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Our Science – Kalab Website

Petr Kalab, Ph.D.

Selected Publications

1)  Kalab P, Pu RT, Dasso M.
The Ran GTPase regulates mitotic spindle assembly.
Curr. Biol. 9: 481-4, 1999.
2)  Kalab P, Weis K, Heald R.
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts.
Science. 295: 2452-6, 2002.
3)  Kalab P, Pralle A, Isacoff EY, Heald R, Weis K.
Analysis of a RanGTP-regulated gradient in mitotic somatic cells.
Nature. 440: 697-701, 2006.
4)  Kalab P, Heald R.
The RanGTP gradient - a GPS for the mitotic spindle.
J. Cell. Sci. 121: 1577-86, 2008.
5)  Hasegawa K, Ryu SJ, Kaláb P.
Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.
J. Cell Biol. 200: 151-61, 2013.
6)  Soderholm JF, Bird SL, Kalab P, Sampathkumar Y, Hasegawa K, Uehara-Bingen M, Weis K, Heald R.
Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-beta.
ACS Chem. Biol. 6: 700-8, 2011.
7)  Halpin D, Kalab P, Wang J, Weis K, Heald R.
Mitotic Spindle Assembly around RCC1-Coated Beads in Xenopus Egg Extracts.
PLoS Biol. 9: e1001225, 2011.
8)  Kaláb P, Solc P, Motlík J.
The role of RanGTP gradient in vertebrate oocyte maturation.
Results Probl Cell Differ. 53: 235-67, 2011.
9)  Lowe AR, Siegel JJ, Kalab P, Siu M, Weis K, Liphardt JT.
Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking.
Nature. 467: 600-3, 2010.
10)  Kalab P, Soderholm J.
The design of Foerster (fluorescence) resonance energy transfer (FRET)-based molecular sensors for Ran GTPase.
Methods. 51: 220-32, 2010.
Click Here to View Expanded Bibliography.

This page was last updated on 6/19/2014.