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Our Science – Yang Website

Li Yang, Ph.D.

Selected Publications

1)  Pang Y, Gara SK, Achyut BR, Li Z, Yan HH, Day CP, Weiss JM, Trinchieri G, Morris JC, Yang L.
TGF-ß Signaling in Myeloid Cells Is Required for Tumor Metastasis.
Cancer Discov. 3: 936-51, 2013.
2)  Achyut BR, Bader DA, Robles AI, Wangsa D, Harris CC, Ried T, Yang L.
Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-beta signaling.
PLoS Genet. 9: e1003251, 2013.
3)  Yan HH, Pickup M, Pang Y, Gorska AE, Li Z, Chytil A, Geng Y, Gray JW, Moses HL, Yang L.
Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung.
Cancer Res. 70: 6139, 2010.
4)  Li Z, Pang Y, Gara SK, Achyut BR, Heger C, Goldsmith PK, Lonning S, Yang L.
Gr-1+CD11b+ cells are responsible for tumor promoting effect of TGF-beta in breast cancer progression.
Int. J. Cancer. 131: 2584-95, 2012.
5)  Yang L, Pang Y, Moses HL.
TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression.
Trends Immunol. 31: 220-7, 2010.
6)  Luger D, Yang YA, Raviv A, Weinberg D, Banerjee S, Lee MJ, Trepel J, Yang L, Wakefield LM.
Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects.
PLoS ONE. 8: e76115, 2013.
7)  Seton-Rogers S.
Microenvironment: Making connections.
Nat. Rev. Cancer. 13: 222-3, 2013.
8)  Faraji F, Pang Y, Walker RC, Nieves Borges R, Yang L, Hunter KW.
Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity.
PLoS Genet. 8: e1002926, 2012.
9)  Min Y, Ghose S, Boelte K, Li J, Yang L, Lin PC.
C/EBP-delta regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1alpha.
Oncogene. 30: 4901-9, 2011.
10)  Huang Y, Lin L, Shanker A, Malhotra A, Yang L, Dikov MM, Carbone DP.
Resuscitating cancer immunosurveillance: selective stimulation of DLL1-Notch signaling in T cells rescues T-cell function and inhibits tumor growth.
Cancer Res. 71: 6122-31, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 6/17/2014.