Our Science – Wang Website
Yisong Wang, Ph.D.
Selected Publications |
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| 1)
Voortman J, Harada T, Chang RP, Killian JK, Suuriniemi M, Smith WI, Meltzer PS, Lucchi M, Wang Y, Giaccone G. Detection and Therapeutic Implications of c-Met Mutations in Small Cell Lung Cancer and Neuroendocrine Tumors. Curr. Pharm. Des. 19: 833-40, 2013. [Journal] |
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| 2)
Petrini I, Meltzer PS, Zucali PA, Luo J, Lee C, Santoro A, Lee HS, Killian KJ, Wang Y, Tsokos M, Roncalli M, Steinberg SM, Wang Y, Giaccone G. Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors. Cell Death Dis. 3: e351, 2012. [Journal] |
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| 3)
Thomas A, Rajan A, Lopez-Chavez A, Wang Y, Giaccone G. From targets to targeted therapies and molecular profiling in non-small cell lung carcinoma. Ann. Oncol. 2012. [Journal] |
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| 4)
Lee JH, Giovannetti E, Hwang JH, Petrini I, Wang Q, Voortman J, Wang Y, Steinberg SM, Funel N, Meltzer PS, Wang Y, Giaccone G. Loss of 18q22.3 Involving the Carboxypeptidase of Glutamate-like Gene Is Associated with Poor Prognosis in Resected Pancreatic Cancer. Clin. Cancer Res. 18: 524-33, 2012. [Journal] |
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| 5)
Petrini P, French CA, Rajan A, Cameron MJ, Jaffe ES, Zucali PA, Xie J, Wang Y, Giaccone G. NUT rearrangement is uncommon in human thymic epithelial tumors. J Thorac Oncol. 7: 744-50, 2012. [Journal] |
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| 6)
Komiya T, Thomas A, Khozin S, Rajan A, Wang Y, Giaccone G. Response to Crizotinib inROS1-Rearranged Non-Small-Cell Lung Cancer. J. Clin. Oncol. 30: 3425-6, 2012. [Journal] |
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| 7)
Wang Y, Giaccone G. Challenges in cancer molecular targets and therapeutics. Front Oncol. 1: 4, 2011. [Journal] |
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| 8)
Lee JH, Voortman J, Dingemans AM, Voeller DM, Pham T, Wang Y, Giaccone G. MicroRNA expression and clinical outcome of small cell lung cancer. PLoS ONE. 6: e21300, 2011. [Journal] |
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| 9)
Harada T, Yatabe Y, Takeshita M, Koga T, Yano T, Wang Y, Giaccone G. Role and Relevance of TrkB Mutations and Expression in Non-Small Cell Lung Cancer. Clin. Cancer Res. 17: 2638-45, 2011. [Journal] |
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| 10)
Giaccone G, Wang Y. Strategies for overcoming resistance to EGFR family tyrosine kinase inhibitors. Cancer Treat. Rev. 37: 456-64, 2011. [Journal] |
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| 11)
Kelly RJ, Petrini I, Rajan A, Wang Y, Giaccone G. Thymic malignancies: from clinical management to targeted therapies. J. Clin. Oncol. 29: 4820-7, 2011. [Journal] |
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| 12)
Voortman J, Lee JH, Killian JK, Suuriniemi M, Wang Y, Lucchi M, Smith WI, Meltzer P, Wang Y, Giaccone G. Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors. Proc. Natl. Acad. Sci. U.S.A. 107: 13040-5, 2010. [Journal] |
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| 13)
Harada T, Lopez-Chavez A, Xi L, Raffeld M, Wang Y, Giaccone G. Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry. Oncogene. 2010. [Journal] |
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| 14)
Petrini I, Zucali PA, Lee HS, Pineda MA, Meltzer PS, Walter-Rodriguez B, Roncalli M, Santoro A, Wang Y, Giaccone G. Expression and mutational status of c-kit in thymic epithelial tumors. J Thorac Oncol. 5: 1447-53, 2010. [Journal] |
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| 15)
Rhee DB, Wang Y, Mizesko M, Zhou F, Haneline L, Liu Y. FANCC suppresses short telomere-initiated telomere sister chromatid exchange. Hum. Mol. Genet. 19: 879-87, 2010. [Journal] |
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| 16)
Wang Y, Trepel JB, Neckers LM, Giaccone G. STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer. Curr Opin Investig Drugs. 11: 1466-76, 2010. [Journal] |
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| 17)
Giannone RJ, McDonald HW, Hurst GB, Shen RF, Wang Y, Liu Y. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. PLoS ONE. 5: e12407, 2010. [Journal] |
