2007.
9)  Nicolaou KC, Pihko PM, Bernal F, Frederick MO, Qian W, Uesaka N, Diedrichs N, Hinrichs J, Koftis TV, Loizidou E, Petrovic G, Rodriquez M, Sarlah D, Zou N.
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.
J. Am. Chem. Soc. 128: 2244-57, 2006.
10)  Nicolaou KC, Chen DY, Li Y, Uesaka N, Petrovic G, Koftis TV, Bernal F, Frederick MO, Govindasamy M, Ling T, Pihko PM, Tang W, Vyskocil S.
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.
J. Am. Chem. Soc. 128: 2258-67, 2006.
Click Here to View Expanded Bibliography.

This page was last updated on 4/23/2014.