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Ji Luo, Ph.D.

Selected Publications

1)  Weng MT, Lee JH, Wei SC, Li Q, Shahamatdar S, Hsu D, Schetter AJ, Swatkoski S, Mannan P, Garfield S, Gucek M, Kim MK, Annunziata CM, Creighton CJ, Emanuele MJ, Harris CC, Sheu JC, Giaccone G, Luo J.
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 109: E3659-67, 2012.
2)  Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ.
Recurrent hemizygous deletions in cancers may optimize proliferative potential.
Science. 337: 104-9, 2012.
3)  Petrini I, Meltzer PS, Zucali PA, Luo J, Lee C, Santoro A, Lee HS, Killian KJ, Wang Y, Tsokos M, Roncalli M, Steinberg SM, Wang Y, Giaccone G.
Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors.
Cell Death Dis. 3: e351, 2012.
4)  Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, Shaw CA, Elledge SJ, Westbrook TF.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Science. 335: 348-53, 2012.
5)  Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG.
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.
Proc. Natl. Acad. Sci. U.S.A. 109: 5322-7, 2012.
6)  Hu G, Luo J.
A primer on using pooled shRNA libraries for functional genomic screens.
Acta Biochim. Biophys. Sin. (Shanghai). 44: 103-12, 2012.
7)  Luo J.
Cancer's sweet tooth for serine.
Breast Cancer Res. 13: 317, 2011.
8)  Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T.
Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.
Cell Metab. 12: 619-32, 2010.
9)  Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR.
The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Cancer Res. 70: 5305-15, 2010.
10)  Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.
Cell. 137: 835-48, 2009.
Click Here to View Expanded Bibliography.

This page was last updated on 5/8/2013.