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| 18)
Giannone RJ, Liu Y, Wang Y. The monitoring and affinity purification of proteins using dual tags with tetracysteine motifs. Methods Mol. Biol. 544: 421-38, 2009. [Journal] |
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| 19)
Pelletier DA, Hurst GB, Foote LJ, Lankford PK, McKeown CK, Lu TY, Schmoyer DD, Shah MB, Hervey WJ, McDonald WH, Hooker BS, Cannon WR, Daly DS, Gilmore JM, Wiley HS, Auberry DL, Wang Y, Larimer FW, Kennel SJ, Doktycz MJ, Morrell-Falvey JL, Owens ET, Buchanan MV. A general system for studying protein-protein interactions in Gram-negative bacteria. J. Proteome Res. 7: 3319-28, 2008. [Journal] |
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| 20)
Wu J, Cho HP, Rhee DB, Johnson DK, Dunlap J, Liu Y, Wang Y. Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication. J. Cell Biol. 181: 475-83, 2008. [Journal] |
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| 21)
Zou Y, Wu J, Giannone RJ, Boucher L, Du H, Huang Y, Johnson DK, Liu Y, Wang Y. Nucleophosmin/B23 negatively regulates GCN5-dependent histone acetylation and transactivation. J. Biol. Chem. 283: 5728-37, 2008. [Journal] |
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| 22)
Giannone RJ, McDonald WH, Hurst GB, Huang Y, Wu J, Liu Y, Wang Y. Dual-tagging system for the affinity purification of mammalian protein complexes. BioTechniques. 43: 296, 298, 300 passim, 2007. [Journal] |
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| 23)
Campbell MR, Wang Y, Andrew SE, Liu Y. Msh2 deficiency leads to chromosomal abnormalities, centrosome amplification, and telomere capping defect. Oncogene. 25: 2531-6, 2006. [Journal] |
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| 24)
Gomez M, Wu J, Schreiber V, Dunlap J, Dantzer F, Wang Y, Liu Y. PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres. Mol. Biol. Cell. 17: 1686-96, 2006. [Journal] |
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| 25)
Wang Y, Erdmann N, Giannone RJ, Wu J, Gomez M, Liu Y. An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres. Proc. Natl. Acad. Sci. U.S.A. 102: 10256-60, 2005. [Journal] |
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| 26)
Wang Y, Giannone RJ, Liu Y. Telomere sister chromatid exchange in telomerase deficient murine cells. Cell Cycle. 4: 1320-2, 2005. [Journal] |
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| 27)
Cho HP, Liu Y, Gomez M, Dunlap J, Tyers M, Wang Y. The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules. Mol. Cell. Biol. 25: 4541-51, 2005. [Journal] |
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| 28)
Thyrell L, Sangfelt O, Zhivotovsky B, Pokrovskaja K, Wang Y, Einhorn S, Grandér D. The HPV-16 E7 oncogene sensitizes malignant cells to IFN-alpha-induced apoptosis. J. Interferon Cytokine Res. 25: 63-72, 2005. [Journal] |
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| 29)
Wang Y, Penfold S, Tang X, Hattori N, Riley P, Harper JW, Cross JC, Tyers M. Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Curr. Biol. 9: 1191-4, 1999. [Journal] |
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| 30)
Shick L, Carman JH, Choi JK, Somasundaram K, Burrell M, Hill DE, Zeng YX, Wang Y, Wiman KG, Salhany K, Kadesch TR, Monroe JG, Donehower LA, el-Deiry WS. Decreased immunoglobulin deposition in tumors and increased immature B cells in p53-null mice. Cell Growth Differ. 8: 121-31, 1997. [Journal] |
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| 31)
Silva S, Wang Y, Babonits M, Imreh S, Wiener F, Klein G. Spontaneous development of plasmacytomas in a selected subline of BALB/cJ mice. Eur. J. Cancer. 33: 479-85, 1997. [Journal] |
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| 32)
Varmeh-Ziaie S, Okan I, Wang Y, Magnusson KP, Warthoe P, Strauss M, Wiman KG. Wig-1, a new p53-induced gene encoding a zinc finger protein. Oncogene. 15: 2699-704, 1997. [Journal] |
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| 33)
Wang Y, Okan I, Pokrovskaja K, Wiman KG. Abrogation of p53-induced G1 arrest by the HPV 16 E7 protein does not inhibit p53-induced apoptosis. Oncogene. 12: 2731-5, 1996. [Journal] |
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| 34)
