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Our Science – Tropea Website

Joseph E. Tropea, Ph.D.

Selected Publications

1)  Hogan M, Bahta M, Cherry S, Lountos GT, Tropea JE, Zhao BM, Burke TR, Waugh DS, Ulrich RG.
Biomolecular Interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase.
Chem Biol Drug Des. 81: 323-33, 2013.
[Journal]
2)  Raran-Kurussi S, Tözsér J, Cherry S, Tropea JE, Waugh DS.
Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases.
Anal. Biochem. 436: 142-4, 2013.
[Journal]
3)  Lountos GT, Tropea JE, Waugh DS.
Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas" disease.
Mol. Biochem. Parasitol. 187: 1-8, 2013.
[Journal]
4)  Lountos GT, Tropea JE, Waugh DS.
Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system.
Acta Crystallogr. D Biol. Crystallogr. 68: 201-9, 2012.
[Journal]
5)  Sun P, Tropea JE, Waugh DS.
Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner.
Methods Mol. Biol. 705: 259-74, 2011.
[Journal]
6)  Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS.
Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy.
J. Struct. Biol. 176: 292-301, 2011.
[Journal]
7)  Lountos GT, Tropea JE, Waugh DS.
Structure of human dual-specificity phosphatase 27 at 2.38 angstrom resolution.
Acta Crystallogr. D Biol. Crystallogr. 67: 471-9, 2011.
[Journal]
8)  Tu C, Zhou X, Tarasov SG, Tropea JE, Austin BP, Waugh DS, Court DL, Ji X.
The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc. Natl. Acad. Sci. U.S.A. 108: 10156-61, 2011.
[Journal]
9)  Austin BP, Tözsér J, Bagossi P, Tropea JE, Waugh DS.
The substrate specificity of Metarhizium anisopliae and Bos taurus carboxypeptidases A: insights into their use as tools for the removal of affinity tags.
Protein Expr. Purif. 77: 53-61, 2011.
[Journal]
10)  Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS.
X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket.
FEBS Lett. 585: 3245-9, 2011.
[Journal]
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This page was last updated on 5/9/2013.