Wang Y, Okan I, Szekely L, Klein G, Wiman KG. bcl-2 inhibits wild-type p53-triggered apoptosis but not G1 cell cycle arrest and transactivation of WAF1 and bax. Cell Growth Differ. 6: 1071-5, 1995. [Journal] |
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| 35)
Qian W, Hu LF, Chen F, Wang Y, Magnusson KP, Kashuba E, Klein G, Wiman KG. Infrequent MDM2 gene amplification and absence of gross WAF1 gene alterations in nasopharyngeal carcinoma. Eur. J. Cancer, B, Oral Oncol. 31B: 328-32, 1995. [Journal] |
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| 36)
Szekely L, Wang Y, Klein G, Wiman KG. RB-reconstituted human retinoblastoma cells form RB-positive intraocular and intracerebral but not subcutaneous tumors in SCID mice. Int. J. Cancer. 61: 683-91, 1995. [Journal] |
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| 37)
Sugiyama H, Silva S, Wang Y, Klein G. Strain-related cellular mechanisms as a determinant for susceptibility and resistance to PC induction. Curr. Top. Microbiol. Immunol. 194: 93-7, 1995. [Journal] |
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| 38)
Axelson H, Henriksson M, Wang Y, Magnusson KP, Klein G. The amino-terminal phosphorylation sites of C-MYC are frequently mutated in Burkitt's lymphoma lines but not in mouse plasmacytomas and rat immunocytomas. Eur. J. Cancer. 31A: 2099-104, 1995. [Journal] |
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| 39)
Okan I, Wang Y, Chen F, Hu LF, Imreh S, Klein G, Wiman KG. The EBV-encoded LMP1 protein inhibits p53-triggered apoptosis but not growth arrest. Oncogene. 11: 1027-31, 1995. [Journal] |
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| 40)
Imreh S, Wang Y, Panda CK, Babonits M, Axelson H, Silva S, Szeles A, Wiener F, Klein G. Hypersomy of chromosome 15 with retrovirally rearranged c-myc, loss of germline c-myc and IgK/c-myc juxtaposition in a macrophage-monocytic tumour line. Eur. J. Cancer. 30A: 994-1002, 1994. [Journal] |
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| 41)
Axelson H, Wang Y, Silva S, Mattei MG, Klein G. Juxtaposition of N-myc and Ig kappa through a reciprocal t(6;12) translocation in a mouse plasmacytoma. Genes Chromosomes Cancer. 11: 85-90, 1994. [Journal] |
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| 42)
Liu Y, Heyman M, Wang Y, Falkmer U, Hising C, Székely L, Einhorn S. Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells. Int. J. Cancer. 58: 663-7, 1994. [Journal] |
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| 43)
Sugiyama H, Wang Y, Jackson P, Sawyers CL, Klein G. Molecular requirements for rapid plasmacytoma and pre-B lymphoma induction by Abelson murine leukemia virus in myc-transgenic mice. Int. J. Cancer. 58: 135-41, 1994. [Journal] |
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| 44)
el-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Burrell M, Hill DE, Wang Y. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54: 1169-74, 1994. [Journal] |
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| 45)
Wang Y, Ramqvist T, Szekely L, Axelson H, Klein G, Wiman KG. Reconstitution of wild-type p53 expression triggers apoptosis in a p53-negative v-myc retrovirus-induced T-cell lymphoma line. Cell Growth Differ. 4: 467-73, 1993. [Journal] |
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| 46)
Ramqvist T, Magnusson KP, Wang Y, Szekely L, Klein G, Wiman KG. Wild-type p53 induces apoptosis in a Burkitt lymphoma (BL) line that carries mutant p53. Oncogene. 8: 1495-500, 1993. [Journal] |
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| 47)
Wang Y, Szekely L, Okan I, Klein G, Wiman KG. Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line. Oncogene. 8: 3427-31, 1993. [Journal] |
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| 48)
Silva S, Wang Y, Babonits M, Axelson H, Wiener F, Klein G. An exceptional mouse plasmacytoma with a new kappa/N-myc [T(6; 12) (C1; B)] translocation expresses N-myc but not c-myc. Curr. Top. Microbiol. Immunol. 182: 251-9, 1992. [Journal] |
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| 49)
Wang Y, Sugiyama H, Axelson H, Panda CK, Babonits M, Ma A, Steinberg JM, Alt FW, Klein G, Wiener F. Functional homology between N-myc and c-myc in murine plasmacytomagenesis: plasmacytoma development in N-myc transgenic mice. Oncogene. 7: 1241-7, 1992. [Journal] |
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This page was last updated on 2/12/2013.
